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pht 101 c5p8

chapter 5 part 8

QuestionAnswer
The Result of Protease Inhibitors (PIs) is the production of immature, noninfectious virions
Protease Inhibitors (PIs) is Combined with other antiretroviral drugs
Protease Inhibitors (PIs) amprenavir (Agenerase), atazanavir (Reyataz), darunavir (Prezista), fosamprenavir (Lexiva), indinavir (Crixivan), nelfinavir (Viracept), ritonavir (Norvir), saquinavir (Fortovase, Invirase), & tipranavir (Aptivus)
indinavir (Crixivan) should be taken on an empty stomach
Do not take indinavir (Crixivan) with St. John’s wort, Grapefruit juice, or With food, especially high-fat
to take indinavir (Crixivan) take 48 ounces/day of water (kidney stones), Package with a desiccant, & Patient to store in original container
nelfinavir (Viracept) Can cause diarrhea but Loperamide and calcium carbonate can help control
Take nelfinavir (Viracept) with food
ritonavir (Norvir) Increases serum concentrations and decreases dosage frequency of other PIs
ritonavir (Norvir) is Given at a low dose
ritonavir (Norvir) should be Taken with food, has Many side effects, and should be Store in refrigerator
tipranavir (Aptivus) May have some advantages over other PIs because they’re More adaptable structure to protease binding sites
Delivery system improves dissolution and bioavailability of drug
ritonavir (Norvir) are Given with ritonavir (Norvir) as boost
the Black Box warning with ritonavir (Norvir) is to avoid sun exposure
How do fusion inhibitors represent an advance in the treatment of HIV? Prevents AIDS virus from entering the cell
Fusion Inhibitors and Chemokine Coreceptors Prevent HIV from entering immune cells
Fusion Inhibitors enfuvirtide (Fuzeon)
Created by: moekah
Popular Pharmacology sets

 

 



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