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Ch. 58 Pharm

Drug for STD's, Womens Health and Infertility

QuestionAnswer
Women seek gynecologic health care for Change in menstraul cycle, menstraul or pelvic pain, and changes in vaginal secretions
Vulvovaginal Infections Changes in vaginal secretion, vaginal pruritus, irritation and pain
Three common vulvovaginal infections Vulvovaginal Candidiasis (Yeast Infection), Bacterial vaginosis, and Trichomoniasis
Vulvovaginal Candidiasis (Yeast Infection) cause Inflammation, irritation, burning while urinating, thick curdlike discharge, and pruritus
Vulvovaginal Candidiasis (Yeast Infection) treatment Fluconazole - oral administration
Bacterial vaginosis Normal bacteria in vagina replaced with Gardnerella Vaginalis, trasmitted via sexual contact
Bacterial vaginosis causes Larger amounts of thin white vaginal discharge with a fishy odor
Bacterial vaginosis treatment Metronidazole - tablet or gel administration
Trichomoniasis Caused by Trichomonas vaginalis
Trichomoniasis causes Copious frothy yellow discharge
Induction of Ovulation First line of pharmacologic treatment for infertile women
Drugs that enhance induction of ovulation Clomid and Ovidrel
Clomid Estrogen antagonist that binds with estrogen receptors with hypothalamus
Clomid Effects Allows more GnRh which releases more FSH and LH resulting in increased estrogen levels
Ovidrel Normalize hormone levels with little side effects
Ovidrel Effects Ensures development of corpus luteum after ovulation
Sexually Transmitted Infections (STI) May be localized or spread through reproductive tract increasing the risk of pelvic infection
Two types of STI's Bacterial Pathogens and Viral Pathogens
Bacterial Pathogens Gonorrhoeae, Chlamydia and Syphilis
Syphilis Systemic disease that include active and dormant stages.
Syphilis treatment Benzathine penicillin
Viral Pathogens Herpes simplex 1 and 2, HIV, HPV
HPV Include 80 strands, 12 low risk and 15 high risk
High Risk HPV Can cause cervical cancer in women
HPV Prevention Gardisil
Gardisil Prevents against cervical cancer and protects against strands 6-11 and 16-18. Administer in three seperate injections.
Created by: cdanella
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