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pht 101 c5p3
chapter 5 part 3
| Question | Answer |
|---|---|
| voriconazole (VFEND) Can be started IV as and switched to | oral dose |
| voriconazole (VFEND) Can cause | liver toxicity and blurred vision |
| Caspofungin (Cancidas) Inhibits synthesis of | D-glucan, important cell wall component of fungus |
| Caspofungin (Cancidas) is Only available in | IV form for invasive aspergillosis if unresponsive to other therapies |
| fungus | a single celled eukaryotic organism (similar to human cell more than bacteria); but with rigid cell wall, no chlorophyll, & spores to reproduce |
| eukaryotic | nucleus having organism |
| prokaryotic | no nucleus; like bacteria |
| cholesterol | an white, waxy, powdery substance present in all foods of animal not in foods of plant origin; circulates continuously in the blood for use by all cells; a eukaryotic sterol that in higher animals is the precursor of bile acids and steroid hormones |
| bacteria | small, single-celled microorganisms that exist in three main forms: spherical (i.e., cocci), rod shaped (i.e., bacilli), and spiral (i.e., spirilla) |
| aerobic | needs oxygen to survive |
| anaerobic | survives in the absence of oxygen |
| nosocomial infection | infections acquired by patients when they are in the hospital |
| Gram staining | a testing technique in which bacteria are stained to determine if they are gram-positive (purple) or gram-negative (red) |
| ergosterol | a form of lipid found in the cell membrane of fungi |
| permeability | the quality of allowing substances and electrolytes to leak through |
| troche | a small lozenge |
| immunocompromised | having a deficiency in the immune response system |
| A Virus is a | Minute infectious agent, Does not have all components of a cell, Replicate within cell by using metabolic process of host cell, & Can only replicate within a living host cell: animal, plant, or bacteria |
| A virus is much smaller than | a bacterium |
| a virus can infect | a bacterium |
| Most viruses spread by | Direct contact • Ingestion of contaminated food and water, Inhalation of airborne particles, & Exposure to contaminated body fluids/equipment |
| Virion is | An individual virus particle capable of infecting a living cell, Consists of nucleic acid, DNA or RNA, & Capsid (protein shell) surrounds and protects nucleic acid |
| Depending on virus, capsid is | Covered with a membrane called an envelope but Not covered with an envelope |
| Naked virus | a virus without an envelope |
| Five Stages of Viral Infections are | Virus attaches to a cell receptor, Virus penetrates cell as cell membrane indents and closes around the virus, & Virus escapes into the cytoplasm of the cell |
| Virus uncoats | Sheds its covering & Releases DNA or RNA into cell nucleus |
| Virus converts nuclear activity in the cell to | viral activity and reproduces new viral particles |
Created by:
moekah
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