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CMB-Chapter 12

CMB - Chapter 12 - Basic Anatomy & Physiology

QuestionAnswer
Anatomy is the art of exploring the structure & position of body parts & their relationship to one another
Physiology is the study of the function of those body parts
Homeostasis is the body's ability to maintain relatively stable internal conditions even when subjected to fluctuating environmental conditions
There are ? bones in the body. 206
arthr/o joint
cartilage tissue that protects the ends of the bones by creating a smooth surface facilitating motion
chondr/o cartilage
costa, costal ribs
deposition process by which bone is made by osteoblasts
ligaments connective tissue that connects bone to bone
ossi-, oste/o bone
osteoblast cell responsible for making or forming bone
osteoclast cell responsible for breaking down old bone tissue
osteocyte an osteoblast that has been converted into a bone cell to form bone
remodeling process by which the body recycles old bone
resorption process by which bone is destroyed by osteoclasts
tendon tissue that connects muscles to bone
gout condition created by a buildup of uric acid in joints & tendons that promotes an inflammatory reaction resulting in sudden & excruciating pain
ostealgia any pain in the bones
osteoarthritis load-bearing disorder in which cartilage is worn away resulting in joint inflammation caused by the repeated bone to bone contact
osteoporosis a thinning of the bones making the bones more brittle & more susceptible to fracture
rheumatoid arthritis an autoimmune disorder in which cartilage is destroyed, resulting in joint inflammation, pain, weakness, fatigue, & stiffness
sprain injury to a joint usually caused by the overuse or overstraining of the joint, resulting in stretching of the ligaments
strain injury to a muscle, tendon or ligament resulting in overextension or overstretching
? & ? are used to decrease any further breakdown of bone by osteoclasts. Bisphosphonates & Calcitonin
? is a med that works by stimulating mostly osteoblasts Teriparatide
Our bodies contain ?, ?, & ? muscles. skeletal, smooth & cardiac
autonomic nervous system (ANS) system that controls involuntary muscles
cardiac muscle type of muscle tissue found in the heart that is controlled involuntarily & functions by constantly pumping oxygenated blood to tissues & organs
involuntary automatic
my/o muscle
sarc/o flesh, muscle
skeletal muscle muscle under voluntary control, biceps
smooth muscle muscle controlled involuntarily, digestive tract muscles
somatic nervous system (SoNS) nervous system that controls voluntary muscles
spasm involuntary muscle contraction
tendon connects muscle to bone
myalgia muscle pain or tenderness
myasthenia gravis condition characterized by chronic fatigue & muscle weakness
myosclerosis abnormal hardening of muscle tissue
rhabdomyolysis adverse effect of muscle weakening caused by several medications used to treat high cholesterol
? is commonly used in surgery to prevent muscle contractions during operations. Succinylcholine
? & ? are toxic substances that cause muscle weakening & paralysis. Curare & botulin
meds like ? stimulate skeletal muscle cells edrophonium
? is a smooth muscle antagonist which may cause constipation, used in IBS. Dicyclomine
? is a smooth muscle agonist which may cause diarrhea, used for urinary retention. Bethanechol
? is a beta-blocker which relaxes the heart muscle, used in hypertension, which relaxes the heart muscle. Metoprolol
? is a beta-agonist which works by stimulating the heart to pump oxygenated blood to body organs & tissues, is used in end stage heart failure & shock. Dobutamine
BP is determined by the contraction & relaxation of the ventricles
ventricles contract = systolic phase/pressure
ventricles relax = diastolic phase/pressure
angioplasty surgical repair of a blood vessel
artery blood vessels that transport oxygenated blood away from the heart to body cells & tissues
capillaries very small blood vessels where oxygen from RBCs are exchanged for carbon dioxide
cardi/o heart
cardiology study of the structures, functions, & disorders of the heart
cholesterol type of lipid that circulates in the blood & can form plaque that can block blood vessels
erythrocyte rbc that transports oxygen to body tissues & organs
hem/o, hemat/o blood
hemoglobin an iron containing protein found in RBCs that carries oxygen from the lungs to body organs & tissues, & carries carbon dioxide from the body organs & tissues to the lungs for exhalation
high-density lipoprotein (HDL) good cholesterol
low-density lipoprotein (LDL) bad cholesterol
myocardial muscle of the heart
anemia a reduction in the # of RBCs & hemoglobin
angina chest pain but not as severe as a heart attack
