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Pharm Flash ch. 14

CNS and related stimulant drugs

QuestionAnswer
Amphetamines The collective term for a class of stimulant drugs that includes the originally synthesized drug amphetamine sulfate and all of its drug derivatives.
Analeptics Central nervous system (CNS) stimulants that have generalized effects on the brainstem and spinal cord which in turn produce an increase in responsiveness to external stimuli and stimulate respiration.
Anorexiants Drugs used to control or suppress appetite.
Attention deficit hyperactivity disorder (ADHD) A syndrome affecting children, adolescents, and adults characterized by difficulty in maintaining concentration on a given task and/or hyperactive behavior. The term attention deficit disorder (ADD) has been absorbed under this broader term.
Cataplexy A condition characterized by abrupt attacks of muscular weakness and hypotonia triggered by an emotional stimulus such as joy, laughter, anger, fear, or surprise. It is often associated with narcolepsy.
CNS stimulants Drugs that stimulate specific areas of the brain or spinal cord.
Ergot alkaloids Drugs that have been found to narrow or constrict blood vessels in the brain and provide relief of pain for certain migraine headaches.
What is the primary site of action for serotonin agonists? Cerebrovascular system
What is the primary site of action for AMPHETAMINES PHENIDATES MAZINDOL & MODAFIN Cerebral Cortex
What is the primary site of action for ANOREXIANTS: Hypothalamic and limbic regions.
What is the primary site of action for ANALEPTICS? Medula and Brainstem.
Drugs associated with amphetamines/related stimulants: dextroamphetamine methamphetamine benzphetamine methylphenidate dexmethylphenidate pemoline mazindol
Drugs associated with serotonin agonists: almotriptan, eletriptan, frovatriptan, naratriptan, rizatriptan, sumatriptan, zolmitriptan
Drugs associated with SYMPATHOMIMETICS phentermine, phendimetrazine
Drugs associated with XANTHINES caffeine, theophylline, aminophylline
MISC stimulant drugs: modafinil, sodium oxybate (CNS depressant), sibutramine (anorexiant), orlistat (lipase inhibitor), doxapram (analeptic)
What is the primary site of action for serotonin agonists? Cerebrovascular system
What is the primary site of action for AMPHETAMINES PHENIDATES MAZINDOL & MODAFIN Cerebral Cortex
What is the primary site of action for ANOREXIANTS: Hypothalamic and limbic regions.
What is the primary site of action for ANALEPTICS? Medula and Brainstem.
Drugs associated with amphetamines/related stimulants: dextroamphetamine methamphetamine benzphetamine methylphenidate dexmethylphenidate pemoline mazindol
Drugs associated with serotonin agonists: almotriptan, eletriptan, frovatriptan, naratriptan, rizatriptan, sumatriptan, zolmitriptan
Drugs associated with SYMPATHOMIMETICS phentermine, phendimetrazine
Drugs associated with XANTHINES caffeine, theophylline, aminophylline
MISC stimulant drugs: modafinil, sodium oxybate (CNS depressant), sibutramine (anorexiant), orlistat (lipase inhibitor), doxapram (analeptic)
Avoid Ginko use with: Warafin, aspirin
Avoid Ginsing use with: Diabetic drugs to lower bloodsugar (insulin, etc)
Avoid using Guarana with: Adenosine, disulfiram, quinolones, oral contraceptives, beta-blockers, iron, lithium, phenylephrine (e.g., nasal spray), cimetidine, theophylline, tobacco
The actions of stimulants mimic those of: The neurotransmiters of the symphathatic nervous system NOREPINEPHRINE DOPAMINE AND SEROTONIN.
serotonin agonists may be administered by: subcu injection, nasal spray, oral tablet
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