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pht 101 c5p6

chapter 5 part 6

QuestionAnswer
zanamivir (Relenza) is Used for influenza A and B
zanamivir (Relenza) Taken within 48 hours of onset of symptoms with 2 inhalations daily, 12 hour intervals, for 5 days
If using bronchodilator, use immediately prior to administration of zanamivir
zanamivir (Relenza) is Sometimes prophylactic
ganciclovir (Vitrasert) is a Ophthalmic antiviral
ganciclovir (Vitrasert) is Available in oral and IV form
Pregnant women should not handle this ganciclovir (Vitrasert) and there’s a chemo precaution
virus a minute infectious agent that does not have all the components of a cell and thus can replicate only within a living host cell
virion an individual viral particle capable of infecting a living cell; consists of nucleic acid surrounded by a capsid (protein shell)
capsid a protein shell that surrounds and protects the nucleic acid within a virus particle
envelope membrane around the capsid in some viruses & carrying surface proteins that attach to cell surface receptors
naked virus a virus without an envelope covering the capsid
flu a common viral infection; influenza
hepatitis a disease of the liver that causes inflammation, can be acute or chronic, and has several forms A-G
human immunodeficiency virus (HIV) a retrovirus transmitted in body fluids that causes AIDS by attacking T lymphocytes
acute viral infection an infection that quickly resolves with no latent infection
chronic viral infection an infection that has a protracted course with long periods of remission interspersed with recurrence
slow viral infection an infection that maintains a progressive course over months or years with cumulative damage to body tissues, ultimately ending in the host's death
local viral infection an infection affecting tissues of a single system such as the respiratory tract, eye, or skin
generalized viral infection an infection that spreads to other tissues by way of the bloodstream or the central nervous system
latency the ability of a virus to lie dormant and then, under certain conditions, reproduce and again behave like an infective agent, causing cell damage
immunoglobulin an antibody that may prevent an organism from attaching to a cell receptor and may destroy the organism
interferon a substance that exerts virus-nonspecific but host-specific antiviral activity by inducing gene coding for antiviral proteins that inhibit the synthesis of viral RNA
vaccination the introduction of a vaccine, a component of an infectious agent, into the body to produce immunity to the actual agent
antiviral agents that prevent virus replication in a host cell without interfering with the host's normal function
prodrug a compound that on administration and chemical conversion by metabolic processes becomes an active pharmacological agent
HIV is a retrovirus which Copies its RNA genetic information into the host’s DNA, Uses reverse transcriptase, a retroviral enzyme, & Antiretroviral drugs limit progression of HIV retrovirus
Seven Classes of Antiretroviral Drugs are Nucleoside reverse transcriptase inhibitors (NRTIs), Non-nucleoside reverse transcriptase inhibitors (NNRTIs), Nucleotide reverse transcriptase inhibitors (NtRTIs), Protease inhibitors, Fusion inhibitors, Chemokine receptors, & Integrase inhibitors
Nucleoside Reverse Transcriptase Inhibitors (NRTIs) Mimic a DNA building block to inhibit the actions of the enzyme nucleoside reverse transcriptase
Created by: moekah
Popular Pharmacology sets

 

 



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