Question 1

Human Variability Age
The Elderly?

Accepted Answer

lower cardiac output tends to slow the distribution of drugs.

Question 2

Human Variability 
Gender?

Accepted Answer

WOMEN and MEN handle drugs differently.

Question 3

Human Variability 2
Genetics?

Accepted Answer

Determines type and amounts of proteins produced in the body.

Question 4

Human Variability 3
Pharmacognetics?

Accepted Answer

Defines the study of the hereditary basis of individual difference.

Question 5

Human Variability 4
Body Weight?

Accepted Answer

Importance in dosing medication to children?

Question 6

Human Variability 5
Psychological factors?

Accepted Answer

Influences patients responses to drugs, e.g placebo effects can be due to these factors.

Question 7

Diseases that affect drug disposition
Cirrhosis?

Accepted Answer

A chronic and potentially fatal liver disease causing loss of function and resistance to blood flow through the LIVER.

Question 8

Diseases that affect drug disposition 2
Acute viral hepatitis?

Accepted Answer

A systematic infection caused by a virus that causes inflammation of the LIVER.

Question 9

Renal Diseases
Drugs such as Ibuprofen?

Accepted Answer

can cause renal failure

Question 10

Thyroid Diseases
Hypothyroidism?

Accepted Answer

is a condition in which the thyroid hormone secretion is BELOW normal.

Question 11

Thyroid Disease 2
Hyperthyroidism?
Thyroid Disease

Accepted Answer

is a condition in which the thyroid hormone secretions is ABOVE normal.

Question 12

Common Adverse Drug Reactions
idiosyncrasy?

Accepted Answer

UNEXPECTED REACTION to a drug the first time it is taken. generally due to genetic course

Question 13

Common Adverse Drug Reactions 2
Hepatotoxicity?

Accepted Answer

toxic to the liver. Occurs with "APAP, (TYLENOL), ACETAMINOPHEN, ISONIAZIDE

Question 14

Hypersensitive or Allergy
Hypersensitivity?

Accepted Answer

An abnormal SENSITIVITY generally resulting in an allergic reaction.

Question 15

Hypersensitive or Allergy 2
Anaphylactic shock?

Accepted Answer

potentially FATAL hypersensitivity reaction producing severe respiratory distress and cardiovascular collapse.

Question 16

Common Adverse Drug Reactions 3
Teratogenicity?

Accepted Answer

the ability of a substance to cause abnormal fetal development when given to pregnant women. Thyroid

Question 17

Common Adverse Drug Reactions 4
Hematological effect?

Accepted Answer

e.g, Anticoagulants can cause excessive bleeding. BLOOD, coagulation, bleeding, and bone marrow disorder.

Question 18

Common Adverse Drug Reactions 5
Carcinogenicity?

Accepted Answer

Is the ability of a substance to cause cancer. Some ANTICANCER drugs are considered carcinogenic

Question 19

Drug-Drug Interactions
Addictive Effect?

Accepted Answer

Occurs when two drugs with similar pharmacological actions are taken and the effect is equal to that of each drug take alone. the sum of the individual effects.

Question 20

Drug-Drug Interactions 2
Potentiation?

Accepted Answer

Occurs when one drug

Question 21

Drug-Drug Interactions 
Synergism?

Accepted Answer

Occurs when two drugs with different sites or  MECHANISMS of action produce greater effects when taken together than when take alone.

Question 22

Drug-Drug Interactions 2
Antidote?

Accepted Answer

A particular drug given that ANTAGONIZES the toxic effect of another drug.

Question 23

Drug-Drug Interactions 3
Displacement?

Accepted Answer

When one drug is MOVED from protein binding sites by a second drug and the result in increased effects of the displaced drug.

Question 24

Drug-Drug Interactions 4
Inhibition?

Accepted Answer

One drug BLOCKS the activity of metabolic enzymes in the liver.

Question 25

Drug-Diet Interaction

Accepted Answer

When elements of ingested NUTRIENTS interact with a drug affecting the disposition of the drug.

Question 26

Terms to Remember
MAO inhibitors?

