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Pharm2 Lect 3

Pharm2 Beta Blockers

QuestionAnswer
Adrenolytic: Non-selective, competitive, reversible Beta Blockers 1.Propanolol. 2.Nadolol. 3.Timolol. 4.Pindolol. 5.Carteolol. 6.Levobunolol.
Adverse effects to non-selective and selective, competitive, reversible Beta Blockers 1.Bradycardia. 2.AV block. 3.Dec Inotropy & HF. 4.Hypotension. 5.Insomnia & depression. 6.sexual dysfunction. 7.Inc triglycerides. 8.Rebound Hypertension.
Contraindications for selective & non-selective, competitive, reversible Beta blockers 1.Diabetes. 2.Hypoglycemia. 3.Asthma.
What are Non-selective, competetive, reversible Beta blockers used to treat? 1.CV disease. 2.Phenochromocytoma. 3.Glaucoma. 4.Migraine. 5.Tremor. 6.Esophageal Variceal bleeding. 7.Prophylaxis.
Adrenolytic: Non-selective, competitive, reversible Beta Blockers: Propanolol Method of action: 1.Migraine-Prevent arterial dilation, inhibit renin secretion, dec arachidonic acid synthesis and prostaglandin production, may affect serotonin levels. 2.Tremor- b2 receptors on red, slow contracting skeletal muscle: tremor
Adrenolytic: Non-selective, competitive, reversible Beta Blockers: Nadolol Method of action: 1.Migraine-Prevent arterial dilation, inhibit renin secretion, dec arachidonic acid synthesis and prostaglandin production, may affect serotonin levels. 2.Tremor- b2 receptors on red, slow contracting skeletal muscle: tremor
Adrenolytic: Non-selective, competitive, reversible Beta Blockers: Timolol Method of action: 1.Migraine-Prevent arterial dilation, inhibit renin secretion, dec arachidonic acid synthesis and prostaglandin production, may affect serotonin levels. 2.Tremor- b2 receptors on red, slow contracting skeletal muscle: tremor
Adrenolytic: Non-selective, competitive, reversible Beta Blockers: Pindolol Method of action: 1.Tremor-B2 receptors on red, slow contracting skeletol muscle: tremor
Adrenolytic: Non-selective, competitive, reversible Beta Blockers: Carteolol 1.Mech of action: Blocks B2 receptors on skeletal muscle preventing tremors, Dec aq humour production & IOP. 2.Topical-EYE.
Adrenolytic: Non-selective, competitive, reversible Beta Blockers: Levobunolol 1.Mech of action: Blocks B2 receptors on skeletal muscle preventing tremors, Dec aq humour production & IOP. 2.Topical-EYE.
What 3 non-selective, reversible, competitive Beta-blockers are used to treat migraines? 1.Propanonlol. 2.Nadolol. 3.Timolol.
What 2 non-selective, reversible, competitive Beta-blockers are a topical-EYE form? 1.Carteolol. 2.Levobunolol.
Adrenolytic: B1 selective, competitive, reversible Beta Blockers 1.Metoprolol. 2.Atenolol. 3.Acebutolol. 4.Betaxolol. 5.Bisoprolol. 6.Esmolol. **BBEAAMM
What are B1-selective, competitive, reversible Beta Blockers used to treat? 1.CV disease. 2.Phenochromocytoma. 3.OMA (W/ A blocker). 4.Glaucoma. 5.Migraine (Metaprolol & Atenolol). 6.Blurred vision (only betaxolol).
Adrenolytic: B1 selective, competitive, reversible Beta Blockers: Metoprolol Meth of action: 1.Migraine-Prevent arterial dilation, inhibit renin secretion, dec arachidonic acid synthesis and prostaglandin production, may affect serotonin levels.
Adrenolytic: B1 selective, competitive, reversible Beta Blockers: Atneolol Meth of action: 1.Migraine-Prevent arterial dilation, inhibit renin secretion, dec arachidonic acid synthesis and prostaglandin production, may affect serotonin levels.
Adrenolytic: B1 selective, competitive, reversible Beta Blockers: Acebutolol, Bisprolol, & Esmolol B1 selective, competitive, reversible blocker.
Adrenolytic: B1 selective, competitive, reversible Beta Blockers: Betaxolol 1.Mech of action: Dec aq humour proction by ciliary body & Dec IOP. 2.Topical-EYE
Anderolytic: Nebivolol <10mg: B1-selective, >10mg/poor metabolizer: B1&2-selective. 1.Either B1 or B1&2 antagonist that also stimulates endothelial NO activity (VD).
If administering an adrenolytic to a patient with phenochromocytoma, what else must be administered with it? Non-selective Alpha Antagonist. Otherwise you will cause unopposed VC b/c all the Epi produced with activate only A1. **Phentolamine or Phenoxybenzamine.
What 5 beta-blockers are effective in treating migraines? 1.Propanolol. 2.Timolol. 3.Metoprolol. 4.nadolol. 5.atenolol. **Prophylatic treatment (before onset)
What type of beta-blockers would you want to use to treat essential tremor & Esophageal variceal bleeding? NON-SELECTIVE. **esophageal varices caused by cirrhosis of liver.
What effect will Beta-Blockers have Beta receptors? UP regulation.
Is phentolamine used for treatment of ESSENTIAL hypertension? NO, beta-blockers.
What happens with abrupt withdraw from beta-blockers? REBOUND HYPERTENSION. also will se tachycardia, angina, & nervousness.
Created by: WeeG
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