Help
Options
Didn't know it?
click below
click below
Knew it?
click below
click below
Don't Know
Remaining cards (0)
Know
retry
shuffle
restart
0:00
Embed Code - If you would like this activity on your web page, copy the script below and paste it into your web page.
Normal Size Small Size show me how
Normal Size Small Size show me how
Antidysrhythmic drug
Ch. 23 Pharm
| Question | Answer |
|---|---|
| What are internodal pathways (Bachmann bundle)? | pathways in atria carry electrical impulses generated by SA node, cause heart to beat. |
| Inside a cardiac cell has a + or - charge? Outside cell? | Negative positive |
| What is the RMP resting membrane potential? Is this polarization or depolarization? | difference b/c electronegative charge from uneven distr of Na, K, Cl x cell membrane polarization |
| At RMP, K ions are more inside or outside cell? | intracellularly, Na and K are intracellularly concentrated |
| What happens when there is a change in ion distribution x membranes, it creates a what? | action potential |
| AP has 5 phases | phase 0,1,2,3,4,5 |
| When is depolarization? | phase 0-upstroke, influx of Na ions, |
| When is repolarization? | phase 1, 2, 3 to 4 |
| The period b/n phase 0 and phase 3 is called | effective refractory period, cardiac cell can't be restimulated to depolarize adn generate AP |
| Which node is natural pacemaker of heart? | SA node |
| What system is used to classify antidysrhythmiic drugs? | Vaughan Williams Classification 4 classes |
| dysrhythmias that originate outside the conduction system are called | ectopic |
| Name Class II drugs | beta blockers: atenolol, esmolol, metaprolol, propranolol "Oh lol, i can't go" |
| What do Class II drugs do for dysrhythmia? | block sympathetic stimulation to heart |
| Name an unclassified antidysrhythmic drug | adenosine (Adenocard) |
| What are features of adenosine | very short half life, less than 10 seconds may stop asystole, stop heart |
| Antidysrhythmic adverse effects | All can cause dysrhythmias, prolonged QT |
| Class I drugs, you should monitor what? Name a Class I drug? | ECG for QT intervals prolonged more than 50% moricizine, lidocaine |
| How should lidocaine be adm if they contain epinephrine? | Only given as local, not as IV |
| Notify doctor if these happen with antidysrhythmia drugs | SOB, edema, dizziness, syncope, chest pain, GI distress, blurred vision |
| what does grapefruit juice do with antidysrhymias? | inhibit metabolism |
| Is metoprolol and atenolol cardioselective or nonselective? Which Class? | Class II, cardioselective, treatment of hypertension and angina too Contraindications: severe bradycardia |
| Propranolol is cardioselective or nonselective? | nonselective, blocks beta 1 and beta 2 adrenergic receptors in heart and lungs |
| A class III drugs? | amiodarone, sotalol (Class II props) used for life threatening vent. tachycardia/fibrillation, atrial fib resistant to other drugs |
| Class IV drugs | verapamil, diltiazem ca channel blockers, reduce AV node conduction |
| Therapeutic effects for antidysrhythmic drugs |
Created by:
palmerag
Popular Pharmacology sets