arrhythmia irregular heartbeat
arteriosclerosis condition in which artery walls become thick & stiff
bradycardia decreased heart rate
congestive heart failure (CHF) condition in which the heart fails to pump blood efficiently
edema also known as hypervolemia, in which an excessive amount of fluid accumulates in the body
endocarditis inflammation of the heart muscle; usually caused by bacteria
hemorrhage bleeding due to trauma or a wound
hypertension chronic high blood pressure; diagnosed as greater than 140/90
ischemic heart disease (IHD) obstruction of the blood supplied to the heart due to a buildup of lipids or fat in the arteries
leukemia cancer in the bone marrow which prevents the formation of functional white & red blood cells
myocardial infarction damage to the heart muscle; heart attack
stroke serious neurological condition, caused by a decrease of oxygen supplied to the brain that can result in weakness, loss of control over muscles, difficulty speaking, &/or death
tachycardia a rapid heart rate
typical drug classes used to treat hypertension ACE-I, alpha blockers, beta blockers, calcium channel blockers, & diuretics
anticoagulation preventing clotting of the blood
antithrombin a naturally occurring protein stimulated by certain medications to counteract the effects of thrombin resulting in anticoagulant
coagulation clotting of the blood
fibrin protein formed from the conversion of fibrinogen which acts by forming a net to stabilize the platelet plug, thus forming a thrombus or clot
fibrinogen substance converted to fibrin by the direct stimulation of thrombin
plasmin enzyme responsible for breaking down fibrin, resulting in anticoagulation
plasminogen substance converted to plasmin by the direct stimulation of the thrombolytic drug class
platelet small blood cell responsible for forming a platelet plug during blood coagulation
platelet activation 2nd step in the formation of a platelet plug in which a platelet changes its shape to better form the platelet plug while exposing IIb/IIIa receptors
platelet adhesion 1st step in the formation of a platelet plug in which a platelet sticks to a damaged area on an artery
platelet aggregation 3rd step in the formation of a platelet plug in which platelets stick to each other by binding to IIb/IIIa receptors thus forming a stable platelet plug
prothrombin substance converted to thrombin by the stimulation of the cofactor complex of factors Va and Xa
thrombin (factor IIa) a major protein responsible for blood coagulation that works in the clotting cascade & also stimulates platelet activation
thrombocyte also known as a platelet
thrombus a blood clot
Von Willebrand factor (vWf) substance exposed on a damaged artery surface that allows platelets to stick to & begin the formation of a platelet plug
deep vein thromboembolism (DVT) condition characterized by abnormal clotting usually in leg arteries in which the leg may appear red, swollen, & painful
embolism an object, such as a blood clot, which dislodges & travels through the bloodstream until it blocks a smaller blood vessel, thereby cutting off blood flow
peripheral artery disease (PAD) condition characterized by a decreased blood supply to arms &/or legs
pulmonary embolism (PE) condition characterized by the dislodging of a portion of blood clot, which travels to the lungs & causes difficulty breathing
thrombus a blood clot that blocks blood flow
venous thromboembolism (VTE) a general term that encompasses deep vein thromboembolism (DVTs) & pulmonary embolism (PE)
Apnea An absence of spontaneous respiration
Asphyxia Abnormal or pathologic changes caused by an absence of oxygen
Aspiration The act of inhaling a foreign substance into the lungs often after vomiting
Dyspnea Shortness of breath
Expiration the act of breathing out as the diaphragm relaxes
Histamine (H1) a chemical released by mast cells during an allergen reaction which may cause symptoms such as sneezing, runny nose, wheezing, and watery eyes
Hyperventilation a condition characterized by rapid breathing, resulting in decreased carbon dioxide levels and increased oxygen levels, producing faintness, tingling of the fingers and toes, and possibly loss of consciousness
Inhalation The act of breathing in as the diaphragm contracts
Respiratory rate also known as breaths per minute, which is an important numeric value used for diagnosing respiratory conditions
Rhinorrhea An excessive flow of mucus from the nose (runny nose)
Allergic rhinitis nasal inflammation characterized by an increased flow of mucus; caused by allergies
Asthma breathing disorder, often triggered by allergies or exercise, resulting in constriction of the bronchi. Asthma is often accompanied by tightness in the chest, coughing, wheezing and difficulty in breathing.
