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exam 2

hematology

Termdefinition/description
Reticulocyte Immature RBC, still contain organells, stain grey-blue, <1% of RBC's
nRBC nucleated red blood cell, seen during severe anemia, shows as a nucleated WBC on differential leukocyte ct.
Cobalt ruminants, B-12 molecule, excess causes polycythemia
Polycythemia decrease in RBC
Anisocytosis a medical term meaning that a patient's red blood cells are of unequal size. This is found in anemia and other blood conditions
Polychromasia variation in the hemoglobin content of erythrocytes.
Hypochromasia abnormal decrease in the hemoglobin content of the erythrocytes. Pale color
Poikilocytosis presence in the blood of erythrocytes showing abnormal variation in shape; acanthocyte, echinocyte, leptocyte, spherocyte, schistocyte
acanthocyte A red blood cell characterized by multiple spiny cytoplasmic projections and found in acanthocytosis dogs and liver disease.
echinocyte burr cell, crenated or dehydrated, improper blood smear
Leptocyte An abnormally thin or flattened red blood cell having a central rounded pigmented area, a middle pigmentless zone, and a pigmented edge. Target and folded cells
Spherocyte a small, globular, completely hemoglobinated erythrocyte without the usual central pallor characteristically found in hereditary spherocytosis but also in acquired hemolytic anemia. rigid, destroyed by spleen
Schistocytes RBC fragments, assoc with anemia
Howell Jolly bodies RBC with nuclear remnants, increase in RBC regenerative anemia, depressed spleenic function. These are nuclear remnants, left behind when the nucleus was extruded from the erythroblast. Dark stained belly buttons.
heinz bodies Intraerythrocytic denatured hemoglobin, new methlyene blue, inclusion bodies resulting from oxidative injury to and precipitation of hemoglobin; Heinz bodies (arrows) project from the surface of red blood cells nose/nipple
Agglutination clumping of RBC's, AIHA, Coombs test
Rouleaux rolos, stacks of coin appearance, increase in protein and fibrinogen normal in equines
Polycythemia increase in RBC, may be due to dehydration
MCV Mean corpuscular vol; MCV = PCV * 10 / RBC
Mean corpuscular hemoglobin Mean weight of Hb contained in avg RBC; MCH = Hb * 10/RBC(millions)
Mean corpuscular Hemoglobin Concentration concentration of Hb in avg RBC; color intensity; MCHC = Hb * 100/ PCV %
Hypochromic < Hb is greater then the avg decrease in RBC volume
Anemia regenrative; non-regenerative; pale MM, exercise intolerence; lethargy
Created by: wccvettech
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