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medication delivery
review
| Question | Answer |
|---|---|
| suspension of liquid particles in gas | Aerosol |
| device that produces uniform sized particles | Nebulizer |
| device that breaks down large particles | baffle |
| deposition of particles by collision | Inertial impaction |
| retention of particels in the respiratory tract | Desposition |
| measurement of average particle size | MMAD |
| weight or mass produced by a nebulizer | Aerosol output |
| particle size is dependent on | substance being nebulized type of nebulizer chosen method used to generate aerosol envoiromental conditions |
| because medical aerosols contain different size partivles how are they expressed | MMAD (measured in micrometers) VMD Volum medican Diameter |
| particles deposited when they leave suspension in gas | deposition |
| amount of drug inhaled | inhaled mass |
| poportion of drug mass of proper size to reach the lower respiratory tract | respirable mass |
| intertail inpaction sedmentation brownian diffusion | aerosol depsosition |
| suspended partivles in maotion collide and are deposited on the surface, TURBULENT, range of um | inertial impaction |
| particles settle out of suspension and are deposited due to gravity, effects central airway 1-5 um range | sedimentation |
| random drifiting of particles suspened in fluid <3 um, mainly in the respiratory region where bulk gas flow ceases ALVEOLI | Diffusion |
| primary reaction to aerosol drug therapy | drug reaction infection airway reactivity |
| pressurized canister that contains drug, most commonly prescribed aerosol therapy 80% lost 3-6 um produced | MDI |
| autohaler, only medication available this way in the us only | pirbuterol ( Maxair) Flow triggered MDI |
| reduce oropharyngal deposition, reduce need for hand- breath coordination increase pulmonary deposition | spacers and holding chamber |
| simple extention device puts distance between the MDI and patients mouth | spacer |
| incorporates a vavle that prevents the aerosol from being cleared by patient's exhalation | holding chamber |
| breath actuated, meter dosing system patient creats aerosol particle size 1-2 um deposited in oropharynx | DPI |
| Spinhaler | intal |
| rotahaler | albuterol |
| flexhaler | pulmicort |
| diskus | advair, serevent |
| aerolizer | foradil |
| twisthaler | asmanex |
| handihaler | spiriva |
| produces aerosol droplets in range of 0.1-500um powered by high pressure stream, MOST Commom | SVN |
| continuous delivering treatment, high- output aerosol MMAD 2.2-3.5um, slowly opens airways TX Q 20-30min | LVN, Heart, Hope |
| specificaly for Ribavirin to treat RSV, Toxic to unborn fetus particle size of 1.2-1.4um | SPAG |
| caplable of higher aerosol outputs | USNs |
| Does not add extra flow to the ventilator | small volume USNs |
| used mailnly for bland aerosoltherapy or sputum induction | Large volum USNs |
| used to administer medication to upper airway ( nasal, pharynx, larynx) medication deliverd here before bronchoscopy | hand- bulb atomizer |
| thumb control in compressed air line allows patient to divert gas flow to the nebulizer during inspiration only | BEN breath enhanced nebuliers |
| sense inpiration and pulse airflow to jet orifice | Dosimeters (BANs) |
| breath actuated jet nebulizer nebulizer ceases when patient's inspiratory flow decreases below a certain point | aeroeclipse |
| monitors pressure changes and inspiratory time for the first 3 consecutive breaths, audible signal sounds | AAD |
| pre assessment | breath sounds HR, RR, quality , cough spo2 WOB, SOB peak flow rate |
| Post assessment | breath sounds HR, RR, quality, cough, aptients response to thearapy, WOB, SOB peak flow rate SPO2 |
| what should you do during treatment | communicate with the patient |