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chpt 8 quiz
pht 101
| Question | Answer |
|---|---|
| which of the following drugs has been shown to improve cognitive function and social behavior of patients with alzheimer disease and is sold over the counter? | ginko |
| what is the drug of choice for status epilepticus and how is it administered? | diazepam (Valium) IV |
| which ADHD/ADD drug has no abuse potential? | atomoxetine (Strattera) |
| which pair of anticonvulsants is most likely to interact with other drugs a patients may be taking? | phenobarbital (Luminal) & phenytoin (Dilantin) |
| what term is used to describe continuous tonic-clonic seizures, lasting over 30 minutes, during which consciousness may not return? | status epilepticus |
| which anticonvulsant reduces the release of glutamate, norepinephrine, & substance P & appears to modulate calcium influx into brain cells? | pregabalin (Lyrica) |
| which of the following anticonvulsants is correctly paired with the process it most likely affects? | diazepam (Valium) - GABA |
| which of the following is not a brand name for methylphenidate? | Adderall |
| which anticonvulsant does not act via GABA receptors and is frequently used to treat neuropathic pain? | gabapentin (Neurontin) |
| what benzodiazepine anticonvulsant is used to treat alcoholic seizures? | lorazepam (Ativan) |
| what is the only drug approved for the amyotrophic lateral sclerosis (ALS)? | riluzole (Rilutek) |
| what 2 neurotransmitter in the brain appear to play the greatest role in seizures? | GABA & glutamate |
| the prevalence of Parkinson disease is highest in what age group? | over 60 |
| what percent of patients with parkinsons develop on-off phenomenon and after how many years of therapy does this averagely happen? | 66% in 5 yrs |
| what anticonvulsant is rapid converted to phenytoin, but because it is water soluble, is better tolerated, with fewer infusion reactions, when injected intravenously? | fosphenytoin (Celebyx) |
| which drug listed below is the first of a new class of anti-Parkinson drug that inhibits catechol-o-methyl transferase (COMT) and is used to enhance levodopa? | entacapone (Comtan) |
| which of the following anticonvulsants is also used to treat manic episodes in bipolar mood disorders? | valproic acid (Depakene) |
| what may occur in the presence or obvious clinical symptoms (e.g., convulsions) | seizures |
| which of the following anticonvulsants is a DEA scheduled controlled substance? | diazepam (Valium) |
| what is the most common extrapyramidal disease? | parkinsons |
| which is not a generalized seizure? | simple partial |
| what dopamine precursor is used to treat patients with parkinsons? | levodopa (Dopar) |
| which anticonvulsant listed below is also used to treat manic episodes in bipolar disorder? | divalproex (Depakote) |
| which drug is used to treat parkinsons? | levodopa (Dopar) |
| which anticonvulsant is used exclusively for absence seizures? | ethosuximide (Zarontin) |
| what drug is used to help diagnose myasthenia gravis? | edrophonium (Enlon) |
| which drug is a potent inhibitor of MAO type B, which is primarily found in the brain? | selegiline (Eldepryl) |
| why do prescribers of anticonvulsants prohibit gererics for seizure patients? | even minor bioavailability changes across preps affect blood concentration |
| which of the following is not a common seizure cause? | hypertension |
| which neurotransmitter is deficient in nigrostriatal pathways of patients Parkinsons disease? | dopamine |
| what combination drug has levodopa & a peripheral levodopa metabolism inhibitor? | Sinemet |