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Pharmacology tammie

chapter 2

What is an agonist Chemical that binds to a receptor and creates an effect on the body
What is Synergism Two drugs given together have a greater effect than when alone
Tachyphylaxis Rapid decrease in response to a drug
Enteral route Literally means small intestines
Parenteral Any route except enteral: IV etc
Pharmacokinetic phase time a drug takes to be absorbed, distributed and eliminated from body
Bioavailability % of drug that reaches systemic circulation
First-pass effect effect of liver on a drug
Factors affecting Lung availability/total systemic availability 1. Efficiency of device used 2. Inhaled drugs with firs-pass effect 3. Mouthwashing 4. Use of a reservoir
Potency Concentration or dose of drug that produces 50% of the drugs max response.
Pharmacogenetics Hereditary differences in the way the body handles specific drugs
Idiosyncratic effect effect that is opposite of the expected, or absent
Created by: kulmax2004