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Ch. 58 Pharm
Drug for STD's, Womens Health and Infertility
| Question | Answer |
|---|---|
| Women seek gynecologic health care for | Change in menstraul cycle, menstraul or pelvic pain, and changes in vaginal secretions |
| Vulvovaginal Infections | Changes in vaginal secretion, vaginal pruritus, irritation and pain |
| Three common vulvovaginal infections | Vulvovaginal Candidiasis (Yeast Infection), Bacterial vaginosis, and Trichomoniasis |
| Vulvovaginal Candidiasis (Yeast Infection) cause | Inflammation, irritation, burning while urinating, thick curdlike discharge, and pruritus |
| Vulvovaginal Candidiasis (Yeast Infection) treatment | Fluconazole - oral administration |
| Bacterial vaginosis | Normal bacteria in vagina replaced with Gardnerella Vaginalis, trasmitted via sexual contact |
| Bacterial vaginosis causes | Larger amounts of thin white vaginal discharge with a fishy odor |
| Bacterial vaginosis treatment | Metronidazole - tablet or gel administration |
| Trichomoniasis | Caused by Trichomonas vaginalis |
| Trichomoniasis causes | Copious frothy yellow discharge |
| Induction of Ovulation | First line of pharmacologic treatment for infertile women |
| Drugs that enhance induction of ovulation | Clomid and Ovidrel |
| Clomid | Estrogen antagonist that binds with estrogen receptors with hypothalamus |
| Clomid Effects | Allows more GnRh which releases more FSH and LH resulting in increased estrogen levels |
| Ovidrel | Normalize hormone levels with little side effects |
| Ovidrel Effects | Ensures development of corpus luteum after ovulation |
| Sexually Transmitted Infections (STI) | May be localized or spread through reproductive tract increasing the risk of pelvic infection |
| Two types of STI's | Bacterial Pathogens and Viral Pathogens |
| Bacterial Pathogens | Gonorrhoeae, Chlamydia and Syphilis |
| Syphilis | Systemic disease that include active and dormant stages. |
| Syphilis treatment | Benzathine penicillin |
| Viral Pathogens | Herpes simplex 1 and 2, HIV, HPV |
| HPV | Include 80 strands, 12 low risk and 15 high risk |
| High Risk HPV | Can cause cervical cancer in women |
| HPV Prevention | Gardisil |
| Gardisil | Prevents against cervical cancer and protects against strands 6-11 and 16-18. Administer in three seperate injections. |