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Drugs and Drug categ
PHAR 341
| Question | Answer |
|---|---|
| Tetradotoxin | Natural Toxin - LA |
| Saxitoxin | Natural Toxin - LA |
| Procaine | Ester LA |
| Tetracaine | Ester LA |
| Benzocaine | Ester LA |
| Cocaine | Ester LA |
| Lidocaine | Amide LA |
| Mepivacaine | Amide LA |
| Bupivacaine | Amide LA |
| Ropivacaine | Amide LA |
| Vesamicol | Presynaptic NM blocker |
| Hemicholinium | Presynaptic NM blocker and Non-competitive ganglion blocker |
| Black widow spider toxin | Presynaptic NM blocker |
| 4-aminopyridine | Presynaptic NM blocker |
| Botulinum toxin A (Botox) & B (Myobloc) | Presynaptic NM blocker |
| Tubocurarine | Non-depolarizing NM blocker and competitive ganglion blocker |
| Pancuronium | Non-depolarizing NM blocker |
| Atacurium | Non-depolarizing NM blocker |
| Alpha-bungarotoxin | Non-depolarizing NM blocker |
| succinylcholine | Depolarizing NM blocker |
| Dantrolene | Skeletal Muscle Relaxant |
| Pyridostigmine | AChE inhibitor |
| Prednisone | Corticosteroid |
| Azathioprine | Purine Biosynthesis inhibitor (antiproliferative agent) |
| Cyclosporine/cyclosporin a | Immunosuppressive - Calcineurin inhibitor |
| Cyclophosphamide | Immunosuppressive |
| Acetylcholine | Non-selective Direct acting cholinergic agonist |
| Carbachol | Non-selective Direct acting cholinergic agonist |
| Bethanechol | Muscarinic receptor selective direct acting cholinergic agonist |
| Pilocarpine | Muscarinic receptor selective direct acting cholinergic agonist |
| Cevimeline | Selective M1 and M3 receptor agonist |
| Nicotine | nicotinic receptor agonist |
| Epibatidine | Nicotinic receptor agonist |
| Edrophonium | AChE inhibitor |
| Neostigmine | AChE inhibitor |
| Parathion | AChE inhibitor - organophosphorus insecticide |
| Diazinon | AChE inhibitor - organophosphorus insecticide |
| Malathion | AChE inhibitor - organophosphorus insecticide |
| Pralidoxime | ChE re-activator |
| Atropine | Antimuscarinic |
| Scopolamine | Antimuscarinic |
| Ipratropium | Antimuscarinic |
| Tiotropium | Antimuscarinic |
| Benztropine | Antimuscarinic |
| Pirenzapine | Relatively Selective M1 receptor antagonist |
| Oxybutnin | M1 and M3 receptor antagonist |
| Tolterodine | M2 receptor antagonist |
| Solifenacin | M3 over M2 and M1 receptor antagonist |
| Trimethaphan | Competitive Ganglion Blocker |
| Mecamylamine | Non-competitive ganglion blocker |
| Epinephrine (adrenaline) | Non-selective adrenergic agonist - Direct acting Sympathomimetic |
| Norepinephrine (noradrenaline) | Non-selective adrenergic agonist - Direct acting Sympathomimetic |
| Dopamine | Subtype selective adrenergic agonist (D1, D2, Beta 1) |
| Dobutamine | Subtype selective adrenergic agonist (Beta 1 and Alpha 1) |
| Phenylephrine | Selective alpha adrenergic agonist |
| Xylometazoline/oxymetazoline | Selective alpha adrenergic agonist |
| Clonidine | Alpha 2 adrenergic agonist |
| Isoproterenol | Beta 2 adrenergic agonist |
| Salbutamol | Beta 2 adrenergic agonist |
| Cyanopindolol | Beta 3 adrenergic agonist |
| Methamphetamine & Amphetamine | indirect acting Sympathomimetic |
| Tyramine | indirect acting Sympathomimetic |
| Ephedrine | indirect acting Sympathomimetic - direct mixed adrenergic agonist (alpha and beta) |
| MAO inhibitors: Selegiline | indirect acting Sympathomimetic |
