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Mod XI Pharm Charm
Exam #4 Mod 11
| Question | Answer |
|---|---|
| Histamine-1 receptor antagonists | antihistamines |
| 1st generation antihistamines | [Benadryl] diphenhydramine |
| drowsiness, fuzzy vision, dry mouth | SE of 1st generation antihistamines |
| Acute Angle Glaucoma, or BPH because of their anticholinergic effect | CI of 1st generation antihistamines |
| [Allegra] Fexofenadine, Zyrtec, Claritin, little or no drowsiness | 2nd generation antihistamines |
| this secretions so you can increase them stimulate the production of a thin and more fluid mucus more easily expectorated their effectiveness has not been proven | Expectorant [Robitussin] Guaifenesin |
| mucolytic agent used by inhalation with a bronchodilator (causes bronchoconstric) looosen and thin secretions ANTIDOTE: ACETOMINAPHEN poisoning | [Mucomyst] |
| Albuterl [Proventil, Ventolin] given PRN for acute response most selective when given in small doses by inhalation | Short-Acting Beta 2 agonist |
| hyperglycemis (axn on liver) Prolonged Labor (Axn on the uterus) Tremors (Axn on the CNS) | Se of short-acting Beta-2 agonists |
| this drug prevents asthma | Long-acting Beta-2 agonist |
| treats long-term asthma maintenance when used more than once every 12 hours, death has been reported | Salmeterol [Serevent] |
| continued use of this drug causes down regulation of the beta-2 recep should NOT be used as "mono-therapy" for asthma first used as an inhaled steroid | Salmeterol[Serevent] |
| treatment of asthma and reversal of bronchospasm associated with COPD treats apnea in preterm infants | Theophylline (Methylxanthines) |
| readily absorbed after oral, rectal or parenteral admin food may slow but does not decrease absorption of immediate release preps this drug may decrease or increase bioavailability of some sustained release preps | Theophylline pharmacokinetics |
| this drug interacts with: Barbituates Phenytoin Rifampin Thyroid smoking all enzyme inducers that decrease drug blood levels | Theophylline drug interactions |
| palpations, insomnia and jitteriness | First (early) signs of Theophylline toxicity |
| Tachycardia Restlessness Agitation Hypotension | Theophylline toxicity |
| stabilize mast cells prevent release of various chemicals like: histamine, leukotrienes,serotonin that cause edema and inflammation | Corticosteroid |
| anti-inflammatory agents that successfully alleviate Asthma! | Corticosteroids |
| these drugs arfe not bronchodilators restore bronchodilator response to sympathomimetics (hypoxemia) | Corticosteroids |
| Hydrocortisone-Parental Steroid Prednisone-Oral Steroid Systemic Steroid- used in small doses possible for the shortest time Inhalation steroids- [QVAR] commonly prescribed | Corticosteroid drugs used |
| hoarsness monilia- oropharyngeal overgrowth of Candida albicans Headache, cataracts, IO pressure | SE of Inhaled steriods |
| NOT useful in pt experiencing acute bronchospasm reduce inflammation prevent bronchoconstriction caused by inflammation | Inhaled steroid use |
| when changing from oral to inhales: Taper oral dose SLOWLY After clinical dose has been obtained, try to decrease dose to the lowest amount req'd to control symptoms long term use poses risks | Patient advice when using corticosteroids |
| [Intal] Cromolyn Cromolyn and Nedocromil are non-steroidal drugs stabilize mast cellos | Mast Cell Stabilizers uses |
| reduces release of mast cell chemicals bronchoconstriction, edema amd inflammation Prevention/Prophylaxis of asthma attacks | Mast Cell Stabilizers uses Cromolyn [Intal] |
| treats allergic rhinitis Opthamalic solution for ocular allergy symptoms | Mast cell stabilizer uses |
| agents used to decrease the intensity and frequency of coughing episode | Antitussives |
| drugs used for antitussives | Dextromethorphan (DM), Benzonatate[Tessalon] |
| morphine derivative with no analgesic, euphoric or addictive qualities | Dextrometorphan DM |
| local anesthetics absorbed and anesthetizes stretch or cough receptors in the lung relieves cough DO NOT CHEW or DISSOLVE CAPSULES in mouth or they may be anesthetized too | [Tessalon] Benzonatate |
| Nausea and Headache | Expectorant SE |
| used for relief of symptoms of seasonal perennial rhinitis | Intranasal setroids [Flonase] Fluticasone |
| if nasal passages are blocked they should be cleared with topical decongestants first | Intranasal steroids |
| treats allergic rhinitis | Several corticosteroids Azelatine (Antihistamines) Cromolyn nasal spray |
| Oral antihistamines like: [Singulair]Montelukast | treats allergic rhinitis |
| se: cough nasal burning nasal irritation nasal fungal infection pharyngitis angioedema (skin swelling) | Flonase SE |
| bronchoconstriction decrease mucociliary function increase airway edema increase microvascular permeability | Lipoxygenase inhibitor uses |
| [Zyflo]Zileuton Prophylaxis and chronic treatment in adults and kids older than 12 this drug is NOT for acute attacks! | Lipooxygenase inhibitor drugs |
| Urinary retention constipation fuzzy vision dry mouth | Anticholinergic drug adverse effects |
| Beta agonists can stimulate beta-receptors found elsewhere in the body, such as those in large blood vessels (which decreases peripheral resistance), in the liver and/or pancreas causing? heart causing? skeletal muscle causing? | Increased blood glucose Tachycardia Tremors |
| Overdose may cause hyperpyrexia, convulsions or coma. | Antihistamines |
Created by:
boomer_bevo
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