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Therapy Jeopardy
Anti-Infectives
| Question | Answer |
|---|---|
| PEN DOC for Listeriosis | Ampicillin |
| DOC for syphilis | Penicillin |
| Subclass of PEN with most activity vs MSSA | anti-staphycoccals? |
| Drug which can be used in gout reduced in increased pen levels | probenecid |
| Considered the anti- pseudomonal PENs | Extended spectrum (tigracillin) |
| Common IV Cephalosporin most like antistaphyloccal PEN | first generation (cephazolin) |
| Ceph which does not require renal adjustment | Rocephin |
| Ceph contraindicated in neonates receiving calcium containing solutions | rocephin, another one too? |
| 3rd generation ceph with poor activity vs MSSA | ceftazodine? |
| Ceph with activity vs MRSA | 5th gen cefteraline? (only beta lactam vs MRSA) |
| Quinolone with greatest activity vs pseudomonias (P aeruginosa) | Cipro |
| Effect of quinolones on blood glucose | both increase and decrease |
| Quinolone which should not be used in treatment of UTI | Moxifloxacin |
| Likelihood of resistance in Staph aureus to Cipro | increase |
| Which quinolone has been associated with C diff infection | all of them (class effect) |
| This protein syn inhibitor is most associated with diarrhea | Erythromycin |
| This macrolide is not metabolized thru the 3A4 system | Azithromycin |
| This protein syn inhibitor only has activity vs Gram + organisms | Zosyn |
| This protein syn inhibitor could result in thrombocytopenia | Zosyn |
| These 2 classes of protein syn inhibitors can cause hearing loss | Macrolides (less), Aminoglycosides (more) |
| The effect of Aztreonam of Group A strep | no effect (gram – only drug) |
| The effect of Vancomycin on E Coli | no effect |
| Likelihood you will experience hangover effect if flagyl is taken with alcohol | increase |
| Likelihood of drug interaction between mag ox and minocycline | increase |
| Likelihood of anaphylactic reaction with Aztrenoam in Pen allergic patient | decrease |
| A concentration dependent killer with excellent activity vs MRSA | Daptomycin |
| A concentration dependent killer with activity vs anaerobes | flagyl |
| This fluroquinolone is partially metabolized thru the CYP system | Cipro (1A2) |
| Combination of Pen and this class is thought to result in synergistic activity | aminoglycosides |
| This drug class interferes with metabolism of valproic acid | Carbepenims |
Created by:
amj7997
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