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c10-14 terms pt 2

pht 101

QuestionAnswer
beta blocker a Class II antiarrhythmic drug that competitively blocks response to beta stimulation, which results in decreases in heart rate, myocardial contractility, blood pressure, and myocardial oxygen demand; used to treat arrhythmias, MIs, and angina
blood pressure (BP) the product of cardiac output (CO) and total peripheral resistance (TPR)
bowel evacuant an agent that stimulates bowel content removal by increasing osmolarity of bowel fluids
bursitis inflammation of a bursa
calcium channel blocker a Class IV antiarrhythmic drug that prevents the movement of calcium ions through slow channels; used for most supraventricular tachyarrhythmias and in angina
carbonic anhydrase inhibitors diuretics that act in the proximal tubule to increase urine volume and change the pH to alkaline
circadian rhythm regular recurrence in cycles of twenty-four hours
climacteric the syndrome of endocrine, somatic, and psychic changes occurring at the end of the reproductive period in females
clotting cascade a series of events that initiate blood clotting, or coagulation
contractility the cardiac muscle's capacity for becoming shorter in response to a stimulus; along with preload and afterload, determines cardiac output
Crohn's disease an inflammatory bowel disease affecting the entire GI tract from mouth to anus
Cushing's disease a disease caused by overproduction of steroids or by excessive administration of corticosteroids over an extended period
cyclooxygenase-1 (COX-1) an enzyme that is present in most body tissues and produces protective prostaglandins to regulate physiological processes such as GI mucosal integrity
cyclooxygenase-2 (COX-2) an enzyme that is present in the synovial fluid of arthritis patients and is associated with the pain and inflammation of arthritis
diastolic blood pressure the blood pressure measurement that measures the pressure during the dilation of the heart
disease-modifying antirheumatic drugs (DMARDs) agents that can potentially modify the progression of rheumatoid arthritis
diuretic a substance that rids the body of excess fluid and electrolytes by increasing the urine output
diverticular disease an outpocketing from the colon wall that becomes inflamed
duodenal ulcer a peptic lesion situated in the duodenum
dyspareunia painful intercourse
estrogens hormones that stimulate the growth of reproductive tissue in females
fiber the undigested residue of fruits, vegetables, and other foods of plant origin that remains after digestion by the human GI enzymes; characterized by fermentability and may be either water soluble or insoluble
fibrinolytics a class of agents that dissolve clots
filtration the removal of substances from the blood as part of the formation of urine by the renal tubules
gastric ulcer a local excavation in the gastric mucosa
gastritis irritation and superficial erosion of the stomach lining
gastroesophageal reflux disease (GERD) a GI disease characterized by radiating burning or pain in the chest and an acid taste, caused by backflow of acidic stomach contents across an incompetent lower esophageal sphincter; also referred to as heartburn
gestational diabetes diabetes that occurs during pregnancy when insufficient insulin is produced
glucocorticoid corticosteroid involved in metabolism and immune system regulation
gluconeogenesis the process of forming new glucose, in which protein and fatty acids are converted into immediate energy sources
gouty arthritis a disease resulting from the improper excretion of uric acid; also called gout
Helicobacter pylori (H. pylori) a bacterium that contributes to the development of many gastric ulcers
hematocrit the proportion of red blood cells to the total volume of blood
hemorrhoids engorgements of the vascular cushions situated within the sphincter muscles; result from pressure exerted on anal veins while straining to pass a stool
high-density lipoproteins (HDLs) lipoproteins containing 5% triglyceride, 25% cholesterol, and 50% protein; "good cholesterol"
hirsutism abnormal hairiness, especially in women
histamine2 (H2) receptor antagonists agents that block acid and pepsin secretion in response to histamine, gastrin, foods, distention, caffeine, or cholinergic stimulation; used to treat GERD and H. pylori
hypercholesterolemia excessive cholesterol in the blood
hyperlipidemia elevation of the levels of one or more of the lipoproteins in the blood
hypertension elevated blood pressure, where systolic blood pressure is greater than 140 mm Hg and diastolic pressure is greater than 90 mm Hg
hypoglycemia blood glucose less than 70 mg/dL
hypogonadism a deficiency of hormone production and secretion
hypothyroidism a deficiency of thyroid activity that results in a decreased metabolic rate, tiredness, and lethargy in adults and causes cretinism in children
impotence failure of the male to initiate or to maintain an erection until ejaculation
International Normalized Ratio (INR) a method of standardizing the prothrombin time (PT) by comparing it to a standard index
irritable bowel syndrome (IBS) a functional disorder in which the lower GI tract does not have appropriate tone or spasticity to regulate bowel activity
lipoproteins spherical particles containing a core of triglycerides and cholesterol, in varying proportions, surrounded by a surface coat of phospholipids so that they can remain in solution
