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fungals c.5-1
| Question | Answer |
|---|---|
| what is a fungus | a single cell organism similar to a human cell. |
| how is fungus cell similar to a human cell | fungal cell wall contains ergosterol, similar to cholestrol. which is the basis for antifungal drugs which prohibit its synthesis.fungus can't produce ergosterol, cell wall falls apart |
| what is onychomycosis | nail fungus |
| what does mycosis mean | fungus |
| name fungal infection 1of5 | Aspergillosis - skin, lungs, bones |
| name fungual infection 2of5 | Candidiasis - usually superficial, vaginal yeast infection, thrush, diaper rash |
| name fungal infection 3of5 | Tinea - jock itch, ringworm, athlete's foot note- tinia pedis is foot---tinia cap - head |
| name fungal infection 4of5 | Cryptococcus - CNS INFECTION(brain) usually aids patients |
| name fungal infection 5of5 | Histoplasmosis - pneumonia |
| antifungals brand/generic and use | FUNGIZONE (amphotericin B) for blood-borne life threating infections |
| how should amphotericin B be administered to patient | infuse slowly. do not mix with normal saline/mix with D5W. check vital signs during infusion. prophylaxis with benadryl or acetaminophen may be necessry to prevent infusion related side effects |
| amphotericin B side effect | phlebitis is common and may cause nephrotoxicity |
| antifungal brand/generic & use | ANCOBON (flucytosine) given synergistically with amphotericin B to treat systemic candida and cryptococcus infections |
| ANCOBON (flucytosine) side effects | rash gi upset |
| antifungal(triazoles)---name drug-used for | VFEND (voriconazole) is an alternative to amphotericin B for life threating infections |
| VFEND (voriconazole) also know as conazole side effect | liver toxicity or blurred vision |
| VFEND (voriconazole) warnings | DO NOT DRIVE AT NIGHT |
| VFEND(voriconazole) if you are taking phenytoin what could happen | cause need for increased dose(excreates to guickly) |
| antifungal (triazoles)---name drug-used for | DIFLUCAN(FLUCONAZOLE) one day does for yeast infection |
| DIFLUCAN(FLUCONAZOLE) side effect | hepatotoxicity (most antifungla cause liver damage) |
| antifungals(triazoles)---name drug-used for | SPORANOX(itraconazole) Most common for nail infections |
| SPORANOX (itraconazole) warnings | take with fatty meal, no antacids or h2 blockers.--CONTRAINDICATED CHF (congestive heart failure) |
| antifungal (triazole)---name drug--used for | NOXAFIL(posaconazole) Prophylaxis for immunocompromised patients (prevents fungal infection in hiv patient) |
| NOXAFIL (POSACONAZOLE) warning | TAKE WITH FOOD |
| antifungal OTC--name and use | LAMISIL (terbinafine) orally for nail infection. |
| LAMISIL (TERBINAFINE) DOSAGE FORM | orally -nail infection, topically - athlete's foot, jock itch and ringworm |
| LAMISIL (terbinafine) side effects | CYP 450 INHIBITOR- MAY CAUSE LIVER AND KIDNEY DAMAGE, STEVENS-JOHNSON syndrome |
| ANTIFUNGAL OTC--NAME AND USE | LOTRIMIN ULTRA (butenafine) jock itch, athlete's foot and ringworm (better) TOPICAL |
Created by:
jddmmin7
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