Chronic bronchitis Inflammation of the bronchi usually caused by an infection in which the patient has a productive cough and may have difficulty getting sufficient oxygen. Some patients with bronchitis may have a bluish tint to lips or skin
Chronic Obstructive Pulmonary Disease (COPD) condition characterized by emphysema and chronic bronchitis, usually caused by smoking, resulting in difficulty breathing and increased risk of infection.
Cystic fibrosis Genetic disorder affecting mostly Caucasian populations, where excessive amounts of thick mucus blocks the airways, resulting in wheezing, coughing, and increased susceptibility to bacterial infections.
Emphysema A condition characterized by shortness of breath, usually caused by smoking. Some patients may have a pinkish tint to the face and may often gasps for air
Influenza (flu) An acute, highly contagious viral respiratory infection, which is spread by coughing, sneezing and sharing items such as food utensils
Laryngitis Inflammation of the larynx (voice box), resulting in temporary inability to speak normally
Lung Cancer Disorder in which non-functional cells (or tumors) are produced in the lungs. Lung cancer is usually caused by smoking
Pertussis A contagious bacterial infection, resulting in a loud, deep coughing; also known as whooping cough
Pharyngitis Inflammation of the pharynx (or throat)
Pneumonia Disease of the lungs characterized by inflammation of the lungs and congestion; often caused by bacteria or viruses
Sinusitis Infection and inflammation of the membranes lining the sinuses
Tonsillitis Infection and inflammation of the tonsils
Inhaled corticosteroids (ICS) used for respiratory conditions
oral corticosteroids used for respiratory conditions
short acting beta agonists (SABA) used for respiratory conditions
long acting beta agonists (LABA) used for respiratory conditions
short acting anticholinergics (SA AC) used for respiratory conditions
long acting anticholinergics (LA AC) used for respiratory conditions
Allergen Any substance capable of causing an allergic response
Allergy An altered reaction of body tissues in response to an allergen that affects some people who are sensitive to that allergen, but not others
Antigen A substance such as a bacterium or a virus, which the body recognizes as foreign
Antibody A protein produced by the immune system that targets a specific antigen to inhibit it from invading the body cells and tissues
Antibiotic A medication that is used to stop the growth of bacteria but is not effective in viral infections
Antiviral A medication used to treat viral infections or provide temporary immunity
Antihistamine A medication that blocks histamine, a type of allergen that is produced by white blood cells, to control allergic reactions
Bacteria Name given to a group of single-celled microorganisms. Some bacteria can be helpful while others can be harmful to the body
Immunosuppressant A medication that prevents or reduces the immune system's defensive actions that usually protect the body from invasion by foreign substances, such as bacteria and viruses; a type of medication often used by patients who have had organ transplants or cert
Infection Invasion of the body by a bacterium or virus
Inflammation A localized response to injured tissue, usually causing heat, pain, redness, and swelling
Leukocyte A white blood cell which functions by fighting infections
Pathogen A microorganism (bacteria or virus) that can cause a disease
Virus A microorganism that invades body cells and replicates itself to eventually invade or spread to neighboring tissues
Cellulitis Bacterial infection common on the legs, usually caused by strep or staph infections
Chickenpox A highly contagious acute viral disease characterized by fever and pustules on the skin
Hepatitis A and E Inflammation of the liver caused by viruses, usually acquired by consuming contaminated food or water
