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Cardiovascular Drugs
| Question | Catecholamine (A1, A2, B1, B2) |
|---|---|
| Norepinephrine | Catecholamine (A1, A2, B1) |
| Isoproterenol | Catecholamine (B1, B2) |
| Dobutamine | (Catecholamine (B1) |
| Dopamine | Catecholamine (B1; A1 at high doses) |
| Ephedrine | Non-catecholamine (A1, A2, B1, B2) |
| Phenylephrine | Non-catecholamine (A1) |
| Terbutaline | Non-catecholamine (B2) |
| Alpha-1 activation | Vasoconstriction, mydriasis |
| Alpha-2 activation | Primarily CNS |
| Beta-1 activation | Increased HR, increased contractility, increased AV conduction |
| Beta-2 activation | Smooth muscle relaxation |
| Dopamine activation | Dilation of renal vasculature |
| Alpha-1 selective antagonists | Terazosin, Doxazosin, Prazosin |
| Beta-1 non-selective antagonists (HINT: first generation) | Nadalol, Propanolol |
| Mixed alpha/beta antagonists (HINT: third generation) | Carvedilol, Labetalol |
| Beta-1 selective antagonists (HINT: second generation) | Metoprolol, Atenolol |
| Alpha-1 non-selective antagonist | Phentolamine |
| Catecholamines | Epinephrine, Norepinephrine, Isoproterenol, Dopamine, Dobutamine |
| Non-catecholamines | Ephedrine, Phenylephrine, Terbutaline |
| Loop diuretics | Furosemide (Lasix) |
| Thiazide diuretics | Hydrochlorothiazide (HydroDiuril, etc.) |
| Potassium-sparing diuretics | Spironolactone (Aldactone), Eplerenone (Inspra) |
| ACE inhibitors | Lisinopril (Zestril), Captopril |
| ARBs (Angiotensin II Receptor Antagonists) | Losartan (Cozaar) |
| Aldosterone Agonists | Spironolactone (Aldactone), Eplerenone (Inspra) |
| Nifedipine (Adalat) | Dihydropyridine calcium-channel blocker |
| Verapamil (Isoptin) | Non-dhydropyridine calcium-channel blocker |
| Vasodilators (include...) | ACE-inhibitors, ARBs, calcium-channel blockers (CCBs), sympatholytics, organic nitrates |
| Hydrochlorothiazide | Thiazide diuretic; first line treatment for HTN |
| Lisinopril (Zestril) | ACE inhibitor |
| Losartan (Cozaar) | ARB |
| Carvedilol (Coreg) | Beta blocker |
| Digoxin (lanoxin) | Inhibits Na-K ATPase |
| Metoprolol (Lopressor) | Beta blocker |
| Clopidogrel (Plavix) | Antiplatelet |
| Heparin | Anticoagulant |
| Enoxaparin (Lovenox) | LMWH; anticoagulant |
| Warfarin (Coumadin) | Anticoagulant |
| Alteplase (Activase) | Thrombolytic |
| Ezetimibe (Zetia) | Decreased cholesterol absorption |
| Niacin | Decreased VLDL production |
| Gemfibrozil (Lopid) | Decreased VLDL production |
| Pravastatin (Pravachol) | Decreased cholesterol synthesis |
| Lidocaine (Xylocaine) | Antidysryhthmic (Na channel blocker) |
| Propanalol (Inderal) | Non-selective beta blocker |
| Amiodarone (Cordarone) | Antidysrhythmic (K channel blocker); IV or PO |
| Adenosine (Adenocard) | Antidysrhythmic (inhibits cAMP-induced Ca influx) |