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pht 101 c4p4
chapter 4 part 4
| Question | Answer |
|---|---|
| Penicillinase-resistant penicillins work against | gram-positive aerobes |
| Extended-spectrum penicillins are | more resistant to gram-negative bacteria |
| Penicillin combinations | improve effect |
| The Cephalosporins Mechanism of action are | similar to penicillins |
| Person allergic to penicillin has | about 1% chance of being allergic to cephalosporins |
| The First-Generation Cephalosporins are | cefadroxil (Duricef), cefazolin (Ancef), & cephalexin (Keflex) |
| the Second-Generation Cephalosporins are | cefaclor (Ceclor), cefprozil (Cefzil), & cefuroxime (Ceftin, Zinacef) |
| the Third-Generation Cephalosporins are | cefdinir (Omnicef), cefditoren (Spectracef), cefixime (Suprax), cefotaxime (Claforan), cefpodoxime (Vantin), ceftazidime (Fortaz), ceftibuten (Cedax), ceftizoxime (Cefizox), & ceftriaxone (Rocephin) |
| the Fourth-Generation Cephalosporin is | cefepime (Maxipime) |
| Alert pharmacist if patient who is allergic to penicillin is | receiving a cephalosporin Rx |
| If patient wants cephalosporin dispensed, document | communication in case of cross-reaction |
| First-Generation Cephalosporins are Similar to penicillinase-resistant penicillins but | have greater gram-negative coverage |
| First-Generation Cephalosporins Used for | Community-acquired infections & Mild to moderate infections |
| Second-Generation Cephalosporins Increased | activity, especially against Haemophilus influenzae |
| Second-Generation Cephalosporins are Used for | Otitis media in children, Respiratory infections, & Urinary tract infections (UTIs) |
| Third-Generation Cephalosporins are Active against | wide spectrum of gram-negative organisms |
| Third-Generation Cephalosporins have a | Long half-life, so once-a-day dosing for some |
| Third-Generation Cephalosporins are Used for | Ambulatory patients & Children (dosing before or after school) |
| Fourth-Generation Cephalosporins have a | Broad-spectrum of coverage, such as cefepime (Maxipime) |
| cefepime (Maxipime) which is Used for | Pneumonia, UTIs, & Sepsis |
| cefepime (Maxipime) are in | IV form mixed in NS or D5W |
| Cephalosporins Share side effects of | penicillin |
| A few Cephalosporins Side Effects may initiate | unique toxic reactions |
| Cephalosporins have Lower frequency of | toxicity than many other antibiotics |
| All cephalosporins look alike when | written in the generic form |
| Watch dosing and indications for | use of cephalosporins |
| cephalosporins may need to be | refridgerated |
| New beta-lactam drugs differ | slightly in structure |
| Drugs Related to Penicillins and Cephalosporins are | Carabpenems, carbacephems, and monobactam |
| Some Drugs Related to Penicillins and Cephalosporins are | used for serious infections |
| Carbapenems are | ertapenem (Invanz), imipenem-cilastatin (Primaxin), & meropenem (Merrem I.V.) |
| Carbacephem are | doripenem (Doribax) & loracarbef (Lorabid) |
Created by:
moekah
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