Save
Busy. Please wait.
Log in with Clever
or
show password
Forgot Password?
Don't have an account?  Sign up 
Sign up using Clever
or
Username is available taken
show password


Make sure to remember your password. If you forget it there is no way for StudyStack to send you a reset link. You would need to create a new account. Your email address is only used to allow you to reset your password. See our Privacy Policy and Terms of Service.

Already a StudyStack user? Log In

Reset Password
Enter the associated with your account, and we'll email you a link to reset your password.
focusNode
Didn't know it?
click below
 
Knew it?
click below
Don't Know
Remaining cards (0)
Know
0:00
edit
Embed Code - If you would like this activity on your web page, copy the script below and paste it into your web page.

  Normal Size     Small Size show me how

Alzheimers: Pharm

Pharmacology of Alzheimer's disease

QuestionAnswer
What is the etiology of Alzheimer's Disease? ACh is down (90% by the time symptoms occur) Neurofibrillary Tangles Neuritic Plaques
what is an early symptom of Alzheimer's DIsease? Impaired Judgement
What is the action of Cholinesterase inhibitors? These AD drugs inhibit the breakdown of ACh which leads to increased levels of ACh
name 4 Cholinesterase inhibitors Tacrine DOnepezil galantamine rivastigmine
which of the cholinesterase inhibitors are very risky to the liver? Tacrine
What tests monitor liver function? AST ALT Albumin Partial protein Total protein
What are the adverse effects of Cholinesterase inhibitors? n/v/d dyspepsia dizziness headache bronchoconstriction
who should be cautioned when using cholinesterase inhibitors? people with Asthma/COPD because an adverse effect can be bronchoconstriction
what is dyspepsia? metallic taste in mouth
What type of drug is Tacrine? Cholinesterase inhibitor
what is the mechanism of action for Tacrine? reversable inhibition of the enzyme that breaks down ACh
what route is tacrine admninistered? orally
what is a downfall of tacrine? it must be administered q6h which is difficult for people to comply to, especially patients suffering from Alzheimer's Disease
What is Donepezil? A Cholinesterase inhibitor
what is the advantage of Donepezil? it has a longer half life (doesn't have to be administered as often) No risk to liver
what is the mechanism of action of donepezil? same as tacrine reversable inhibition of the enzyme that breaks down ACh
what is the major side effects of donepezil? n/v/d
What is memantine? an NMDA receptor antagonist
what is the mechanism of action of memantine? prevents excess calcium influx. calcium in high amounts intracellularly can impair memory and learning
metabolism and excretion of memantine: not metabolized excreted in urine
How does estrogen help in AD? it doesn't
what are the effects of NSAIDS on AD? decreases incidence by 80%
Fact: Gingko Bilopa helps AD true
Created by: 1398660434
Popular Pharmacology sets

 

 



Voices

Use these flashcards to help memorize information. Look at the large card and try to recall what is on the other side. Then click the card to flip it. If you knew the answer, click the green Know box. Otherwise, click the red Don't know box.

When you've placed seven or more cards in the Don't know box, click "retry" to try those cards again.

If you've accidentally put the card in the wrong box, just click on the card to take it out of the box.

You can also use your keyboard to move the cards as follows:

If you are logged in to your account, this website will remember which cards you know and don't know so that they are in the same box the next time you log in.

When you need a break, try one of the other activities listed below the flashcards like Matching, Snowman, or Hungry Bug. Although it may feel like you're playing a game, your brain is still making more connections with the information to help you out.

To see how well you know the information, try the Quiz or Test activity.

Pass complete!
"Know" box contains:
Time elapsed:
Retries:
restart all cards