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Stack #78319
Fred Top 10 Final Exam
| Generic/Trade | Classification | Indications | Action |
|---|---|---|---|
| famotidine/Pepsid | ANTI-ULCER, HISTAMINE H2 ANTAGONISTS | • Short-term treatment of active duodenal ulcers and benign gastric ulcers • Prophylaxis of duodenal ulcers (at lower doses)• Management of GERD .Management of gastric hypersecretory states (Zollinger-Ellison syndrome) | Inhibits the action of histamine at the H2-receptor site located primarily in gastric parietal cells, resulting in inhibition of gastric acid secretion |
| heparin | ANTICOAGULANT | Prophylaxis and treatment of various thromboembolic disorders | Potentiates the inhibitory effect of antithrombin on factor Xa and thrombin |
| clopidogrel/Plavix | Thera: antiplatelet agents Pharm: platelet aggregation inhibitors | • Reduction of atherosclerotic events (MI, stroke, vascular death) in patients at risk for such events including recent MI, acute coronary syndrome (unstable angina/non-Q-wave MI), stroke, or peripheral vascular disease. | • Inhibits platelet aggregation by irreversibly inhibiting the binding of ATP to platelet receptors • Therapeutic Effects: Decreased occurren.ce of atherosclerotic events in patients at risk. |
| furosemide/LASIX | DIURETIC (loop) | • Edema due to: CHF or Hepatic or renal disease • Hypertension | • Inhibits the reabsorption of Na & Cl from the loop of Henle and distal renal tubule • Increases excretion of H20, Na,Cl,Mg, H+,& Ca =Diuresis and lower blood pressure |
| zolpidem/Ambien | SEDATIVE/HYPNOTIC | insomonia | • Produces CNS depression by binding to GABA receptors • Has no analgesic properties Therap Effects: Sedation & induction of sleep |
| alprazolam/Xanax | Therapeutic: antianxiety agents Pharmacologic: benzodiazepines | • Treatment of anxiety • Management of panic attacks • Unlabelled Uses:• Management of symptoms of premenstrual syndrome (PMS) | • Acts at many levels in the CNS to produce anxiolytic effect • May produce CNS depression • Effects may be mediated by GABA, an inhibitory neurotransmitter • Therapeutic Effects: Relief of anxiety |
| promethazine/Phenergan | Thera: antiemetics,antihistamines, sed/hyp Pharmacologic: phenothiazines | • Tx of various allergic conditions & motion sickness • Preoperative sedation • Treatment & prevention of N/V • Adjunct to anesthesia & analgesia | • Blocks the effects of histamine • Has inhibitory effect on the CTZ in the medulla, resulting in antiemetic properties • Alters the effects of dopamine in the CNS |
| phenytoin,fosphenytoin/Dilantin | Thera: antiarrhythmics (class IB), anticonvulsants Pharm: hydantoins | (blank) | (blank) |
| levodopa/Dopar, Larodopa, L-dopa | ANTIPARKINSON AGENTS, DOPAMINE AGONISTS | Parkinson's Disease | Levodopa is converted to dopamine in the CNS, where it serves as a neurotransmitter. • Thera Effects: Relief of tremor & rigidity |
| glyburide | ANTIDIABETICS, SULFONYLUREAS | PO: Control of blood sugar in type 2 diabetes mellitus when diet therapy fails. Requires some pancreatic function | • Lowers blood sugar by stimulating the release of insulin from the pancreas and increasing the sensitivity to insulin at receptor sites • May also decrease hepatic glucose production |