Hepatitis B and C Inflammation of the liver caused by viruses usually acquired by unprotected sex, IV drug abuse, or passed from the mother to child during pregnancy
Human immunodeficiency virus (HIV) A virus that targets specific white blood cells (CD4 white blood cells) resulting in compromised immunity. Untreated HiV infections may lead to acquired immunodeficiency syndrome (AIDS)
Lymphoma Cancer in the lymph nodes which results in decreased immunity and increased susceptibility to infection
Lupus An autoimmune disorder usually characterized by a decrease in blood cells, arthritis, and skin abnormalities, especially on the face (butterfly rash)
Measles Highly contagious viral disease characterized by fever and small red spots with blue-white centers that appear on the skin and inside the mouth
Mumps Anacute viral disease characterized by swelling of the salivary glands
Ringworm A type of fungal infection characterized by a raised red ring on the skin
Shingles A painful inflammation of nerve cells, usually on the trunk of the body, caused by the same virus that causes chicken pox, which may occur many years or decades after exposure to the virus
Medications that kill bacteria are referred to as bactericidal
Medications that inhibit the growth of bacteria are referred to as bacteriostatic
Medications that inhibit cell wall formation are referred to as bactericidal
Medications that work on protein synthesis are referred to as bacteriostatic
Absorption Movement of a drug, nutrient, or water from the intestines into the circulatory system (or bloodstream)
ADME Acronym that describes how the drug moves into and out of the body. "A" = absorption, "D" = distribution, "M" = metabolism, and "E" = excretion
Antiemetic A medication used for motion sickness that prevents or relieves nausea and vomiting
Bile A fluid secreted by the liver that aids in the digestion of fats
Carbohydrate One of three major nutrients obtained from the diet and used for energy. Carbohydrates are found in bread, milk, fruits and vegetables. Simple sugars are the building block for carbohydrates. TPNs often contain carbohydrates in the form of dextrose.
Chief cells Cells located in the digestive tract that secrete pepsinogen which is then converted to pepsin to aid in the digestion of proteins
Colon The large intestine
Colonoscopy direct visual examination of the inner surface of the colon.
Cyclooxygenase (COX) Enzyme responsible for the formation of prostaglandins and the site that is inhibited by several pain medications including NSAIDs.
Digestion The breakdown and dissolving of food into smaller particles.
Distribution The process of carrying the drug through the body to its site of action.
Enter/o Intestine
Enterochromaffin-like (ECL) cell Cell located in the digestive tract which release histamine to stimulate parietal cells thus increasing the amount of stomach acid produced.
Excretion The process of expelling waste from the body by urination or defecation.
Fat One of three major nutrients obtained from the diet and used for energy. Fats are found in meats, butter, oils, etc. Fatty acids are the building block of fats. TPNs often contain fats in the form of a milky white Intralipid fat emulsion.
G cells Cells located in the digestive tract which secrete gastrin which stimulates ECL cells and parietal cells thus increasing the amount of stomach acid produced.
Gastrin Hormone responsible for stimulating parietal and ECL cells to increase the amount of stomach acid produced.
Gastr/o Stomach
Goblet cells Cells located in the digestive tract responsible for secreting mucus to protect the lining of the digestive tract from stomach acid
Hepat/o Liver
Histamine Substance secreted by ECL cells which stimulates H2 receptors on parietal cells resulting in an increase in stomach acid secretion.
Laxative A medication used to stimulate elimination of waste products from the colon, or large intestine.
