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antihypertensives
ch. 25 pharm
| Question | Answer |
|---|---|
| Blood pressure = | CO X SVR(systemic vascular resistance) |
| Which class of heart drugs work best on whites | B-blockers and ACE inhibitors |
| which class of heart drugs work best on blacks | CCBs adn diuretics |
| hypertension is known cause in how many cases | 10% |
| What are the categories that are antihypertensive | adrenergic drugs, ACE inhibitors, ARB's, CCB's, diurectics, vasodilators |
| what is the drug of choice for pregnant | methyldopa(Aldomet) |
| What is clonidine | Adrenergic a2 receptor agonists |
| what do beta blockers do | reduce BP by blocking b1 receptors, reduce renin secretion, reduce peripheral vascular resistance |
| what is the only centrally and peripherally acting neuron blocker | reserpine, not widely used in US |
| Why are captopril adn linsinopril NOT prodrugs | They do not need to be metabolized by live, so good for liver dysfunction |
| What do ARB's do | block vasoconstriciton and release of aldosterone |
| What are ARB's | losartan valsartan eprosartan irbesartan "The Sartans r potent vasodilators |
| what are CCB's | benzothiazepines phenylalkamine dihydrophyridine "Calcium Channel Nine" |
| What do CCB's treat | angina,hypertension, dysrhythmias, migraines, raynaud's disease |
| what do vasodilators really do | relax arteriolar/venous smooth muscle |
| what should men know about antihypertensives | impotence |