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pht 101 c4p5
chapter 4 part 5
| Question | Answer |
|---|---|
| Monobactam is | aztreonam (Azactam) |
| Tetracyclines are | Broad-spectrum bacteriostatic antibiotics |
| Tetracyclines Inhibit protein synthesis in | bacteria by binding to ribosomes |
| Tetracyclines Suppress infection, but require | phagocytes to eradicate bacteria completely |
| Tetracyclines are | demeclocycline (Declomycin), doxycycline (Vibramycin, Oracea, Adoxa), minocycline (Minocin, Soladyne), & tetracycline (Sumycin) |
| Therapeutic Uses of Tetracyclines are | Acne, Anthrax, Chronic bronchitis, Lyme disease, Mycoplasma pneumoniae infection, Rickettsia infection, & Some sexually transmitted diseases, such as Chlamydia infection |
| Side Effects of Tetracyclines are | Gastrointestinal upset with nausea and vomiting |
| Avoid taking Tetracyclines with | antacids to avoid chelation with minerals |
| Avoid Photosensitization with | Tetracyclines |
| Pregnant women and children up to age 9 must | avoid Tetracyclines |
| Expired drugs can be toxic because, | can cause fatal renal syndrome |
| Pharmacy technician always watch the | expiration date |
| Government agencies stockpiling tetracyclines due to | concern over terrorist attack |
| Due to toxicity, Tetracyclines | must be rotated; destroy when out of date |
| New drug class for Tigecycline is | glycylcycline |
| Tigecycline is Similar to | tetracyclines |
| Tigecycline is Used for | Skin infections & Intra-abdominal infections |
| Tygacil | tigecycline |
| Macrolides Inhibit protein synthesis by | combining with ribosomes |
| Macrolides is Used primarily to treat | pulmonary infections |
| Macrolides are | azithromycin (Zithromax), clarithromycin (Biaxin), dirithromycin (Dynabac), erythromycin base (Ery-Tab), erythromycin ethylsuccinate (E.E.S., EryPed), erythromycin lactobionate (Erythrocin), erythromycin stearate (Erythrocin), & (Pediazole) |
| Pediazole | erythromycin-sulfisoxazole |
| Eryc, Ery-Tab | erythromycin base |
| Therapeutic Uses of Macrolides are | Chlamydia – Group A beta-hemolytic streptococcus, H. influenzae, Legionnaires’ disease, M. pneumoniae, & S. pneumoniae |
| Most Macrolides are taken | on empty stomach |
| Some forms of erythromycin can cause | severe GI distress and should be taken with food |
| Erythromycin & azithromycin Can be | misread |
| Dosing should help | identify drug |