Accepted Answer

may interact with some foods may result in severe hypertension and intracraninal hemorrhage.

Question 27

Terms to Remember 2
Heptic Disease

Accepted Answer

also known as liver disease

Question 28

Terms to Remember 3
2D6?

Accepted Answer

occurs in the liver.

Question 29

Terms to Remember 4
Physiological dependence

Accepted Answer

When a patient gets unpleasant PHYSICAL withdrawal symptoms when a dose of a drug is discontinued or reduced.

Mod 4 Week 4

PT chapter 11 review

Question	Answer
Human Variability Age The Elderly?	lower cardiac output tends to slow the distribution of drugs.
Human Variability Gender?	WOMEN and MEN handle drugs differently.
Human Variability 2 Genetics?	Determines type and amounts of proteins produced in the body.
Human Variability 3 Pharmacognetics?	Defines the study of the hereditary basis of individual difference.
Human Variability 4 Body Weight?	Importance in dosing medication to children?
Human Variability 5 Psychological factors?	Influences patients responses to drugs, e.g placebo effects can be due to these factors.
Diseases that affect drug disposition Cirrhosis?	A chronic and potentially fatal liver disease causing loss of function and resistance to blood flow through the LIVER.
Diseases that affect drug disposition 2 Acute viral hepatitis?	A systematic infection caused by a virus that causes inflammation of the LIVER.
Renal Diseases Drugs such as Ibuprofen?	can cause renal failure
Thyroid Diseases Hypothyroidism?	is a condition in which the thyroid hormone secretion is BELOW normal.
Thyroid Disease 2 Hyperthyroidism? Thyroid Disease	is a condition in which the thyroid hormone secretions is ABOVE normal.
Common Adverse Drug Reactions idiosyncrasy?	UNEXPECTED REACTION to a drug the first time it is taken. generally due to genetic course
Common Adverse Drug Reactions 2 Hepatotoxicity?	toxic to the liver. Occurs with "APAP, (TYLENOL), ACETAMINOPHEN, ISONIAZIDE
Hypersensitive or Allergy Hypersensitivity?	An abnormal SENSITIVITY generally resulting in an allergic reaction.
Hypersensitive or Allergy 2 Anaphylactic shock?	potentially FATAL hypersensitivity reaction producing severe respiratory distress and cardiovascular collapse.
Common Adverse Drug Reactions 3 Teratogenicity?	the ability of a substance to cause abnormal fetal development when given to pregnant women. Thyroid
Common Adverse Drug Reactions 4 Hematological effect?	e.g, Anticoagulants can cause excessive bleeding. BLOOD, coagulation, bleeding, and bone marrow disorder.
Common Adverse Drug Reactions 5 Carcinogenicity?	Is the ability of a substance to cause cancer. Some ANTICANCER drugs are considered carcinogenic
Drug-Drug Interactions Addictive Effect?	Occurs when two drugs with similar pharmacological actions are taken and the effect is equal to that of each drug take alone. the sum of the individual effects.
Drug-Drug Interactions 2 Potentiation?	Occurs when one drug
Drug-Drug Interactions Synergism?	Occurs when two drugs with different sites or MECHANISMS of action produce greater effects when taken together than when take alone.
Drug-Drug Interactions 2 Antidote?	A particular drug given that ANTAGONIZES the toxic effect of another drug.
Drug-Drug Interactions 3 Displacement?	When one drug is MOVED from protein binding sites by a second drug and the result in increased effects of the displaced drug.
Drug-Drug Interactions 4 Inhibition?	One drug BLOCKS the activity of metabolic enzymes in the liver.
Drug-Diet Interaction	When elements of ingested NUTRIENTS interact with a drug affecting the disposition of the drug.
Terms to Remember MAO inhibitors?	may interact with some foods may result in severe hypertension and intracraninal hemorrhage.
Terms to Remember 2 Heptic Disease	also known as liver disease
Terms to Remember 3 2D6?	occurs in the liver.
Terms to Remember 4 Physiological dependence	When a patient gets unpleasant PHYSICAL withdrawal symptoms when a dose of a drug is discontinued or reduced.

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