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PharmTech-M5-1
Antiinfectives, Antiinflammatories and Antihistamines
| Question | Answer |
|---|---|
| Nosocomial Infections | Infections acquired within hospitals or healthcare facilities. These infections can be deadly for patients with an already weakened immune system because they are difficult to combat. |
| Protozoa | Human parasite; single celled organism. |
| Viruses do not have the ability to alter their genetic makeup because: | Viruses use their hosts cells and components to assemble it's own blueprints. |
| Alpha Receptors | Located in the peripheral blood vessels; heart and the eyes; on smooth muscle. |
| Beta Receptor - B1 | Receptors located in the heart muscle. |
| Beta Receptors - B2 | Receptors located in the respiratory system. |
| First Generation Antihistamines | Bind to histamine 1 and histamine 2 receptors. Can cause sedation, decrease nausea, vomiting and motion sickness. |
| Second Generation Antihistamines | Effect histamine 1 receptors specifically, therefore causing less sedation. |
| The first antibiotic discovered: | Sulfa - sulfanilamide |
| Discovered by Alexander Fleming: | Penicillin |
| H. Pylori can be treated with: | Septra, Metronidazole, and Tetracycline |
| The most common eye infection: | Conjunctivitis |
| T.B. is caused by a mycobacterium and is treated with: | isoniazid, rifampin, and ethambutol |
| A common fungus that is part of the body's natural flora: | Candida Albicans |
| Third Generation Cephalasporins | Vantin, Cefixime, Ceftizoxime |
| Step one of the invasion and spread of virions | Attachment |
| Step two of the invasion and spread of virions | Injection of nucleic acids |
| Step three of the invasion and spread of virions | Synthesis |
| Step four of the invasion and spread of virions | Assembly |
| Step five of the invasion and spread of virions | Spread via lysis or budding. |
| One way that antiviral agents work against viruses: | Stop the virus from attaching to the host cell by blocking the sites on the virion. |
| One way that antiviral agents work against viruses: | Stop the replication process within the host cell inhibiting the virion from making its necessary components. |
| One way that antiviral agents work against viruses: | Disrupt the assembly of virion particles as they are being assembled within the host cell; rendering an incomplete virion particle. |
| Aminoglycosides are considered dangerous because: | They have a narrow range between therapeutic and toxic serum levels; can cause nephrotixicity or ototoxicity. |
| Resistant microorganisms can be treated with: | Cipro, Vancocin, tigecycline |
| Aspirin can be used to treat: | Inflammation, pain, fever, gout, decrease blood clots, prevent heart attack and stroke, and prevent pulmonary embolism. |
| NSAID Properties: | Analgesic, antipyretic, and antiinflammatory |
| Prednisone should not be discontinued abruptly in order to: | Allow the body to initiate production of glucocorticoids. |
| An induced systemic or generalized sensitivity; immunologic allergic reaction is called: | Anaphylaxis |
| Beta Adrenergics effect the bronchial airways by: | Dilating bronchial muscles. |
| An antiasthmatic and antiallergic agent that can prevent allergic reactions from occurring is: | Cromolyn |
| Antihistamine side effects: | Dizziness, drowsiness, headache, stomach pain, dry mouth, vision changes, and loss of appetite |
| Agents that kill bacteria: | Bacteriocidals |
| Chemical agent that kills or inhibits the growth of bacteria; used to treat infections. | Antibiotic |
| Substance that kills or inhibits the growth of microrganisms. | Antimicrobials |
| Agent that prevents the growth of bacteria but does not kill the microbe. | Bacteriostatics |
| Bacteria unable to keep crystal violet stain when washed in acid alcohol: | Gram Negative organisms |
| Bacteria that are able to keep crystal violet stain when washed in acid alcohol. | Gram Positive organisms |
| Roundworm | Trichinella spiralis (trichinosis) |
| Hookworm | Ancylostoma duodenale/necator americanus |
| Tapeworm | Taenia saginatea, taenia solium |
| Antiviral agent | Acyclovir |
| Mebendazole | Antihelminthic |
| Griseofulvin | Antifungal |
| Rifampin | Antituberculin |
| Ingest dead tissue, bacterial cells, or dying cells | Macrophages |
| Adhere to endothelial cells: intensify inflammation by causing direct cell injury and promoting formation of antibodies that increase inflammatory response. | Lymphocyte |
| Can neutralize or destroy antigens in different ways, such as by coating or lysing antigen; can stimulate phagocytosis and prevent antigen from adhering to host cells. | Antibody |
| Assist in blood coagulation. | Fibrinogen |
| Adhere to damaged site to protect against infection by destroying infectious microbes; also destroy antigens. | Neutrophils |
| Eventually become macrophages; macrophages are part of first-line defense in inflammatory process. | Monocyte |
| These mature leukocyte cells fight infection | Granulocyte |
| These white blood cells are in the bone marrow and fight infection and tissue damage; destroy foreign organisms and also clean up damaged cells by phagocytosos. | Leukocyte |