| Reserpine | indirect acting Sympatholytic |
| Guanethidine | Indirect acting sympatholytic |
| Bretylium | Indirect acting sympatholytic |
| Prazosin | Reversible Competitive alpha 1 antagonist |
| Phentolamine | Non-selective competitive alpha antagonist |
| Phenoxybenzamine | Irreversible alpha 1 antagonist |
| Tamsulosin | Competitive alpha 1A and 1D over 1B antagonist |
| Propranolol | Beta blocker |
| Metoprolol | Beta 1 relative selective blocker |
| Acebutolol | Beta 1 selective antagonist with partial beta 1 agonist |
| Labetalol | Alpha 1 selective blocker (2 isomers) and non-selective beta blocker with some beta 2 agonist (1 isomer) |
| Hydrocortisone | Corticosteroid |
| Triamcinilone | Corticosteroid |
| Betamethasone | Corticosteroid |
| Dexamethasone | Corticosteroid |
| Mifepristone (RU 486) | Glucocorticoid receptor antagonist |
| Tacrolimus | Calcineurin inhibitor |
| Pimecrolimus | Calcineurin inhibitor |
| Sirolimus | Rapamycin (TOR) inhibitor |
| Daclizumab | Interleukin-2 receptor antagonist |
| Basiliximab | Interleukin-2 receptor antagonist |
| Antithymocyte globulin | lymphocyte-depleting agent |
| anti-cd3 antibody/muromonab (OKT-3) | lymphocyte-depleting agent |
| Mycophenolate mofetil | Purine Biosynthesis inhibitor (antiproliferative agent) |
| Leflunomide | Purine Biosynthesis inhibitor (antiproliferative agent) |
| alprostadil | Prostaglandin EP Receptor Agonist |
| Dinoprostone | Prostaglandin EP Receptor Agonist |
| Misoprostol | Prostaglandin EP Receptor Agonist |
| Butaprost | Selective EP2 receptor agonist |
| Sulprostone | Selective EP3 receptor agonist with EP1 activity |
| Lubiprostone | Prostaglandin E Analogue |
| Latanoprost | Prostaglandin F Agonist |
| Prostacyclin | Prostaglandin I Agonist |
| Zileuton | LTRA - 5-lipoxygenase inhibitor |
| Montelukast | LTRA - competitive CystLT1 receptor antagonist |
| Timolol | Beta blocker |
| Levobunolol | Beta blocker |
| Betaxolol | beta 1 selective blocker |
| Apraclonidine | alpha 2 agonist |
| brimonidine | alpha 2 agonist |
| physostigmine | AChE inhibitor |
| Travoprost | Prostaglandin F analogue |
| Bimatoprost | Prostaglandin F analogue |
| Dorzolamide | Topical carbonic anhydrase inhibitor |
| brinzolamide | Topical carbonic anhydrase inhibitor |
| acetazolamide | Oral carbonic anhydrase inhibitor |
| Tazarotene | Selective RAR beta/gamma agonist |
| Adapalene | Selective RAR gamma agonist |
| Bexarotene | Selective RXR agonist |
| Acitretin | Synthetic Non-selective vit A derivative |
| Calcipotriene | Synthetic Vitamin D3 derivative |
| Alefacept | Selective Immunomodulating Antipsoriatic Agent |
| Coal Tar | Antipsoriasis - antiseborrheic |
| Sodium Bicarbonate | Antacid |
| Calcium Carbonate | Antacid |
| Magnesium OH and/or aluminum OH | Antacid |
| Omeprazole | PPI |
| Soraprazan, revaprazan | Potassium competitive acid blockers |
| Ranitidine | H2RA |
| Famotidine | H2RA |
| Sucralfate | Mucosal protective agent |
| Metoclopramide | Dopamine D2 receptor antagonist - prokinetic agent |
| Domperidone | Dopamine D2 receptor antagonist - prokinetic agent |
| Erythromycin | Macrolide antibiotic - prokinetic agent |
| Sulfasalazine | Azo compound |
| 5-aminosalicylic acid (5-ASA) | Azo compound |
| Infliximab | Anti-Tumor necrosis alpha therapy |