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Pharm: Kee45: Def
Pharm: Kee Ch45: Anticoagulants, Antiplatelets, & Thrombolytics: Definitios
| Question | Answer |
|---|---|
| Aggregation | Clumping together of platelets to form a clot |
| Thrombosis | Formation of a clot in an arterial or venous vessel |
| Anticoagulants | Inhibit clot formation |
| Myocardial infaction/ Acute MI | Heart attack |
| Partial thromboplasin time (PTT) & Activated partial thromboplastin time (aPTT) | Lab tests: detect deficiencies of certain clotting factors; used to monitor heparin therapy |
| Prothrombin time (PT) | Lab test that measures time it takes blood to clot in presence of certain clotting factors |
| International normalized ratio | Lab test most frequently used to report PT results |
| Antiplatelets | Prevent thrombosis in arteries by suppressing platelet aggregation |
| Thromboembolism | Occlusion of an artery or vein caused by thrombus or embolus |
| Ischemia | Deficient blood flow |
| Necrosis | Death |
| Thrombolytics | Promote fibrinolytic mechanism; convert plasminogen to plasmin, destroys fibrin in blood clot |
| Fibrinolysis | Fibrin breakdown |