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List at least 4 reasons for compounding?
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Who is compounding regulated by?
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PHM 101
Chapter 9- Compounding
| Question | Answer |
|---|---|
| List at least 4 reasons for compounding? | 1. Pediatric patients requiring diluted adult strengths of drugs 2. Specialized dosages for therapeutic drug monitoring. 3. Compounding for animals 4. Hospice patients for pain |
| Who is compounding regulated by? | The State Boards of Pharmacy and US Pharmacopeia |
| What are some personnel regulations on compounding in a pharmacy? | Pharmacy responsibility to manage. List of qualifications pharmacist must have to compound and recommends further education |
| What are some facilities and equipment regulations on compounding in a pharmacy? | Compounding area must have designated are away from "routine dispensing and counseling functions and high traffic areas" of the pharmacy. Recommended equipment |
| What is the lowest grade of purity for chemicals used in compounding? | USP or NF grade |
| What is quality assurance? | QA- Program of activities used to assure that the procedures used in compounding a product lead to products that comply with specifications and standards |
| What is quality control? | QC- Set of testing procedures that determine the quality of the compounded formulation |
| What are some documentations and record keeping that must be done for compounding? | A formulation record- Recipe. A compounding record- What actually happened when formulation was compounded. Standard operating procedures- SOPs Material safety data sheets- MSDs |
| What is the Beyond-Use Date for nonaqueous liquids and solid formulations? | 25% of the time remaining until the drug product's expiration date or 6 months. Which ever comes first |
| What is the Beyond-Use Date for water containing formulations? | No later than 14 days when stored at cold temp |
| What is the sensitivity of a Class A balance? | Up to 6 mg |
| What is the capacity of a Class A balance? | Minimum weighable quantity of 120 mg of material with a 5% error. Maximum weighable quantity of 60 grams |
| How must the weights be handles with a Class A balance? | With forceps to prevent soiling and erosion of the weights |
| What is the weighing quantities of an electronic balance? | Smaller than 120 mg |
| What is the sensitivity of an electronic balance? | Around 1 mg |
| How often should weighing papers or weighing boats be used? | With each new drug to prevent contamination |
| What is the abbreviation of "to deliver"? | TD |
| What is the abbreviation of "to contain"? | TC |
| What is the best type of graduated cylinder to use? | Cylindrical graduated cylinder because it is more accurate |
| What sizes to syringes usually come in? | From 0.5 ml to 60 ml and in a variety of materials and styles |
| What measuring equipment are not volumetric? | Erlenmeyer flasks. Beakers. Prescription bottles |
| What is important when selecting a liquid measuring device? | Always use smallest device that accommodates volume. Use calibrated pipet, micropipet, or syringe to measure less than 1 ml. Read measurement by meniscus |
| What is important when using graduated cylinders? | Place on flat surface. Hold solution with right hand. As liquid approaches desired amount slow pouring. Transfer liquid to appropriate vessel allowing about 15 s to drain |
| What type of syringe will not take a needle? | Oral syringes because not sterile |
| What are aqueous solutions? | Clear but not always colorless liquids in which the drug is completely dissolved |
| What are syrups? | Concentrated or nearly saturated solution of sucrose in water |
| What are nonaqueous solutions? | Solutions that contain solvents other than water, either alone or in addition to water |
| What is the main solvent for nonaqueous solutions? | Alcohol |
| What are suspentions? | Two phase system consisting of a finely divided solid dispersed in a liquid- usually water |
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Tara3184
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