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ex-ulcer drugs
anitpeptic, prostaglandin, dig enzymes
| Question | Answer |
|---|---|
| Antipeptic agent sucralfate (Carafate) works to... | protect eroded ulcer sites in the GI tract from further damage by acid and degestive emzymes |
| Antipeptic agent--therapeutic agents | prevents further breakdown of the area and promotes healing |
| Antipeptic agent Contraindictions | know alergy, pt w/renal failure, bc of bild up of aluminum caution w/preg/lac |
| Antipeptic agent Adverse effects | Constipation is the most frequently seen adverse effect. Diarrhea, nausea, indigestion, gastric discomfort, and dry mouth |
| Antipeptic agent Drug/Drug Interaction | If aluminum salts are combined w/sucralfate, there is a risk of high aluminum levels and aluminum toxicity. Wait 2 hrs bt drugs |
| Prostaglandin | is used to protect the linning in the stomach in situations that might lead to serous GI complications |
| misoprostol | Cytotec |
| misoprostol (Cytotec) | is used to prevent NSAID induced gastric ulcers in pt who are at high risk for complications from a gastric ulcer |
| Prostaglandin work to | increase gastric acid secretions and increase bicarbonate and mucous produciton in the stomach, thus protecting the linning |
| Prostaglandin found to be effective treatment for ulcers in pt who... | dont respond to H2 antagonists. |
| Prostaglandin contraindictions | in pregnancy. It is an abortifacient. Women of child bearing age should be advised to have a negative preg test w/in 2 wks of treatment |
| Prostaglandin adverse effects | GI effects: nausea, diarrhea, abdominal pain, flatulence, vomiting. Genitourinary effects: miscarriages, excessive bleeding, menstrual disorders |
| Digestive enzymes help pt who have | suffered a stroke, salivary gland disorders, or extreme surgery of the head or neck or cystic fibrosis or pancreatic dysfunction |
| saliva substitute | MouthKote, Salivart |
| saliva substitute (MouthKote, Salivart) | help in conditions of dry mouth, stroke, radiation therapy, chemotherapy, other illness |
| pancreatin | Creon Capsules |
| pancreatin (Creon Capsules) | is used to aid the digestion and absorption of fats, proteins, and carbs |
| pancrelipase | Cotozym, IIozyme |
| pancrelipase (Cotozym, IIozyme) | is used like pancreatin in conditions that lack pancrelipase |
| Digestive enzymes Contraindications | caution w/pt w/CHF. Pancreatic enzymes should not be used w/known alergy to pork products |
| Digestive enzymes Adverse effects | complications from abnormal electrolyte absorption, such as increased levels of magnesium, sodium, or potassium. Most offten occur w/pancreatic enzymes are related to GI irritation and nausea, cramps, and diarrhea |