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muscloskeletal 68q

extra 68Q

QuestionAnswer
MOA: Inhibits bone resorption SE: Patients may experience localized skin reaction to the injection or systemic reaction if allergic to salmon Calcitonin - Miacalcin Nasal Spray, Fortical Nasal Spray
MOA: Provides calcium for bone formation U: treats post menopausal osteoporosis and prevention of progressive bone loss Calcium Carbonate - Oscal
SE: Hot flashes Peripheral edema leg cramps/muscle spasm Raloxifene - Evista
DI: Take with food or milk Avoid aspirin May cause drowsiness Do not drink alcohol SE: G.I. Upset All NSAIDS
Use: Anti-inflammatory, Analgesic, 1st line for gouty arthritis Indomethacin - Indocin
Use: Anti-Inflammatory & Analgesic ~also marketed as immediate release Potassium Salt (Cataflam) Diclofenac - Voltaren
Uses: Osteoarthritis, Rheumatoid arthritis and Juvenile Rheumatoid arthritis Meloxicam - Mobic
Considered a Schedule III-V drug Commanders will consider it a locally controlled item Fiorinal
Considered a Schedule III-V drug Isometheptene Mucate, Dichloralphenazone, Acetaminophen - Midrin
Intoxication or poisoning due to an overdose or excessive use of the ergot alkaloids is known as ........... Ergotism
Use: Abort or prevent vascular headaches (migraines) Controls effectively up to 70% of acute migraine attacks *contraindicated in pregnancy* SE: Vertigo, itching, nausea and vomiting Ergotamine Tartrate - Ergomar
Migranal is a ____________ DHE45 is a ______________ nasal preparation injectable
A new class of anti-migraine agents that work primarily on the serotonin receptor causing cerebral vasoconstriction Triptans
MOA: Reduces the production of uric acid Allopurinol - Zyloprim, Aloprim
MOA: Increases urinary excretion of uric acid Probenecid - Benemid
What does DMARD stand for? Disease Modifying Anti-Rheumatic Drug
Agents that completely block nerve impulses to skeletal muscles causing complete skeletal muscle relaxation Neuromuscular Blocking Agents
Agents cause complete blocking of nerve impulses so most pharmacists do not strictly consider them skeletal muscle relaxants Neuromuscular Blocking Agents
When nerve impulses that stimulate skeletal muslce tone become blocked at the spinal cord and results in diminished skeletal muscle tone Skeletal Muscle Relaxation
Three major categories of skeletal muscle relaxants Neuromuscular Block Agents Centrally Acting Agents Direct Acting Agents
The onset of blockade is usually rapid as motor weakness gives way to total flaccid paralysis
What 2 drugs are short acting NMBs with an onset of ~1 minute and a duration of action less than 30 minutes? Mivacurium - Mivacron Rapacuronium - Raplon
An acetylcholinesterase inhibitor used to antagonize or reverse the action of these agents Neostigmine - Prostigmin
MOA: acts like an excess of acetylcholine at NM junction to depolarize the muscle receptor site and prevent its repolarization-causes an initial muscle contraction Depolarizing blocking agents
Use: ultra-short acting neuromuscular blocking agent used as an adjunct to anesthesia or for rapid sequence intubation (short procedures Is the only depolarizing agent approved for use in the U.S. Succinylcholine - Anectine, Quelicin
Use: Muscle spasticity and rigidity associated with multiple sclerosis or cerebral palsy, also spinal cord injuries SE: Frequent urination Baclofen - Lioresal
MOA: Reduces skeletal muscle tone through a direct effect on contraction. Direct Acting Skeletal Muscle Relaxants
Uses: Treatment of malignant hyperthermia Dantrolene - Dantrium
Uses: Analgesic: drug of choice for myocardial infarction, severe pain from terminal cancer, and pain associated with pulmonary edema Morphine - MS Contin, Oramorph, Roxanol, Duramorph
Uses: Antitussive and Analgesic Codeine
Uses: Maintenance treatment of narcotic addiction Methadone - Dolophine
Uses: Mirgraine headache Stadol
Primary military use DI: Take with food to minimize GI upset Naltrexone - Revia
Use: chronic alcoholism SE: garlic or metallic like taste DI: avoid alcohol and alcohol containing products Disulfiram - Antabuse
Cautions: Head Injury-increase intracranial pressure Asthma-possible respiratory depression Combination with other CNS depressants-potentiation Use of Narcotics
Comes in many combinations Scheduled drug Codeine with Acetaminophen - Tylenol #3
General Properties: Analgesia Antitussive Mood Alteration Gastronintestinal Effects Narcotic Analgesics
MOA: Interneuronal blocking agents, their limited efficacy (effects) may be due solely to general depression of the CNS SE: CNS Depression (drowsiness) Dizziness Centrally Acting Skeletal Muscle Relaxants
Created by: lacythecoolest
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