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Pharm I - Part 3.2

Antihyperlipidemic

QuestionAnswer
Use: Elevated LDL cholesterol Cholestryamine, Colesevelam, Colestipol (CHOL/COL)
HyperTRIGlyceridema Gemfibrozil, Fenobirate
HyperLIPIdemia niacin, ezetimibe, HMG-COA Reductase inhibtors
ADE: MYOPATHY Gemfbrozil
D/D: with SATIN -> MYOPATHY, increase WARFARIN effects. Gemibrozil
D/D: avoid use with REPAGLINIDE ITRACONAZOLE Gemibrozil
ADE: PEPTIC ULCER, glucose control difficult in DIABETICS Niacin
D/D: Ethanol causes headaches. Caution with anticoagulants, antiHTN, statins, VASOACTIVE drugs Niacin
ADE: dose related HEPATO-TOXICITY Fenofibrate
D/D: Satins, increase WARFARIN effect Fenobirate
ADE: Myalgia, hepatic, GI Ezetimibe
D/D: STATINS Ezetimibe
ADE: rhabdoMYOLYSIS HMG-COA reducatse Inhibitors "statins"
D/D:HEPATOTOXICITY, RhabdoMYOLYSIS with other lipid lowering meds HMG- COA reductase inhibitors
ADE: Mylagia (achness of muscles WITHOUT excerise) Fenofibrate/ Ezetimibe
"--Statins" HMG- COA reductase
Adivcor (ANL) (niacin + lovastatin) lipid lowering drug
Caduet (CAA) (amlodipine + atovarstatin) lipid lowering drug
Vytorin (VSE) (simvastatin + ezetimibe) lipid lowering drug
Created by: anguyen.2014
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