Metabolism A set of chemical reactions that occur within organisms in order to create energy and maintain tissues. Breaking down large molecules releases energy that is then used to build cells and proteins. The processes included in metabolism are also responsible
Mucous Term that refers to membranes that secrete mucus.
Mucus Substance secreted by mucous membranes and goblet cells that functions to protect the digestive tract from stomach acid.
Or/o Mouth
Parietal cells Cells located in the digestive tract responsible for directly secreting stomach acid. H2As and PPIs work on these cells to treat GERD and heartburn.
Pepsin Enzyme formed from pepsinogen which aids in the digestion of proteins.
Pepsinogen Substance secreted by chief cells which converts into pepsin in the presence of stomach acid.
Peristalsis Contractions of the smooth muscle in the GI tract that propel or move food down the GI tract.
Prostaglandin Substance secreted by COX which protects the digestive tract lining by stimulating mucus production
Protein One of three major nutrients obtained from the diet. Proteins are found in meats, eggs, beans, milk, etc. Amino acids are the building block of proteins. TPNs often contain protein in the form of Aminosyn.
Proton pump A pump located in parietal cells which secretes stomach acid when parietal cells are stimulated
Sublingual Under the tongue.
Total parenteral nutrition (TPN) A large volume IV bag given to patients who cannot consume food (NPO) or nutritional formula (like Ensure) for a prolonged period of time. TPNs contain major nutrients (carbohydrates, proteins, fats), along with electrolytes and vitamins
the three major nutrients are carbohydrates, proteins, & fats
Cirrhosis A hardening of the liver caused by alcohol abuse and hepatitis.
Colon cancer Tumor growth in the colon. Patients should be screened for colon cancer by having a colonoscopy every 10 years starting at age 50 (unless at high risk.)
Constipation A condition in which the colon has difficulty eliminating waste products.
Diarrhea Abnormal frequency of loose or watery discharge from the colon that can result in dehydration
Gastroesophageal reflux disorder (GERD) Disease in which the contents of the stomach are pushed or refluxed back into the esophagus. GERD is commonly characterized by heartburn
Hepatitis Inflammation of the liver caused by viruses, bacterial infections, continuous exposure to alcohol or drugs, or an autoimmune disorders, often resulting in compromised or decreased immunity and decreased overall liver function.
Hyperglycemia An abnormally high concentration of sugar in the blood.
Hypoglycemia A condition characterized by abnormally low levels of sugar in the blood resulting in weakness, fatigue and irritability and possibly hypoglycemic coma.
Hyperlipidemia Excessive amount of fats in the blood; also known as high cholesterol, which can clog blood vessels, especially those of the heart
Irritable bowel syndrome (IBS) A chronic condition characterized by muscle spasms in the intestines and abdominal pain that may be accompanied by constipation or diarrhea.
Liver disease Hardening of the liver often caused by excessive alcohol consumption
Ulcers Open sores or lesions in the GI tract usually in the stomach or intestines that result in pain, inflammation, and/or bleeding
Chief cells secrete Pepsinogen
Cyclooxygenases (COX) secrete Prostaglandin
Enterochromaffin-like (ECL) cells secrete Histamine
G cells secrete Gastrin
Goblet cells secrete Mucus
Parietal cells secrete Stomach acid
Adrenal gland Gland just above the kidney that releases hormones such as epinephrine (adrenaline), norepinephrine, aldosterone, etc.
Aldosterone Hormone secreted by the adrenal gland that works primarily in the distal convoluted tubule (DCT) of the kidney to increase sodium and water reabsorption thus increasing blood pressure.
Angiotensin I Substance released from the liver which is converted to angiotensin II by ACE.
Angiotensin II Potent vasoconstrictor formed from angiotensin that works by directly constricting arteries and activating aldosterone.
Angiotensin converting enzyme (ACE) Enzyme produced in the lungs which converts angiotensin I to angiotensin II.
Antidiuretic hormone (ADH) Hormone released by the posterior pituitary that works in the collecting ducts of the kidney to reabsorb water.
