Help
Options
Didn't know it?
click below
click below
Knew it?
click below
click below
Don't Know
Remaining cards (0)
Know
retry
shuffle
restart
0:00
Embed Code - If you would like this activity on your web page, copy the script below and paste it into your web page.
Normal Size Small Size show me how
Normal Size Small Size show me how
MCPHS AntiBac Exam 1
| Question | Answer |
|---|---|
| MRSA/E Meds? | Vancomycin, Daptomycin, Linezolid, Synertid |
| Enterococcus Meds? | Amp., Amox., Pipracillin; PCN (not reliable) |
| Ceph's don't cover? | MRSA/E's or Eterococcus |
| Pseudomona Meds? | Ceftazidime, Cefepime, Piperacillin, BLIC's, Ticar, Imipen/Meropenum, Aztreonam, Florouinolones (Cipro, Ofloxacin, Levofloxacin ) |
| Hos. Aquired MRSA/E Meds? | Synrcid, Linezolid, Daptomycin |
| Quinolones (UTI's): | Norfloxacin (only UTIs), Ciprofloxacin, Ofloxacin, Levofloxacin, Gatifloxacin, Moxifloxacin (Not for UTIs) |
| Newer Quinolones for? | Gm(+) S. Pneumonia, Respir/Atypicals, All Good for Gm(-) |
| Telithromycin (Ketek)? | Structually Related to Erithromycin, Sim. to Macrolides vs. Pulmonary Patho, Retains Act. vs. Resis Macrolide & PCN-resistant S. Pneumonia, (ADRs GI Upset & QTc Prolongation) |
| Macrolides (Respiratory)? | Azithromcin, Clarthromycin, Erythromycin, Dirithomycin (Gm(+), Staph, Strep, M.Cat, H. Influ., Neisseria Gonorrhoeae, Atypicals) |
| Macrolide ADRs? | Hearing loss, Dizziness, LFT Abnormalities, N&V, Diarrhea (less w/Azithromycin) |
| Best Macrolide for M. Cat? | (Clar. = Azith.) > Ery |
| Best Macrolide for H. Influenza? | Azithromycin > (Clar. = Ery.) |
| Teracycline Meds (Respiratory)? | Tetracycline (PO), Doxycyline (Vibrmycin, IV & PO) |
| What are Tetracycline used for? | Only Gm(+) S. Pn. & Atypicals |
| Tetracycline ADRs? | GI upset, Tooth Discolor, Photo Sens., Diarrhea |
| TMP/SMX (Bactrim, IV & PO) ? | Respiratory Gm(+) S. Pneumoniea, PCP's |
| TMP/SMX ADRs? | Rash, Marrow Suppression, Diarrhea |
| TMP/SMX (Bactrim) Stregnths? | PO 80/400, II Strenth PO 160/800, Oral Susp. 40/200 per 5 ml, IV 80/400 per 5 ml. |
| Clindamycin (Cleocin, IV & PO) Covers? | "C": Gm(+) & Aaerobics (B. Frag. growing Resis.)**Community Acquired MRSA/E's |
| Clindamycin ADRs? | C. Diff. Diarrhea |
| Clindamycins don't cover? | No MRSA/E, No Enerococcus |
| Metroidazole (Flagyl, IV & PO) covers? | Only Anaerobes (ADRs Disulfiram-like Rxns, Met'l taste, Perf. Neuropahy) |
| Vancomycin (Vacocin, IV & PO) Covers? | Gm(+), NO Gm(-) (Tx. for C. Diff) |
| Vancomycin ADRs? | Redman (IV = Histimine), Ottotox.(high levels), Do Not Use w/Aminoglycocides (NephoTox.: NMT 10 mcg/ml) |
| Aminoglycoide Meds? | Gentamycin, Tobramycin, Amikacin (all IV) |
| Aminoglycocides Cover? | Gm(+/-) NO Anerobes, NO MRSA/E's |
| Aminoglycocides Best Taken? | Once Daily w/Larger Dose |
| Aminoglycocide ADRs? | Nepho & Ototo Tox. |
| Carbopnem Meds? | Imipenem-Cilatatin (Primaxin, IV), Meropenum (Merem, IV), Ertapenem (Invanz, IV) |
| Carbopenems Cover? | Gm(+), Gm(-), Anarobes (NO MRSA/Es, NO Enterococcus) |
| Carbopnem ADRs? | Comp. w/Ceph's for Beta-Lact. Allergies (as high as 25%), Diarrhea, Renal Disfunction = Seizures (1% Imi. & 0.5% Mero.) |
