Busy. Please wait.

show password
Forgot Password?

Don't have an account?  Sign up 

Username is available taken
show password


Make sure to remember your password. If you forget it there is no way for StudyStack to send you a reset link. You would need to create a new account.
We do not share your email address with others. It is only used to allow you to reset your password. For details read our Privacy Policy and Terms of Service.

Already a StudyStack user? Log In

Reset Password
Enter the associated with your account, and we'll email you a link to reset your password.

Remove Ads
Don't know
remaining cards
To flip the current card, click it or press the Spacebar key.  To move the current card to one of the three colored boxes, click on the box.  You may also press the UP ARROW key to move the card to the "Know" box, the DOWN ARROW key to move the card to the "Don't know" box, or the RIGHT ARROW key to move the card to the Remaining box.  You may also click on the card displayed in any of the three boxes to bring that card back to the center.

Pass complete!

"Know" box contains:
Time elapsed:
restart all cards

Embed Code - If you would like this activity on your web page, copy the script below and paste it into your web page.

  Normal Size     Small Size show me how


pharmacology notes

Agonist Brings about effect after binding to a receptor. low affinity. high efficacy
Types of agonist -Partial agonist -Inverse agonist
Acetylcholin agonist -Neostigmine -Physostigmine
Acetylcholin antagonist -Curare -Atropine
Types of cholin transporters -High affinity -Low affinity
High affinity cholin transporter Dependent on ATP
Low affinity cholin transporter Dependent on extra-cellular cholin concentrations
Break down of Acetylcholin Acetylcholinesterases [ACHE]
Synthesis of Acetylcholin Cholin acetyltransferases [CHAT]
Precursor of Acetylcholin -Cholin -Acetyl CoA
Inactivation of cholin transporters Hemicholinium
SNARE proteins Enable and facilitate the release of the ACH from the vesicles,by enabling the vesicle to bind to the membrane
Botulinum toxin [botox] breaks down SNARE proteins
Inhibit the release of ACH from the vesicles Botulinum toxin
COX [cyclo oxyginase] enzyme inhibitor NSAIDS
COX 1 -Homeostasis -protective mucus for lining the stomch
COX 2 -Involved in inflammation
NSAIDs -Anti inflammation -Antipyretic -Analgesic
LOX enzyme [lysyl oxidase] product leukotrienes
Leukotrienes Potent broncho constrictors
LOX antagonists -Montelukast -Enfirlukast
types of NSAIDs and their examples -Salicylic acid:acetyl salicylic acid [aspirin] -P amino phenol:[paracetamol] -Indol -Cnolics:[Oxicams]
Types of Cytokines -Interleukines -Interferons -Tissue necrotic factor
Interleukines Synthesised by T-lymphocytes and helper CD4
Interferons Released by cells which have been invaded by a bacteria. -have febril symptoms
Cytokines funtion Intracellular communication
Inflammation mediators -Breadykinin -Histamine -Prostaglandins -leukotrienes -cytokines -platelet activating factor
Platelet Activating Factor involved in inflammation
Vaso dilation causes! -decrease in blood pressure
Contraction of smooth muscles can lead to - Broncho constriction
Prostaglandin analogues Prostanoids
Prostanoids used in Termination Of Pregnancy[TOP] -Gemeprost -Misoprost
Types of Prostaglandins -PgH2 -PgI2 -Thromboxane A2 and B2 -PgE -PgF2 alpha
PgI2 -Inhibits platelet aggregation -Dilator
PgF2 alpha -Powerful uterine contractions -Potent broncho constrictor
Thromboxane A2 -Vaso constictor
PgG2 -Vaso dilator -GIT relaxation -ionotropic
Ionotropic affects the force of muscular contraction
PgEp1 -Broncho constrictor -Vaso constritor
PgEp2 -Broncho dilator -caso dilator
Lipid derieved mediators -Prostaglandins -Leukotrienes
Substrate for LOX and COX Arachidonic acid
Lipokotien Inhibits Phospho lipase A -stimulated by glucocortecoids
Types of Histamine receptors -H1 -H2 -H3
H1 antagonist -Promethazine -Cyclizine
Motion sickness drugs -Promethazine -Cyclizine
Cimetidine side effects -Inhibits liver enzyme Cytochrome P450
H2 antagonist -Cimetidine -Ranitidine
Antihistamines have similar effects as- Atropin
Atropin Anti-cholinergic -Competitive antagonist
Angiotensin Converting Enzyme [ACE] Breaks down breadykinin
ACE inhibitors -Enalapril -Captopril
Histamine synthesized from L-histadine
ACE inhibitors pharmacological effect Decrease blood pressure,since breadykinins are vaso-dilators
Characteristics of inflammation -swelling -pain -heat -redness -loss of function
Types of paralyzing agents Non depolarizing agents Depolarizing agents
Non-depolarizing blockers curariform agents
Curariform agents D tubocurarine,Dimethyl tubocurarine
Non depolarizing agents Do not cause any effect before paralysis
D tubocurarine analogus Alcuronium,Puncuronium,Gallamine, Atracurium
Created by: 100000821506952