Save
Busy. Please wait.
or

show password
Forgot Password?

Don't have an account?  Sign up 
or

Username is available taken
show password

why


Make sure to remember your password. If you forget it there is no way for StudyStack to send you a reset link. You would need to create a new account.
We do not share your email address with others. It is only used to allow you to reset your password. For details read our Privacy Policy and Terms of Service.


Already a StudyStack user? Log In

Reset Password
Enter the associated with your account, and we'll email you a link to reset your password.
focusNode
Didn't know it?
click below
 
Knew it?
click below
Don't know
Remaining cards (0)
Know
0:00
share
Embed Code - If you would like this activity on your web page, copy the script below and paste it into your web page.

  Normal Size     Small Size show me how

Pharm Ch18

Cardiac Rhythym

QuestionAnswer
MOA of Quinidine, Procainamide, Disopyramide Class IA Antiarrhythmic Agents (Na+ & K+channel blockers)
MOA of Lidocaine, Mexiletine, Phenytoin Class IB: bind to both open & inactivated Na+ channels, use-dependent block
MOA of Flecainide, Encainide, Moricizine, Propafenone Class IC: the most potent Na+ channel blockers (long half-life, but can also cause arrhythmia-CI w/ history of MI)
Class IA antiarrhythmic that is vagolytic and increases levels of digoxin Quinidine
Class IA antiarrhythmic that can cause lupus-like syndrome Procainamide
Class IA antiarrhythmic that is CI in obstructive uropathy, glaucoma, AV block, sinus node dys, uncomp HF Disopyramide
Class IB antiarrhythmic that has short half-life & does not prolong QT Lidocaine
Class IB antiarrhythmic that does not prolong QT, is used in combo w/ amiodarone for ICD, VT, also combo w/ quinidine or sotalol ADR: nausea, tremor (less if taken w/ food) Mexiletine
Class IB antiarrhythmic that is also an antiepileptic; used to treat VT in young children & congenital prolong QT; also inducer of P450 Phenytoin
MOA of "-olol", "-ilol" and "-alol" Class II Antiarrhythmic Agents (B-adrenergic Antagonists)
nonselective, does not prolong QT, first-gen, Tx: VT, ADR: bronchospasm, cold extremities, impotence Propranolol
selective B1, second gen; ADR: excessive negative inotrope, heart block, bradycardia Atenolol Metoprolol Acebutolol Bisoprolol
selective B1, third-gen, cause vasodilation by blocking a-adrenergic-R vasoconstriction Labetalol Carvedilol
selective B1, third-gen, cause vasodilation by being partial agonist at B2-adrenergic-R Pindolol
MOA of Ibutilide, Dofetilide, Sotalol, Bretylium, Amiodarone Class III Antiarrhythmic Agents (Inhibitors of Repolarization by blocking K+ channel)
Class III antiarrhythmics that can cause torsades de pointes Ibutilide Dofetilide Sotalol Bretylium
Class III antiarrhythmic that is mixed class II/III Sotalol
Class III antiarrhythmic that is used for anti-HTN and is antiarrhythmic at Purkinje fibers (no effect on atria) Bretylium
Class III antiarrhythmic that can also act as class I, II & IV by altering lipid membrane where ion channels & receptors are located, and resembles thyroxine (must monitor lung, thyroid, LFTs!) Amiodarone
Class III antiarrhythmic that can cause hypotension, pneumonitis & pulmonary fibrosis Amiodarone
MOA of Nifedipine, Verapamil, Diltiazem Class IV Antiarrhythmic Agents (Ca2+ channel blockers at SA/AV node)
Class IV antiarrhythmic that treats Prinzmetal angina Verapamil
Class IV antiarrhythmics that increase digoxin levels and affects cardiac tissue Verapamil Diltiazem
Inhibits Ca2+ channel at AV node, short half-life, used to treat narrow-complex PSVT, ADRs: HA, flushing, chest pain, bronchoconstriction, transient new arrhythmia Adenosine
Correction of what ion imbalance can terminate some arrhythmias? Potassium (hypo or hyperkalemia)
Improves exercise capacity, Tx: chronic stable angina, ADRs: Nausea, constipation, dizziness, prolongs QT Ranolazine
Created by: fmuralid
 

 



Voices

Use these flashcards to help memorize information. Look at the large card and try to recall what is on the other side. Then click the card to flip it. If you knew the answer, click the green Know box. Otherwise, click the red Don't know box.

When you've placed seven or more cards in the Don't know box, click "retry" to try those cards again.

If you've accidentally put the card in the wrong box, just click on the card to take it out of the box.

You can also use your keyboard to move the cards as follows:

If you are logged in to your account, this website will remember which cards you know and don't know so that they are in the same box the next time you log in.

When you need a break, try one of the other activities listed below the flashcards like Matching, Snowman, or Hungry Bug. Although it may feel like you're playing a game, your brain is still making more connections with the information to help you out.

To see how well you know the information, try the Quiz or Test activity.

Pass complete!

"Know" box contains:
Time elapsed:
Retries:
restart all cards