Glomerulus a collection of capillaries located at the beginning of the nephron responsible for filtration of waste from the blood to form urine.
Nephron The functional unit of the kidney consisting of the glomerulus, convoluted tubules, loop of Henle, and collecting ducts. Several medications work in the nephron to lower blood pressure.
Ren/o, ren/i Kidney
Renal Pertaining to the kidneys.
Renin Enzyme released in response to a decrease in blood pressure that stimulates the liver to produce angiotensin I.
Uresis, -uresis Urination; excretion in the urine.
Urinalysis The examination of the urine to determine the presence of certain substances, such as sugar, blood, etc.
Benign prostate hyperplasia (BPH) Enlarged prostate gland characterized by difficulty urinating in males.
Chronic renal failure A condition where the kidney is unable to clear or filter the blood properly.
Cystitis Inflammation of the urinary bladder caused by infection; resulting in the increased urge to urinate and burning sensation upon urinating.
Kidney stones Crystals that develop in the kidneys, ureters, or urethra composed of calcium, uric acid, or other compounds; causes difficulty urinating, blood in the urine, and extreme pain.
Prostate cancer tumor growth in the prostate gland, usually characterized by difficulty urinating.
Renal disease Disease pertaining to the kidneys usually seen in patients with diabetes and high blood pressure resulting in several complications. Renal disease also effects the blood levels of certain medications in the body.
Urethritis Inflammation of the urethra which causes a burning sensation during urination.
Urinary tract infection (UTI) Infection of any part of the urinary tract, usually the urethra and urinary bladder; caused by bacteria.
The ? is a system that acts primarily on the kidney and is where many hypertension medications work. renin-angiotensin-aldosterone system (RAAS)
renin-angiotensin-aldosterone system RAAS
Anesthetic A medication which decreases the body's sensitivity to pain or touch
Anticonvulsant A medication designed to prevent seizures or convulsions
Antidepressant A medication designed to prevent or relieve depression
Antipsychotic A medication used to treat severe psychiatric disorders
Barbiturate A medication class which depresses the CNS, resulting in calmness or sleep
Cephal/o Head
Cerebrospinal fluid (CSF) A clear, watery fluid produced by the brain that helps cushion the brain and the spinal cord from injury
Cyclooxygenase (COX) Enzyme responsible for the formation of prostaglandins and the site that is inhibited by several pain medications including NSAIDs
Dopamine (DA) A hormonal neurotransmitter released by the brain involved in various functions such as attention, memory/learning, emotional arousal, and rewarding sensations
Electroencephalography (EEG) The process of graphing the electrical activity of the brain
Encephal/o Brain
Neuropathy Any disease of the nervous system
Nerv/o, Nerv/i, Neur/o, Neur/i Nerve
Nerve A fibrous group of neurons that connect the brain or spinal cord to other parts of the body
Neuron A specialized impulse-conducting cell that is the functional unit of the nervous system which forms nerves
Norepinephrine (NE) A hormonal neurotransmitter released by neurons in the brain and the periphery that is involved in various functions such as heartbeat, arousal, learning, memory, and appetite
Sedative A medication which depresses the CNS, resulting in calmness or sleep
Serotonin (5-HT) A hormonal neurotransmitter released by the brain involved in various functions such as mood, pain perception, sleep, appetite, and maintaining normal body temperature and hormonal state
Stimulus Anything that excites or activates a nerve
Alzheimer's disease A group of disorders associated with brain degeneration, leading to progressive memory loss and personality changes
Attention deficit hyperactive disorder (ADHD) A behavior disorder, usually in young children, characterized by inattentiveness, hyperactivity, and impulsiveness
Bipolar disorder A condition characterized by irregular, alternating periods of mania and depression
Coma A prolonged state of unconsciousness with no response to stimuli
Dementia Slow, progressive deterioration of the brain affecting everyday activities such as memory, thinking, alertness, and reasoning
