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quiz 13

pht 101

1 what is typically the first gout affected joint? big toe
2 by what mechanism do muscle relaxants act? both (they prevent neurotransmitter destruction and keeps it from reaching it's receptor)
3 which muscle relaxant acts on benzodiazepine receptors? diazepam (Valium)
4 what prostaglandin molecule facilitates platelet aggregation & is inhibited by low dose (81 to 325 mg) aspirin? thromboxane A2
5 what substance mediate pain, fever, and inflammation? prostaglandins
6 what type of pain is from the skin, muscle, and bone? somatic
7 which drug has antiinflammatory properties? aspirin
8 what neurotransmitter is released at the neuromuscular juction? acetylcholine
9 what drug treats overdose of acetaminophen? acetylcysteine (Mucomyst)
10 how do salicylates reduce fever? they inrease blood flow to the skin
11 which muscle relaxants is a DEA control? diazepam (Valium)
12 why should aspirin be avoided by children? reye syndrome develops in non chicken pox exposed children
13 which is a muscle type? all ( skeletal, smooth, & cardiac)
14 which nonnarcotic analgesic is rx only? choline magnesium trisalicylate (Trilisate)
15 what analgesic binds centrally to opioid receptors & also stops reuptake of norepinephrine (NE) and serotonin (5HT) into nerve endings? tramadol (Ultram)
16 what comes from preventing acetylcholine destruction on skeletal muscle? paralysis by fatigue
17 which type of cyclooxygenase (COX) is released during inflammation & is blocked by celecoxib (Celebrex)? COX 2
18 which drug will least likely produce GI irritation at analgesic doses? celecoxib (Celebrex)
19 which disease modifying antirheumatic drug treats malaria as well as rheumatoid arthritis? hydroxychloroquine (Plaquenil)
20 what is the most serious effect associated with acetaminophen? liver damage
21 what type of cyclooxygenase is associated with inflammatory pain, but no with GI lining protection? COX 2
22 which disease modifying antirheumatic drug treats tumor metastases as well as psoriasis along with rheumatoid arthritis? methotrexate (Rheumatrex)
23 what skeletal muscle relaxant acts directly on skeletal muscle? dantrolene (Dantrium)
24 what effect of nonnarcotic analgesics most commonly limits their use? GI disturbances
25 what daily dose of aspirin is fatal? 10 grams
26 what drug class prevents worsening of rheumatoid arthritis? DMARDs or disease modifying antirheumatic drugs
27 which drug treats gout(y arthritis)? all (allopurinol (Zyloprim), colchicine, & indomethacin (Indocin)
28 what is a lab test for rheumatoid arthritis? ESR (erythrocyte sedimentation rate)
29 nsaids can interact with which drug class? anticoagulants
30 how do nonnarcotic (nonopoid) anagesics cause GI distress? they block synthesis of prostaglandins
31 which drug treats gout and interferes with leucocytes by reducing their mobility and joint phagocytosis? colchicine
32 what clinical (side) effect of aspirin can also be caused by acetaminophen (Tylenol)? fever reduction
33 which isn't a joint type? tophus
34 which statement is for nsaid users? if sensitive to aspirin, avoid nsaids
35 what is a prototype nsaid? aspirin
36 what causes gout? excessive uric acid production or improper excretion
37 when injected, which nsaid is as effective as morphine in pain relief? ketorolac (Toradol)
38 which is a disease modifying antirheumatic drug (DMARD)? all (adalimunab (Humira), anakinra (Kineret), methotrexate (Rheumatrex), & azathioprine (Imuran))
Created by: cindya