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Pharm: Ch 40: Def.
Pharm: Kee Ch 40: Drugs for upper resp disorders: definitions
| Question | Answer |
|---|---|
| Common Cold | Most prevalent form of URI |
| Acute rhinitis | Acute inflammation of mucous membranes of the nose; cause increased nasal secretions |
| Allergic rhinitis | Caused by pollen or a foreign substance; cause increased nasal secretions |
| Rhinorrhea | Watery nasal discharge |
| Antihistamines | H1 blockers, or H1 antagonists, compete w/ histamine for receptor sites, preventing histamine response |
| 1st-Generation Antihistamines | Cause drowsiness, dry mouth, & other anticholinergic symptoms; diphenhydramine (Benadryl)is prototype |
| 2nd-Generation Antihistamines | Fewer anticholinergic symptoms and lower incidence of drowsiness; ceritizine (Zyrtec), fexofenadine (Allegra), loratadine (Claratin), and azelastine (Astelin). |
| Decongestants (sympathomimetic amines) | produce vascular constriction of the capillaries in the nasal mucosa |
| Rebound nasal congestion | Rebound vasodilation resulting from frequent use of decongestants |
| Antitussives | Act on cough-control center in medulla to suppress cough reflex |
| Expectorants | loosen bronchial secretions so they can be eliminated by coughing |
| Sinusitis | Inflammation of mucous membranes of 1 or more of the maxillary, frontal, ethmoid, or sphenoid sinuses |
| Acute pharyngitis | Inflammation of the throat (sore throat); can be caused by virus, beta-hemolytic streptococci, or other bacteria |