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Summative Exam
P3
Question | Answer |
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Oseltamivir is indicated for the I. treatment of influenza II. prophylaxis of influenza III. treatment of respiratory syncytial virus (RSV) | *(C) Oseltamivir (Tamiflu) is an antiviral compound that is used to treat illness caused by influenza in patients 1 year or older. It is only effective if used within 2 days of symptom outbreak. The drug is also indicated for the prophylaxis of influenza |
As an antiarrhythmic drug, mexiletine (Mexitil) is most similar in action to which one of the following agents? (A) amiodarone (B) tocainide (C) digoxin (D) verapamil (E) propranolol | *(B) Tocainide (Tonocard) is most similar to mexiletine (Mexitil). Both are classified as Group IB antiarrhythmic drugs. These are agents that slightly depress phase 0 and may shorten the duration of the action potential. They are most commonly used for t |
The dose of levothyroxine sodium that is approximately equivalent to 25 μg of liothyronine sodium, USP is (A) 0.25 μg (B) 0.4 μg (C) 250 μg (D) 120 μg (E) 100 μg | *(E) Liothyronine sodium (Cytomel) is a synthetic form of the natural thyroid hormone T3. Approximately 100 μg of levothyroxine sodium (T4) is equivalent to 25 μg of liothyronine sodium (T3). |
Which of the following is (are) expected effect(s) of inhaling the smoke of cannabis (marijuana)? I. decreased pulse rateII. perceptual changes III. vascular congestion of the eye | *(D) Upon inhaling the smoke of cannabis (marijuana) perceptual changes, vascular congestion of the eye, and increased heart rate generally occur. These effects generally continue for about 1 to 2 h after smoke inhalation; however, one of cannabis’ active |
Hydralazine is an antihypertensive agent that works by (A) blocking alpha-adrenergic receptors (B) inhibiting ACE (C) directly dilating peripheral blood vessels (D) inhibiting catechol-O-methyltransferase (COMT) (E) blocking beta-adrenergic receptors | *(C) Hydralazine is a direct-acting peripheral vasodilator. Because of its potential for producing a number of serious adverse effects, hydralazine is not a first-choice antihyperten sive agent. Its use has been associated with causing reflex tachycardia |
An agent that would be most likely to cause drug-induced bronchospasm is (A) salmeterol (B) zileuton (C) isoproterenol (D) sotalol (E) cromolyn | *(D) Sotalol (Betapace) is a selective beta-adrenergic blocking agent used for the treatment of life-threatening ventricular arrhythmias. As is the case with all other beta-adrenergic blockers, sotalol should not generally be used in patients with a histo |
Respiratory damage is most likely to occur with the use of which of the following antineoplastic agents? (A) vincristine (B) cytarabine (C) actinomycin (D) bleomycin (E) flutamide | *(D) Bleomycin (Blenoxane) is an antineoplastic drug in the antibiotic group. The most seriousadverse effect associated with this drug is pulmonary fibrosis. About 10% of patients on this drug experience some form of pulmonary toxicity |
The anti-inflammatory effect of NSAIDS is due to their ability to I. reset the hypothalamic “setpoint” II. inhibit the stimulation of the chemoreceptor trigger zone (CTZ) III. inhibit prostaglandin synthesis | *(B) The anti-inflammatory and analgesic action of NSAIDS is believed to result from inhibition of prostaglandin synthesis |
Which one of the following drugs is indicated for the treatment of primary nocturnal enuresis? (A) ritodrine (Yutopar) (B) dicyclomine (Bentyl) (C) desmopressin acetate (DDAVP) (D) metolazone (Zaroxolyn) (E) mannitol (Osmitrol) | *(C) Desmopressin acetate is the synthetic analog of naturally occurring human antidiuretic hormone (ADH) produced by the posterior pituitary gland. It is administered intranasally (Stimate) or orally (DDAVP) for the treatment of primary nocturnal enuresi |