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Pharmacology Test

QuestionAnswer
Drug any chemical substance that produces a biologic response in a living system
Ampule sealed glass container designed to hold a single dose of a drug.
Vial small glass bottle with a sealed rubber cap
Medication Properties absorption, distribution, metabolism, excretion,pharmacokinetics,bioavailabilty
Absorption process by which a drug enters the systemic circulation in order to provide a desired effect
Distribution means by which a drug travels from the site of absorption to the site of action, usually through the blood stream.
Metabolism process by which the body transforms drugs into an inactive form that can be excreted through the body.
Excretion elimination of drugs from the body after they have been metabolized. (primarily by the kidneys)
Pharmacokinetics how drugs enter the body, are absorbed, reach their site of action, are matabolized, and exit the body
Bioavailabity when a drug must be absorbed and taken via the bloodstream to its intended site in order to act
The amount of time needed to absorb a drug and the extent to where it becomes bioavailable deoends on ___? Route of administration, GI Motility, Dosage Form, Interaction with food & other drugs
Medication Effect: Therapeutic effect predictable physiological response
Side Effect response other than the desired effect
Adverse Effect Unwanted "bad" effect, Meperdine (demerol) frequently produces nausea & vomiting
Toxic Effect developes when a drug accumulates in a body beacause of inadequate excretion, impaired metabolism, overdose, or drug sensitivity.
Idiosyncratic Effect When a pt over or under reacts to a drug or has an unusual reaction
First-pass Effect Partial metabolism of a drug before it reaches systemic circulation
Clearance Rate A drug's removal from the body
Biological Half Life time required for a current serum drug concentration to decline by 50% (half life of heparine is 90 min while half life of coumadin is 48hrs) Liver function can effect half life.
Allergic Reaction results from an immune medicattion response by the body against the drug and is not necessarily related to dose.
Drug-Drug interaction occurs when 2 or more drugs act in unison, may produce bad effects (contrast & metformin) or may produce a synergistic effect (alcohol & valum) where the sedative properties of the 2 drugs could combine and cause a comatose state
FDA Federal agency that is responsible for protection against fraudulent claims by manufactures or merchants of foods or drugs, allows the name to be shortened for ease of memory. Food & Drug Administration
Legend Drugs Medications that require a prescription
7 Components of a Prescription Pt name, id#, rm#, or address; drug name (generic or brand); dosage;dosage form; route of administration; date order is written; prescribers signature
Verbal Order an order that is verbally recieved form a physician & transcribed to an order form, must be signed.
Drug Classifications Chemical name, Generic name, Brand/Trade name
Controlled substances Meds that have high potential for abuse; classified by "C", roman numerals donates class, range from C-1 through C-V
C-1 drugs opium, heroin, cocaine= illegal
C-V Drugs Can be purchased OTC w signature
C-11 drugs only legal with prescription; high potentail for abuse, stored under lock & key (morphine, fentanyl, & oxycodone)
Analgesics Drugs that releive pain without causin LOC. Non-narcotics used to treat pain (tylenol,acetaminophen), & treat inflammation (ibuprofen-advil, naproxen-aleve)
Analgesics-Narcotics stimulate CNS receptors & cause decrease in the preception of pain. Highly addictive, cause N&V, require prescription. (Morphine, Demerol, fentanyl)
Anesthetics Act on CNS to cause loss of sensation.
General aneshesia produces muscle realxion & LOC
Local Anesthesia Blocks the nerve conduction from the area to the CNS. (Lydocaine-Xylocaine)
Antianxiety Calms pt without depressing CNS, or elevates pt mood without depressing CNS, may cause physiologic dependecy with prolonged use & possible sever withdrawel reactions. (Diazepam-Valum)
Antiarrythmics Used to treat variations from normal heart beat. (lidocaine-xylocaine, verapamil-Veraptin, Adenosine-Adenocard, Digoxin-Lanoxsin)
Antiobiotics Destroy or inhibit the growth of microorganisms, pt may have an allergic reaction. (erythromycin-Erthrocin)
Anticholinergics Reduce smooth muscle tone, motility of the GI tract, and secretions from the respiratory tract and secretory glands, Cause dry mouth and decreased perspiration, High doses may produce serious side effects; delirium, rapid heart beat, and coma. Belladona
Anticoagulants Inhibits blood clotting or increases coagulation time. Heparine(Hep-Lock) givin IV,Warfarin(Coumadine) oral tablet, enoxaparin(Lovinox)subQ
Anticonvulsants prevents or controlls seizures. Clonazpam(klonopin)-petit mal seizures, phenytoin(Dilantin)-grand mal seizures, Lorazpam(Ativan)
Antidepressants used to treat clinical depression, enhance levels of seratonin & norepinephrine, may cause dependency.Prozac, zoloft
Antidiabetic Required for patients that have difficulty maintaining the proper balance between blood sugar and tissue sugar,Insulin dependent (Type I)-have little or no circulating endogenous insulin,Most take insulin and require regular meals to keep their blood suga
Created by: 1563670857
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