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CMB - Chapters 13A
CMB - Chapter13A - Diabetes Meds
| Question | Answer |
|---|---|
| Type I Diabetes (Type I DM) | REQUIRES INSULIN!!! Insulin deficiency from destroyed pancreatic beta cells, which make the insulin |
| Type II Diabetes (Type II DM) | Insulin resistance from decreased receptor sensitivity to insulin |
| Mild hyperglycemia | 126-200 mg/dL |
| Moderate hyperglycemia | 200-300 mg/dL |
| Severe hyperglycemia | 300-500 mg/dL |
| Very severe hyperglycemia | > 500 mg/dL |
| Meglitinides end in | "glinide" |
| Thiazolidinediones (TZDs) end in | "glitazone" |
| Insulin MOA is | aids in storage of glucose to be used for energy later |
| Sulfonylureas MOA is | increases insulin secretion |
| Meglitinides MOA is | increases insulin secretion |
| Biguanides MOA is | Increases insulin sensitivity |
| Thiazolidinediones (TZDs) MOA is | Increases insulin sensitivity |
| Alpha-glucosidase inhibitor MOA is | Inhibits the enzyme that breaks down sucrose |
| DPP-IV inhibitor MOA is | Inhibits the enzyme that breaks down incretins |
| Incretin mimetic MOA is | Increases insulin secretion |
| Aspart | (NovoLog); Rapid-acting insulin |
| Glulisine | (Apidra); Rapid-acting insulin |
| Lispro | (Humalog); Rapid-acting insulin |
| Regular | (Novolin R, Humulin R); short-acting insulin |
| Lente | (Novolin L, Humulin L); intermediate-acting insulin |
| Isophane (NPH) | (Novolin N, Humulin N); intermediate-acting insulin |
| Glargine | (Lantus); Long-acting insulin |
| Detemir | (Levemir); Long-acting insulin |
| Ultralente | (Novolin U, Humulin U); Long-acting insulin |
| Lispro protamine & lispro | (Humalog 75/25); Combination (pre-mixed) insulin |
| Aspart protamine & aspart | (NovoLog 70/30); Combination (pre-mixed) insulin |
| NPH & Regular | (Novolin 70/30, Humulin 70/30); Combination (pre-mixed) insulin |
| Glmepiride | (Amaryl); Sulfonylureas; diabetes medication |
| Glipizide | (Glucotrol); Sulfonylureas; diabetes medication |
| Glyburide | (DiaBeta, Micronase); Sulfonylureas; diabetes medication |
| Repaglinide | (Prandin); Meglitinides; diabetes medication |
| Nateglinide | (Starlix); Meglitinides; diabetes medication |
| Metaformin | (Glucophage); Biguanides; diabetes medication |
| Pioglitazone | (Actos); TZDs; diabetes medication |
| Rosiglitazone | (Avandia); TZDs; diabetes medication |
| Acarbose | (Precose); Alpha-glucosidase inhibitor; diabetes medication |
| Miglitol | (Glyset); Alpha-glucosidase inhibitor; diabetes medication |
| Sitagliptin | (Januvia); DPP-IV inhibitor; diabetes medication |
| Exenatide | (Byetta); Incretin mimetic; diabetes medication |
Created by:
cbowers101
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