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PHM1810 Ch 6 Drugs
Pharmacology I: Chapter 6 (ANS Drug Therapy) (Drugs, Entire) De More
| Question | Answer |
|---|---|
| nicotinic N | cholinergic receptor; found in all ANS ganglia and adrenal medulla |
| nicotinic M | cholinergic receptor; found in neuromuscular junction; contacts skeletal muscle |
| muscarinic | cholinergic receptor; found in eyes, heart, lungs, GI tract, sweat glands, urinary bladder, sex organs, blood vessels; contracts pupils, decrease heart rate, constriction, salivation, sweating, relaxation of smooth muscle, vasodialation |
| alpha 1 | adrenergic receptor; found in eyes, arteries, veins, male sex organs, prostate capsule, bladder; constriction, ejaculation causes pupil dilation |
| alpha 2 | adrenergic recpetor; found in presynaptic nerve terminals; inhibition of transmitter release |
| beta 1 | adrenergic receptor; found in heart and kidneys; increased rate and force of contraction renin release |
| beta 2 | adrenergic receptor; found in arterioles of the heart, lungs, skeletal, muscles of the bronchi uterus skeletal, liver; dilation relaxation and increased contraction |
| Proventil | albuterol (sympathomimetic/adrenergic) |
| Dobutrex | dobutamine (sympathomimetic/adrenergic) |
| Intropin | dopamine (sympathomimetic/adrenergic) |
| EpiPen | epinephrine (sympathomimetic/adrenergic) |
| Isuprel | isoproterenol sulfate (sympathomimetic/adrenergic) |
| Alupent | metaproterenol (sympathomimetic/adrenergic) |
| Aldomet | methyldopa (sympathomimetic/adrenergic) |
| Levarterenol | norepinephrine bitartrate (sympathomimetic/adrenergic) |
| Afrin | oxymetazoline (sympathomimetic/adrenergic) |
| Neo-synephrine | phenylephrine hcl (sympathomimetic/adrenergic) |
| Sudafed | pseudoephedrine hcl (sympathomimetic/adrenergic) |
| Yutopar | ritodrine (sympathomimetic/adrenergic) |
| Serevent | salmeterol xinafoate (sympathomimetic/adrenergic) |
| Brethine | terbutaline sulfate (sympathomimetic/adrenergic) |
| Sectral | acebutolol (sympatholytic/adrenergic blocker) |
| Tenormin | atenolol (sympatholytic/adrenergic blocker) |
| Cartrol | carteolol (sympatholytic/adrenergic blocker) |
| Coreg | carvedilol (sympatholytic/adrenergic blocker) |
| Cardura | doxazosin (sympatholytic/adrenergic blocker) |
| Brevibloc | esmolol hcl (sympatholytic/adrenergic blocker) |
| Lopressor | metoprolol tartrate (sympatholytic/adrenergic blocker) |
| Corgard | nadolol (sympatholytic/adrenergic blocker) |
| Regitine | phentolamine (sympatholytic/adrenergic blocker) |
| Minipress | prazosin hcl (sympatholytic/adrenergic blocker) |
| Inderal | propranolol hcl (sympatholytic/adrenergic blocker) |
| Betapace | sotalol hcl (sympatholytic/adrenergic blocker) |
| Flomax | tamsulosin hcl (sympatholytic/adrenergic blocker) |
| Hytrin | terazosin (sympatholytic/adrenergic blocker) |
| Timoptic | timolol maleate (sympatholytic/adrenergic blocker) |
| Urecholine | bethanechol chloride (parasympathomimetics/cholinergic) |
| Evoxac | cevimeline hcl (parasympathomimetics/cholinergic) |
| Prostigmin | neostigmine (parasympathomimetics/cholinergic) |
| Antilirium | physostigmine salicylate (parasympathomimetics/cholinergic) |
| Isopto Carpine / Salagen | pilocarpine hcl (parasympathomimetics/cholinergic) |
| Mestinon | pyridostigmine (parasympathomimetics/cholinergic) |
| Exelon | rivastigmine tartrate (parasympathomimetics/cholinergic) |
| Cognex | tacrine (parasympathomimetics/cholinergic) |
| Mechanism of Action: Sympathomimetics | stimulate alpha 1 and beta 2 receptor sites in smooth muscle of blood vessels, GI tract and genitourinary tract. Produce increased contractility in heart (beta-1) and bronchodialation (beta-2) |
| Adverse Effects: Sympathomimetics | alpha: necrosis, hypertension; beta: headaches, tremors, nervousness, fatigue, hypertension, nausea, vomitting, SOB |
| Mechanism of Action: Sympatholytics | reduce delivery of catecholamines (sympathetic mimicing chemical compounds) to the adrenergic receptors |
| Adverse Effects: Sympatholytics | orthostatic hypotension, edema, headaches, dizziness, somnolence, fatigue, anxiety, pain, nausea, vomiting, diarrhea |
| Indications: Sympathomimetics | hypotension, nasal decongestion, dilation of pupils, adjuncts to anesthesia to reduce bleeding |
| Indications: Sympatholytics | hypertension, dysrhythmias, angina, heart failure, glaucoma, migraines |
| Mechanism of Action: Parasympathomimetics | increase concentration of acetylcholine at transmission sites, prolonging their actions; also: some produces reversible cholinesterase (an enzyme that splits acetylcholine into acetic acid and choline) inhibition |
| Indications: Parasympathomimetics | glaucoma, atonic constipation (form loss of muscle tone), intestinal ileus (blockage), urinary retention, dysrhythmias, Alzheimer's disease |
| Adverse Effects: Parasympathomimetics | flushing, sweating, abdominal cramps, headache, GI distress, diarrhea, colic, nausea/vomiting |
| Mechanism of Action: Parasympatholytics | selectively block all muscarine (a parasympathetic receptor) responses to ACH (excitatory or inhibitory); depresses CNS and relieve rigidity and tremors (i.e. in Parkinson's) |
| Indications of Parasympatholytics | Adjunct treatment in GI disorders (IBS, peptic ulcers, spastic disorders); dilation of the eye, paralysis of the ciliary (eyelid)muscles of the eye, inflammation of the iris; also used in general anesthesia, bradycardia and asystole (lack of heartbeat) |
| Adverse Effects: Parasympatholytics | headache, ataxia |
Created by:
MrsAFlaherty
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