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CH 45: Vasodilators

Vasodilators

QuestionAnswer
do vasodilators act on arteries, veins or both? Vasodilators can act on Arteries, Veins or both
What are the indications for Vasodilators? HTN HTN crisis Angina Heart Failure MI Pheochromocytoma
What is the mechanism of action for vasodilators? vasodilators decrease the afterload by dilating the aorta vasodilators decrease preload because the size of the vessel is increased.
What are the adverse effects of vasodilators? if acting on veins: Orthostatic hypotension can be an adverse effect of vasodilators reflex tachycardia can occur which is related to the dilation and decreased arterial pressure expansion of volume can be a side effect of vasodilators.
Vasodilators can cause expansion of blood volume (related to the body's compensation to dilation) what is often coadministered with vasodilators? vasodilators are frequently administered with diruetics to offload some of the extra fluid
Name the 2 vasodilators: Hydralazine Sodium Nitroprusside
Does hydralazine act on arteries, veins or both? Hydralazine acts on arterioles ONLY!
What does hydralazine do? hydralazine decreasess peripheral resistance.
what are the indications for hydralazine? HTN, HTN crisis, Heart failure
What are the adverse effects of Hydralazine? Hydralazine can cause Rflx tachycardia increased blood volume (administered with diuretic) Systemic Lupus Erythematosus-like symptoms (joint pain, myalgia, butterfly rash on face) Headache, dizziness, flushing
What is done for the patient who is suffering systemic lupus erythematosus-like symptoms (as an adverse effect of hydralazine)? DC med
Which medication can cause systemic lupus erythematosus-like symptoms? hydralazine
Does Sodium Nitroprusside act on Arterioles, veins, or both? Both
What are the indications for Sodium Nitroprusside? Sodium Nitroprusside is the drug of choice for HTN crisis. it is the fastest acting HTN drug.
What is the route of administration of Sodium Nitroprusside? ONLY IV infusion
What is the onset of sodium Nitroprusside? IMMEDIATE
What are the adverse effects of sodium nitroprusside? Excessive hypotension cyanide poisening
how longdoes it take for sodium nitroprusside to eliminate from the body? 72 hours
Created by: 1398660434
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