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PharmTech-M5-1

Antiinfectives, Antiinflammatories and Antihistamines

QuestionAnswer
Nosocomial Infections Infections acquired within hospitals or healthcare facilities. These infections can be deadly for patients with an already weakened immune system because they are difficult to combat.
Protozoa Human parasite; single celled organism.
Viruses do not have the ability to alter their genetic makeup because: Viruses use their hosts cells and components to assemble it's own blueprints.
Alpha Receptors Located in the peripheral blood vessels; heart and the eyes; on smooth muscle.
Beta Receptor - B1 Receptors located in the heart muscle.
Beta Receptors - B2 Receptors located in the respiratory system.
First Generation Antihistamines Bind to histamine 1 and histamine 2 receptors. Can cause sedation, decrease nausea, vomiting and motion sickness.
Second Generation Antihistamines Effect histamine 1 receptors specifically, therefore causing less sedation.
The first antibiotic discovered: Sulfa - sulfanilamide
Discovered by Alexander Fleming: Penicillin
H. Pylori can be treated with: Septra, Metronidazole, and Tetracycline
The most common eye infection: Conjunctivitis
T.B. is caused by a mycobacterium and is treated with: isoniazid, rifampin, and ethambutol
A common fungus that is part of the body's natural flora: Candida Albicans
Third Generation Cephalasporins Vantin, Cefixime, Ceftizoxime
Step one of the invasion and spread of virions Attachment
Step two of the invasion and spread of virions Injection of nucleic acids
Step three of the invasion and spread of virions Synthesis
Step four of the invasion and spread of virions Assembly
Step five of the invasion and spread of virions Spread via lysis or budding.
One way that antiviral agents work against viruses: Stop the virus from attaching to the host cell by blocking the sites on the virion.
One way that antiviral agents work against viruses: Stop the replication process within the host cell inhibiting the virion from making its necessary components.
One way that antiviral agents work against viruses: Disrupt the assembly of virion particles as they are being assembled within the host cell; rendering an incomplete virion particle.
Aminoglycosides are considered dangerous because: They have a narrow range between therapeutic and toxic serum levels; can cause nephrotixicity or ototoxicity.
Resistant microorganisms can be treated with: Cipro, Vancocin, tigecycline
Aspirin can be used to treat: Inflammation, pain, fever, gout, decrease blood clots, prevent heart attack and stroke, and prevent pulmonary embolism.
NSAID Properties: Analgesic, antipyretic, and antiinflammatory
Prednisone should not be discontinued abruptly in order to: Allow the body to initiate production of glucocorticoids.
An induced systemic or generalized sensitivity; immunologic allergic reaction is called: Anaphylaxis
Beta Adrenergics effect the bronchial airways by: Dilating bronchial muscles.
An antiasthmatic and antiallergic agent that can prevent allergic reactions from occurring is: Cromolyn
Antihistamine side effects: Dizziness, drowsiness, headache, stomach pain, dry mouth, vision changes, and loss of appetite
Agents that kill bacteria: Bacteriocidals
Chemical agent that kills or inhibits the growth of bacteria; used to treat infections. Antibiotic
Substance that kills or inhibits the growth of microrganisms. Antimicrobials
Agent that prevents the growth of bacteria but does not kill the microbe. Bacteriostatics
Bacteria unable to keep crystal violet stain when washed in acid alcohol: Gram Negative organisms
Bacteria that are able to keep crystal violet stain when washed in acid alcohol. Gram Positive organisms
Roundworm Trichinella spiralis (trichinosis)
Hookworm Ancylostoma duodenale/necator americanus
Tapeworm Taenia saginatea, taenia solium
Antiviral agent Acyclovir
Mebendazole Antihelminthic
Griseofulvin Antifungal
Rifampin Antituberculin
Ingest dead tissue, bacterial cells, or dying cells Macrophages
Adhere to endothelial cells: intensify inflammation by causing direct cell injury and promoting formation of antibodies that increase inflammatory response. Lymphocyte
Can neutralize or destroy antigens in different ways, such as by coating or lysing antigen; can stimulate phagocytosis and prevent antigen from adhering to host cells. Antibody
Assist in blood coagulation. Fibrinogen
Adhere to damaged site to protect against infection by destroying infectious microbes; also destroy antigens. Neutrophils
Eventually become macrophages; macrophages are part of first-line defense in inflammatory process. Monocyte
These mature leukocyte cells fight infection Granulocyte
These white blood cells are in the bone marrow and fight infection and tissue damage; destroy foreign organisms and also clean up damaged cells by phagocytosos. Leukocyte
Created by: mchenderson
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