| Aztreonam (Azctam, IV) Covers? | Only Gm(-), Low S.E. (Rash, diarrhae), NO Cross-Reactivity w/PCN Allergies |
| Ceph's MTT Side Chains? | Cefamandole, Cefperzone, Cefmetazole, Cefotetan (MTT's Disulfram-Like & Blood Thinner - Avoid w/Warfrin Use) |
| Ceph's 1st. Generation? | Cefazolin (IV), Cefadroxil (PO), Cephalexin (PO) "SPEcK" |
| Ceph's 2nd. Generation? | Cefuroxime (IV), Cefuroxime Axetil (PO), Cefaclor (PO) "HNM SPEck" |
| B. Frag. SPEck's ? | Cefotetan (IV), Cefoxitin (IV) |
| Ceph's 3rd Generation? | Gm(+/-) No Psuedo.: Cefotaxime, Ceftriaxone, Ceftizoxime (all IV), Cefixime (PO = Poorman's Cefotaxime) |
| Ceftazidime (Fortaz, IV) Covers? | Expand Gm(-), YES Psuedomonas!!! NO Gm(+) but, 3rd. Gen. Ceph. |
| Ceph's 4th Generation? | Cefepime (IV): Good Gm(+/-) Coverage, equal to both Ceftriaxone +Ceftazidime |
| Which Ceph Maintains Activity Against 3rd Gen. Resistant Gm(-) Organisms? | Cefepime (IV) 4th Gen. |
| BLIC Meds? | Amox/Clav (augmentin, PO), Amp./Subactam (Unasyn, IV), Ticar/Clav. (Timentin, IV), Piperacillin/Tazobactam (Zosyn, IV) |
| BLICs Cover? | Staph, B. Frag., M. Cat, E. Coli, Klebsiella, Proteus |
| BLIC ADRs? | Alergy, Renal Disfnc. Seizures, C. Diff. Diarrhea |
| Organisms Producing both Beta-Lactamase & PCNase? | Staph, H. Influ, M. Cat, B. Frag. |
| PCNase-Resistant-PCN Meds? | Nafcillin & Oxacillin (IV); Cloxacillin & Dicloxacilln (PO) ***Gm(+) Only, NO enterococcus, NO MRSA/Es |
| AntiPseudomonal PCN's ? | Ticarcillin & Piperacillin |
| Piperacillin & Ticarcillin Cover? | Gm(+) Strep.(NO Staph), Gm(-) Enterococcus, H. Influ., & Psuedomonas (Piper. > Ticar) |
| Piperacillin can cover what, also? | Tx. Flesh Eating Strept. & Enterococcus |
| AminoPCN Meds? | Ampicillin (Inj/PO), Amoxicillin (PO) |
| AminoPCN (Amp. & Amox.) Cover? | No Staph, Yes: Strept, Entero, E.Coli, Proteus, H. Influ., Mouth Anaerobes Only (No: Staph, Ps., M.Cat, B.Frag) |
| H. Influ. produce Beta-Lactamase ? | > 15 - 65 % |
| M. Cat & B. Frag. Produce Beta-Lactamase ? | > 90 % |
| Enterococcus Gm(+)? | Enterococcus (faecalis, faecium) |
| Enteobacteriacea Gm(-)? | E. Coli, Klebsiella, Enterobacter, Seratia, Proteus, Morganella, Providecia |
| Resp. Bugs? | H. Influenzae & Moraxela Catarhalis |
| Gm(+) Cocci - Clusters? | Staph A/E |
| Gm(+) Cocci - Chains/Pairs? | Strept/Enterococcus |
| Gm(-) Cocci? | Neisseria (Meninititis, Gonorrheae), Moraxella Catarrhalis |
| Gm(-) Rods/Bcilli? | Lactose Fermenting: "FREKLES", Non-Lactose Fermenting (Psuedomonas, Proteus) |
| Healthy Oropharyngeal Flora? | Strept, Corynebacterium, Neisseria, Haemophilus; 2 Gm(+ & -) |
| Tip Culture Colonized? | >15 Colonies = Colonized |
| CSF Culture (Bac Infection)? | Bacteria Infection = WBC/mm 1,000 - 5,000 (PMN & Proteins UP, Glucose is DOWN) |
| CSF Culture (Viral)? | Viral CSF: WBC/mm = 100 - 1,000 (PMN or Lymph. UP, Pro. & Glu. VARRIABLE) |
| UTIs? | Greater than, or Equal to, 10^5 Bac/ml. (Lower fr PTs w/Sx.) 8-10 WBC/mm^3 |
| Aminoglycoside Tx. ? | Combo Tx. ONLY for Aminoglycosides |
| VRE's ? | Vancomcin-Resistant Enterococcus |
Created by:
MCPHS
Popular Pharmacology sets