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Pharmacologytammie 4

Central and Peripheral Nervous system.

Andrenergic Drug that stimulates receptors for epinephrine or epinephrine.
Parasympathetic system Controls SLUD
Sympathetic fight or flight system
What are the 2 major control systems in the body 1. Nervous 2. Endocrine
Function of sensory(afferent) neurons detect change in light, heat, pressure, pain in CNS
Somatic(motor)neurons responsible for voluntary muscle movements
ANS Involuntary, unconscious control mechanism of body
What is the Neurotransmitter at the Parasympathetic end Acetycholine (strong bronchoconstrictor)
Neurotransmitter at the sympathetic end norepinephrine/epinephrine
What terminates acetylcholine & norepinephrine cholinesterase & catechol-0-methyltransferase( COMT) and MAO - monoamine oxidase respectively.
Effects of parasympathetic system on the cardiopulmonary 1. Decreased heart rate 2. Low BP 3. Bronchoconstriction 4. Mucus secretion
Muscarinic Receptors at parasympathetic end. M3 is on airway smooth muscle mediating bronchoconstriction.
Atropine Typical parasympatholytic or anticholinergic. Blocks parasympathetic site
Sympathetic effects on the cardiopulmonary system 1. Increased heart rate 2. Increase BP 3. Bronchodilation 4. Increased secretion from mucus glands in the airway.
Sympathetic end receptors Alpha - vasoconstriction B1 - Inc heart rate B2 - Smooth muscle relaxation
drugs refer to page 95 pg 95
What is the neurotransmitter at the sympathetic end Epinephrine
Sympatholytics(Adrenergic blocking agents) - inhibits the SNS -
Created by: kulmax2004