loop diuretics diuretics that inhibit reabsorption of sodium and chloride in the loop of Henle, thereby causing increased urinary output
low-density lipoproteins (LDLs) lipoproteins containing 6% triglycerides and 65% cholesterol; "bad cholesterol"
malabsorption syndrome impaired intestinal absorption of nutrients
mineralocorticoid corticosteroid involved in electrolyte and water balance
nephrons glomerulotubular units that are the working units of the kidney
nonnarcotic analgesics drugs used for pain, inflammation, and fever that are not controlled substances
nonsteroidal anti-inflammatory drugs (NSAIDs) anti-inflammatory, analgesic, and antipyretic drugs that are not scheduled; used to treat arthritis and for other indications such as pain and inflammation
oral contraceptives (OCs) hormonal compounds taken orally to prevent the occurrence of pregnancy
osmotic diuretic a diuretic that increases the osmotic pressure of glomerular filtrate, thereby inhibiting tubular reabsorption of water and electrolytes and increasing urinary output
osmotic laxatives stool softeners that draw water into the colon and thereby stimulate evacuation
osteoarthritis a degenerative joint disease resulting in loss of cartilage, elasticity, and thickness
partial thromboplastin time (PTT) a test that measures the function of the intrinsic and common pathways; affected by heparin
peptic ulcer an ulcer formed at any part of the GI tract exposed to acid and the enzyme pepsin
potassium-sparing diuretics diuretics that result in an exchange of the sodium excreted in urine for the potassium returned to the blood
preload the mechanical state of the heart at the end of diastole; along with afterload and contractility, determines cardiac output
progestins pure, synthetic hormones that emulate the effects of progesterone, which prepares the uterus for the reception and development of the fertilized ovum`
prothrombin time (PT) a test that assesses the function of the extrinsic pathways of the coagulation system; affected by warfarin
pulmonary embolism (PE) sudden blocking of the pulmonary artery by a blood clot
reabsorption the process by which substances are pulled back into the blood after waste products have been removed during the formation of urine
reflux backflow; specifically in GERD, the backflow of acidic stomach contents across an incompetent lower esophageal sphincter
reticulocytes immature red blood cells
rheumatoid arthritis (RA) an autoimmune disease in which the body's immune system attacks its own connective tissue; characterized by inflammation of the synovial membrane of the joints
salicylates a class of nonnarcotic analgesics that have both pain-relieving and antipyretic (fever-reducing) properties
saline laxatives laxatives that attract water into the hollow portion of the colon, or lumina, and increase intraluminal pressure
secondary diabetes diabetes caused by drugs
secretion the release of cell products, including hydrogen and potassium ions and acids and bases, during urine formation
somatic nervous system the part of the efferent system of the PNS that regulates the skeletal muscles
stable angina a type of angina characterized by effort-induced chest pain from physical activity or emotional stress; usually predictable and reproducible
stress ulcer a peptic ulcer, usually gastric, that occurs in a clinical setting; caused by a breakdown of natural mucosal resistance
surfactants stool softeners that have a detergent activity that facilitates admixture of fat and water to make the stool soft and mushy
systolic blood pressure a blood pressure measurement that measures the pressure during contraction of the heart
testosterone a hormone that is responsible for sperm production, sexual potency, and the maintenance of muscle mass and strength, among other functions
thiazide diuretics diuretics that promote sodium and water excretion in the urine, lower the sodium level in vessel walls, and reduce vasoconstriction
thrombi stationary blood clots
thyroid gland a gland that produces hormones that stimulate various body tissues to increase their activity level
tophi deposits of sodium urate around a joint
type I diabetes insulin-dependent diabetes, in which the pancreas has no ability to produce insulin
type II diabetes a type of diabetes characterized by insulin insufficiency or by the resistance of the target tissues to the insulin produced
ulcerative colitis irritation and inflammation of the large bowel, causing it to look scraped; characterized by bloody mucus leading to watery diarrhea containing blood, mucus, and pus
unstable angina a type of angina characterized by chest pain that occurs with increasing frequency, diminishes the patient's ability to work, and has a decreasing response to treatment; may signal an oncoming MI
uremia the clinical syndrome resulting from renal dysfunction in which excessive products of protein metabolism are retained in the blood
variant angina a type of angina characterized by chest pain due to coronary artery spasm; usually not stress induced
vasomotor affecting blood vessels
very-low-density lipoproteins (VLDLs) lipoproteins containing 60% triglycerides and 12% cholesterol
virilization the development of male characteristics
visceral pain sharp, stabbing pain from the organs
action potential- the electrical signal that contracts muscles
Created by: cindya
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