Depression A mood disorder characterized by a lack of cheerfulness, dejection, loss of hope, and lack of interest in daily activities
Insomnia A condition characterized by the inability to sleep; usually caused by depression, pain, or excessive caffeine intake
Mania A mental state characterized by excessive excitement and feelings of grandeur
Meningitis Inflammation of the membranes covering the central nervous system (is., brain and spinal cord), characterized by neck stiffness, headache, altered mental status, and fever, usually caused by bacteria
Multiple sclerosis (MS) Chronic, progressive degeneration of the central nervous system that can result in decreased stimulation, paralysis, shakiness, and speech abnormalities
Narcolepsy Syndrome characterized by uncontrolled drowsiness and sleepiness
Obsessive-compulsive disorder (OCD) A condition characterized by persistent ideas, thoughts, or images causing anxiety and distress along with corresponding behaviors designed to reduce anxiety or stress, such as repeated hand-washing
Parkinson's disease A progressive, degenerative central nervous system disorder characterized by constant muscle spasms and shakiness
Posttraumatic stress disorder (PTSD) A condition characterized by anxiety, depression, difficulty concentrating, restlessness, and sleep disorders, caused by a previous traumatic event such as experiencing or witnessing violence
Schizophrenia A psychotic disorder characterized by separation from reality, usually accompanied by abnormal behavior, illogical thinking, and hallucinations
Neurotransmitters (NT) responsible for stimulating the brain serotonin (5-HT), norepinephrine (NE), and dopamine (DA)
Monoamine oxidase MAO
Monoamine oxidase inhibitors MAO-Is
? is found in the synapse and is responsible for inactivating monoamines such as dopamine, norepinephrine, and serotonin Monoamine oxidase
The skin consists of the epidermis, dermis, and hypodermis
The ? is the upper surface where tightly connected, protein-filled cells are produced, giving the skin its continuity and suppleness. epidermis
The ? houses sensory receptors, blood vessels, oil and sweat glands, and hair follicles. dermis
The ? is the area below the dermis consisting of fatty tissue where several medications such as insulin are injected hypodermis, or subcutaneous layer
Derm/a, Derm/o, Dermat/o, -derma skin
Diaphoresis Excessive sweating
Perspiration Sweating
Subcutaneous The layer below the cutaneous (dermal) skin layer and a common location for injections
Topical A route of administration for medication (usually a cream or ointment) which is applied to a localized area on a body surface.
Transdermal A route of administration for medication which is applied to and absorbed through the skin so that it will be absorbed, such as a nitroglycerin or nicotine patch.
Burn Tissue damage resulting from excessive exposure of the skin to heat, chemicals, or radiation. Bums can be classified according to the extent of tissue damage
1st degree burn A superficial bum limited to the outer layer of the epidermis. Lighter- skinned individuals will show redness as with a sunburn.
2nd degree burn A burn that penetrates the epidermis and into the dermis, but not so severely that it inhibits regeneration of the epidermis. Second-degree burns are characterized by blisters
3rd degree burn A burn in which all of the epidermis and dermis are destroyed.
Contusion An injury in which tissues or blood vessels are damaged but does not break the skin; a bruise
Contact dermatitis Inflammation of the skin characterized by redness and itching; caused by contact with an irritant or allergen
Eczema (atopic dermatitis) An acute or chronic skin inflammation characterized by redness, scales, scabs, and itching.
Gangrene Tissue death followed by bacterial infection, resulting in foul-smelling decayed sores.
Hives A condition in which the skin reacts to allergens or stress by developing round elevations with red edges and pale centers
Impetigo A contagious bacterial infection common in children and results in red lesions, usually around the face and hands
Laceration A cut or tear in the skin
Melanoma A form of skin cancer that may result from excessive exposure to the sun
Pruritus Itching
Psoriasis Metabolic skin disorder in which the skin has red raised rashes with white to silver scales caused by accelerated growth of skin cells.
