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Laxative

QuestionAnswer
Laxatives are also called cathrtic
Laxatives are used in several ways to speed the passage of the intestinal contents throught the GI tract
Laxatives can be... chemical, bulk stimulants, or lubricants
Chemical Laxatives irritate the linning of the GI tract
Bulk Laxatives cause the fecal matter in increase in bulk. also called mechanical stimulants
Lubricant Laxatives help the intestinal contents move more smoothly
Chemical Stimulants drugs are: cascara (generic), senna (Senokot), castor oil (Neoloid), bisacodyl (Dulcolax)
Chemical Stimulants work to stimulate the nerve plexus in the intestinal wall, causing increaded movement and the stimulation of local reflexes
cascara generic
cascara (generic) reliable agent, intestinal evacuation, slow steady effect or cause sever cramping and rapin evacuation of contents in the lg intestines
senna Senokot
senna (Senokot) similar to cascara, it is found in many OTC preparations
castor oil Neoloid
castor oil (Neoloid) old standby, use when thorough evacuation of the intestine is desired. Begins at the sm intes, and increase throughout. blocks absorption of fats and fat soluable vitamins. may lead to constipation from exhaustion, when there is no stimulus to movemen
bisacodyl Dulcolax
bisacodyl (Dulcolax) OTC slow & steady incrase in movement of the lg intest, drug of choice if mild stimulation is needed to prevent constipation and straining after GI surgery or MI
Bulk Stimulants rapid acting, aggressive laxative, increases motility of GI tract by increasing fluid in intestinal contents, which enlarge bulk, stimulate local strech receptors and activates localy
magnesium sulfate Epson salt
magnesium sulfate (Epson salt) potent laxative, when evacuation of the GI tract in needed rapidly, in cases of poisioning. Acts by exerting a hypertonic pull aganist the mucosal wall, drawing fluid into the intestinal contents
magnesium citrate Citrate of Magnesia
magnesium citrate (Citrate of Magnesia) found in citrus flavored base, stimulate the bowel evacuation before GI test
magnesium hydroxide Milk of Magnesia
magnesium hydroxide (Milk of Magnesia) stimulate bulk is milder and slower acting, it has a saline pull
lactulose Chronulac
lactulose (Chronulac) alternative choice for pt w/cardiovascular problems. The saltless osmotic laxative pulls fluid out of the venous system and into the lumen of the sm intest
polycarbophil FiberCon
polycarbophil (FiberCon) forms gelatin like bulk. mild and less irritating. Drink plenty of water. it may swell the esophagus into a gelating like mass and obstruct the esophague causing problems if you don't drink enough water
psyllium Metamucil
psyllium (Metamucil) gelatin like bulk stimulant
polyethylene glycol electrolyte solution Go-lytely
polyethylene glycol electrolyte solution (Go-lytely) used to clean bowel before a GI exam, has osmotice effect
Lubricating Laxatives work to... make defecation easier without stimulating the movement of the GI tract
Lubricating Laxatives help pt with... hemorrhoids, and pt who recently had rectal surgery
docusate Colace
docusate (Colace) detergent action on the surface of the intestional bouls. Used for pt who had surgery, MI, or obstetrical delivery
glycerin Sani-Supp
glycerin (Sani-Supp) suppository form evacuates the rectum w/o affecting the GI tract
mineral oil Agoral Plain
mineral oil (Agoral Plain) oldest of the laxatives. not absorbed and forms a slippery coat on the contents,interfers with the absorption of fat soluable vitamins A, D, E, & K
Bulk Stimulant drugs: magnesium sulfate (Epsom salts), magnesium citrate (Citrate of Magnesia), magnesium hydroxide (Milk of Magnesia), lactulose (Chronulac), polycarbophil (FiberCon), psyllium (Metamucil), polyethylene glycol electrolyte solution (Go-lytely)
Lubricating Laxatives drugs: docusate (Colace), glycerin (Sani-Supp), mineral oil (Agoral Plain),
Laxatives are contraindications in... acute abdominal disorders, including appendicitis, diverticulitis, and ulcerative colitis. Preg/lac. Some can precipiate labor, CPEBM
Laxative adverse effects are... in the CNS weakness, related to loss of fluid and electrolyte imbalance. Sweating, palpations, flushing, fainting.
Cathartic dependence is a common effect in laxatives it is.... when pt over use laxatives for a long period of time, the GI tract bc dependent on the vigorous stimulation of the laxative. w/o it the GI tract may not move for a period of time which could lead to constipation or drying of the stool or impaction.
Created by: jessinms
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