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Laxative
| Question | Answer |
|---|---|
| Laxatives are also called | cathrtic |
| Laxatives are used in several ways | to speed the passage of the intestinal contents throught the GI tract |
| Laxatives can be... | chemical, bulk stimulants, or lubricants |
| Chemical Laxatives | irritate the linning of the GI tract |
| Bulk Laxatives | cause the fecal matter in increase in bulk. also called mechanical stimulants |
| Lubricant Laxatives | help the intestinal contents move more smoothly |
| Chemical Stimulants drugs are: | cascara (generic), senna (Senokot), castor oil (Neoloid), bisacodyl (Dulcolax) |
| Chemical Stimulants work to | stimulate the nerve plexus in the intestinal wall, causing increaded movement and the stimulation of local reflexes |
| cascara | generic |
| cascara (generic) | reliable agent, intestinal evacuation, slow steady effect or cause sever cramping and rapin evacuation of contents in the lg intestines |
| senna | Senokot |
| senna (Senokot) | similar to cascara, it is found in many OTC preparations |
| castor oil | Neoloid |
| castor oil (Neoloid) | old standby, use when thorough evacuation of the intestine is desired. Begins at the sm intes, and increase throughout. blocks absorption of fats and fat soluable vitamins. may lead to constipation from exhaustion, when there is no stimulus to movemen |
| bisacodyl | Dulcolax |
| bisacodyl (Dulcolax) | OTC slow & steady incrase in movement of the lg intest, drug of choice if mild stimulation is needed to prevent constipation and straining after GI surgery or MI |
| Bulk Stimulants | rapid acting, aggressive laxative, increases motility of GI tract by increasing fluid in intestinal contents, which enlarge bulk, stimulate local strech receptors and activates localy |
| magnesium sulfate | Epson salt |
| magnesium sulfate (Epson salt) | potent laxative, when evacuation of the GI tract in needed rapidly, in cases of poisioning. Acts by exerting a hypertonic pull aganist the mucosal wall, drawing fluid into the intestinal contents |
| magnesium citrate | Citrate of Magnesia |
| magnesium citrate (Citrate of Magnesia) | found in citrus flavored base, stimulate the bowel evacuation before GI test |
| magnesium hydroxide | Milk of Magnesia |
| magnesium hydroxide (Milk of Magnesia) | stimulate bulk is milder and slower acting, it has a saline pull |
| lactulose | Chronulac |
| lactulose (Chronulac) | alternative choice for pt w/cardiovascular problems. The saltless osmotic laxative pulls fluid out of the venous system and into the lumen of the sm intest |
| polycarbophil | FiberCon |
| polycarbophil (FiberCon) | forms gelatin like bulk. mild and less irritating. Drink plenty of water. it may swell the esophagus into a gelating like mass and obstruct the esophague causing problems if you don't drink enough water |
| psyllium | Metamucil |
| psyllium (Metamucil) | gelatin like bulk stimulant |
| polyethylene glycol electrolyte solution | Go-lytely |
| polyethylene glycol electrolyte solution (Go-lytely) | used to clean bowel before a GI exam, has osmotice effect |
| Lubricating Laxatives work to... | make defecation easier without stimulating the movement of the GI tract |
| Lubricating Laxatives help pt with... | hemorrhoids, and pt who recently had rectal surgery |
| docusate | Colace |
| docusate (Colace) | detergent action on the surface of the intestional bouls. Used for pt who had surgery, MI, or obstetrical delivery |
| glycerin | Sani-Supp |
| glycerin (Sani-Supp) | suppository form evacuates the rectum w/o affecting the GI tract |
| mineral oil | Agoral Plain |
| mineral oil (Agoral Plain) | oldest of the laxatives. not absorbed and forms a slippery coat on the contents,interfers with the absorption of fat soluable vitamins A, D, E, & K |
| Bulk Stimulant drugs: | magnesium sulfate (Epsom salts), magnesium citrate (Citrate of Magnesia), magnesium hydroxide (Milk of Magnesia), lactulose (Chronulac), polycarbophil (FiberCon), psyllium (Metamucil), polyethylene glycol electrolyte solution (Go-lytely) |
| Lubricating Laxatives drugs: | docusate (Colace), glycerin (Sani-Supp), mineral oil (Agoral Plain), |
| Laxatives are contraindications in... | acute abdominal disorders, including appendicitis, diverticulitis, and ulcerative colitis. Preg/lac. Some can precipiate labor, CPEBM |
| Laxative adverse effects are... | in the CNS weakness, related to loss of fluid and electrolyte imbalance. Sweating, palpations, flushing, fainting. |
| Cathartic dependence is a common effect in laxatives it is.... | when pt over use laxatives for a long period of time, the GI tract bc dependent on the vigorous stimulation of the laxative. w/o it the GI tract may not move for a period of time which could lead to constipation or drying of the stool or impaction. |