Ringworm A type of fungal infection characterized by a raised red ring on the skin
Septic shock Severe complication of an infection resulting in organ dysfunction and abnormally low blood pressure; often resulting in severe shock or sudden death.
Tinea pedis (athlete's foot) Highly contagious fungal infection on feet and between toes; characterized by dry and crusty areas of skin
Wart An elevated growth on the skin usually caused by a virus
The ? , located in the brain, secretes melatonin, which increases concentration in the blood at night and makes people drowsy and decreases during daylight hours pineal gland
The ? is also located in the brain and secretes a number of hormones which regulate various bodily functions including growth, reproduction, and some metabolic functions pituitary gland
The butterfly-shaped ? is located in the neck and releases thyroid hormone, which is the body's major metabolic hormone. Thyroid hormone affects body temperature, appetite, weight, and blood pressure among other things. thyroid gland
The ? are located on the thyroid gland and secrete parathyroid hormone, regulating the calcium balance in the blood. four parathyroid glands
The ?, located in the chest, promotes the maturity of lymphocytes, thus playing an important role in immune system function. thymus
The ?, located in the abdomen, releases glucagon and insulin to raise and lower blood sugar, respectively. pancreas
The ? are located on top of the kidneys. They secrete aldosterone, cortisol (hydrocortisone), testosterone, epinephrine, and norepinephrine adrenal glands
? regulates sodium and water levels Aldosterone
? helps the body resist stressors cortisol
? contributes to the onset of puberty and the development of pubic hair Testosterone
? promote the "fight or flight" effects in response to emergency situations epinephrine and norepinephrine
Effector organ The organ affected by the respective hormone
Glucose A simple sugar obtained from the diet that is stored by insulin to be used for energy in the future
Hydrocortisone A synthetic hormone used to relieve or reduce inflammation, pain, and organ rejection
Hypothalamus A part of the brain that controls various functions such as maintaining body temperature, regulating sleep, and releasing hormones that stimulate the pituitary gland. The hypothalamus secretes "releasing" hormones which have effects on pituitary gland.
Insulin Hormone secreted by the pancreas in response to high blood glucose levels that aids in the storage of blood glucose (in the form of glycogen and fat) to be used for energy in the future.
Goiter The abnormal development of the thyroid gland resulting in an enlargement in the frontal part of the neck
Hyperparathyroidism A condition characterized by abnormally high levels of parathyroid hormone in the body resulting in weak bones
Hypoparathyroidism A condition characterized by abnormally low levels of parathyroid hormone in the body, resulting in cramps among other things.
Hyperthyroidism A condition characterized by excessive thyroid hormone levels in the body, resulting in increased sweating, nervousness, and weight loss
Hypothyroidism A condition characterized by deficient amounts of thyroid hormone levels, resulting in fatigue, depression, and weight gain
Hormones released from the hypothalamus are called ? and are abbreviated as ? "releasing hormones" / RH
The pituitary gland releases ? and are abbreviated ? "stimulating hormones" / SH
thyroid releasing hormone TRH
thyroid stimulating hormone TSH
Chlamydia A highly contagious STI caused by a bacterium that results in damage to the reproductive organs if not treated early.
Genital herpes An STI caused by a virus characterized by painful blisters on the genitals. Genital herpes cannot be cured but symptoms may be treated.
Gonorrhea An STI caused by a bacterium characterized by a burning or painful sensation while urinating, vaginal or penile discharge, and sore throat.
Syphilis An STI caused by a bacterium; characterized by painless sores, swollen lymph nodes, fever, fatigue, and loss of appetite. Syphilis can be cured with prompt treatment and follow-up.
Trichomoniasis An STI caused by a protozoan; characterized by pain during sexual intercourse, vaginal or penile discharge, and itching. Trichomoniasis can be cured with appropriate therapy.
Osteoblast require ? & ? to form new bone Ca & phosphate
Created by: cbowers101
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