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dleary Ch.3
para vs sympathetic
| Question | Answer |
|---|---|
| Heart | Parasympathetic Effect-decreases rate and contractile force Sympathetic effect- increases rate and contractile force. |
| Lungs | Parasympathetic effect- Bronchoconstricts Sympathetic effect- Bronchodilates |
| Eyes | Parasympathetic effects-Pupil constriction Sympathetic effects-Pupil dilation |
| Hair muscles | Parasympathetic effects-Relaxes Sympathetic effects -contracts and causes hair to stand on end (piloerection) |
| Gastrointestinal | Parasympathetic effect- increases digestion sympathetic effect- decreases digestion |
| urinary | Parasympathetic effect- Constricts bladder sympathetic effect- relaxes bladder |
| Adgernergic receptors | |
| Alpha 1 | Tissue-Vascular smooth muscle,pupil,pilomotor smooth muscle. Action- contracts, dilation (mydriasis), goose bumps. |
| Beta 1 | Tissue- heart Action- stimulates rate and force |
| Beta 2 | Tissue- Respiratory, somatic motor ( voluntary muscle) Action- Bronchodilates, tremors |
| Dopamine | Tissue- Renal Action- Relaxes arteries |
| Cholinergic agonist and indications | |
| Direct acting- stimulates cholinergic receptors Bethanechol | indication- urinary retention |
| Direct acting-stimulates cholinergic receptors Succinylcholine | indications- neuromuscular blockade- intubation |
| Direct acting-stimulates cholinergic receptors Pilocarpine | indications-Glaucoma |
| indirect-acting-decreases AChE activity Neostigmine | Myasthenia gravis |
| indirect-acting decreases AChE activity- Pyridostigmine | Reversal of neuromuscular blockade |
| indirect-acting decreases AChE activity- Malathion | Insecticide |
| indirect-acting decreases AChE activity-nerve gas | Chemical Warfare |
| Anticholinergic drug class | |
| catagory and function- antimuscarinics- increases heart rate and bronchodilation | drug- Atropiine ipratropium brormide (atrovent) |
| Nicotinic blockers-at preganglionic sites- prevent nervous transmission | drug- hexamethonium |
| Sympathomimetic drugs | |
| Catecholamines- Epinephrine | indications- anaphylaxis |
| catecholamines- norepinephrine | indications - hypotension |
| catecholamines- dopamine | indications- shock |
| catecholamines- dobutamine | indications- shock, heart failure |
| phenylephrine | indications- nasal decongestant. hypotension |
| albuterol | indications- asthma |
| sympatholytic drug sub group | |
| alpha-blocker- drug- Doxazosin | indications- hypertension, benign prostate hypertrophy |
| Beta-blocker- drug- propranolol | indication- hypertension |
| Cholinergic/Parasympathomimetic | drugs that stimulate or mimic the parasympathetic receptors |
| Anticholinergic/ Parasympatholytics | drugs that block parasympathetic receptors |
| Adrenergic/sympathomimetics | drugs that stimulate or mimic the sympathetic receptors |
| Antiadrenergic/sympatholytics | drugs that would antagonize the sympathetic response. |