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medication delivery

review

QuestionAnswer
suspension of liquid particles in gas Aerosol
device that produces uniform sized particles Nebulizer
device that breaks down large particles baffle
deposition of particles by collision Inertial impaction
retention of particels in the respiratory tract Desposition
measurement of average particle size MMAD
weight or mass produced by a nebulizer Aerosol output
particle size is dependent on substance being nebulized type of nebulizer chosen method used to generate aerosol envoiromental conditions
because medical aerosols contain different size partivles how are they expressed MMAD (measured in micrometers) VMD Volum medican Diameter
particles deposited when they leave suspension in gas deposition
amount of drug inhaled inhaled mass
poportion of drug mass of proper size to reach the lower respiratory tract respirable mass
intertail inpaction sedmentation brownian diffusion aerosol depsosition
suspended partivles in maotion collide and are deposited on the surface, TURBULENT, range of um inertial impaction
particles settle out of suspension and are deposited due to gravity, effects central airway 1-5 um range sedimentation
random drifiting of particles suspened in fluid <3 um, mainly in the respiratory region where bulk gas flow ceases ALVEOLI Diffusion
primary reaction to aerosol drug therapy drug reaction infection airway reactivity
pressurized canister that contains drug, most commonly prescribed aerosol therapy 80% lost 3-6 um produced MDI
autohaler, only medication available this way in the us only pirbuterol ( Maxair) Flow triggered MDI
reduce oropharyngal deposition, reduce need for hand- breath coordination increase pulmonary deposition spacers and holding chamber
simple extention device puts distance between the MDI and patients mouth spacer
incorporates a vavle that prevents the aerosol from being cleared by patient's exhalation holding chamber
breath actuated, meter dosing system patient creats aerosol particle size 1-2 um deposited in oropharynx DPI
Spinhaler intal
rotahaler albuterol
flexhaler pulmicort
diskus advair, serevent
aerolizer foradil
twisthaler asmanex
handihaler spiriva
produces aerosol droplets in range of 0.1-500um powered by high pressure stream, MOST Commom SVN
continuous delivering treatment, high- output aerosol MMAD 2.2-3.5um, slowly opens airways TX Q 20-30min LVN, Heart, Hope
specificaly for Ribavirin to treat RSV, Toxic to unborn fetus particle size of 1.2-1.4um SPAG
caplable of higher aerosol outputs USNs
Does not add extra flow to the ventilator small volume USNs
used mailnly for bland aerosoltherapy or sputum induction Large volum USNs
used to administer medication to upper airway ( nasal, pharynx, larynx) medication deliverd here before bronchoscopy hand- bulb atomizer
thumb control in compressed air line allows patient to divert gas flow to the nebulizer during inspiration only BEN breath enhanced nebuliers
sense inpiration and pulse airflow to jet orifice Dosimeters (BANs)
breath actuated jet nebulizer nebulizer ceases when patient's inspiratory flow decreases below a certain point aeroeclipse
monitors pressure changes and inspiratory time for the first 3 consecutive breaths, audible signal sounds AAD
pre assessment breath sounds HR, RR, quality , cough spo2 WOB, SOB peak flow rate
Post assessment breath sounds HR, RR, quality, cough, aptients response to thearapy, WOB, SOB peak flow rate SPO2
what should you do during treatment communicate with the patient
Created by: latoswats