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DEH 2300 Module 1

Applied Pharm for the DH

QuestionAnswer
History: Who studied Pharmacology? Greeks, Romans, Chinese,, Muslims and other early cultures
Synthetic organic chemistry was born in? 1828
Who was recognized as the founder of modern pharmacology? Oswald Schmiedeberg
Testing is done with: animals, humans (ethical issues)
Define Pharmacology Pharmacology derived from prefix pharmaco- (“drug” or “medicine”) + suffix -logy (“study of”)
Stedman’s Medical Dictionary definition of drug: “Therapeutic agent; any substance, other than food, used in the prevention, diagnosis, alleviation, treatment or cure of disease”
Others define drug as: chemical substances that affect biologic systems
Knowledge off pharmacology imperative in order for dental professionals to perform important clinical functions such as: • Obtaining health history • Administering drugs in the office • Handling emergency situations • Planning appointments • Choosing self medication • Discussing drugs • Life-long learning
What are some sources of pharmacology information? Books, journals, CD-ROMs, Internet, & Pharmacists
Generic name: Only one name; first letter lowercase ex: lidocaine For dental drugs, generic provide the equivalent therapuetic results at a cost savings
Trade name: More than one name; first letter capitalized ex: Xylocaine, Octocaine
Metric system: Base 10 language of scientific measurement. * Only metric units should be used in prescription writing.* Solid drugs by weight. Liquids by volume.
Apothecary system: Cumbersome, does not convert to base 10. Measurements of weight in sands, grains, scruples, ounces, pounds. Measurements of volume in drams, and ounces. Still used by some older practitioners.
Avoirdupis system: Used in U.S. commerce (food cans, quarts of milk). 16 oz. in 1 lb. 1 oz. = 30ml metric, I cup (8 oz.) = 240ml
Superscription (Patient’s name, address, age, date and the symbol, Rx [Latin for “recipe” or “take thou” ] )
Inscription Name of drug, dose form, and amount
Subscription Directions to the pharmacist
Signature or Transcription Directions to the patient
Heading Name, address, phone number of prescriber on prescription blank; name, address, phone number of patient written in, and date* (*not a legal prescription without date!)
Body The symbol, “Rx”; name and dosage size or concentration (for liquids) of given drug; amount to be dispensed; and directions to the patient.
Closing Prescriber’s signature; DEA number, if required; refill instructions
Federal law divides controlled substances into: 5 schedules according to their abuse potential
Any Rx for controlled substance must have a: DEA number
All Schedule __ through __ drugs require an Rx II through IV
Schedule II specifications: Written in pen or typed, cannot be phoned in; no refills; may require triplicates in some states (triplicates should be locked away)
Schedule III and IV may be phoned in to pharmacist and may be refilled no more than: 5 times in 6 months
DDR Alphabetic by generic drug name Not bias Least expensive Updated every 2 years Dental implications, brief
LCD Alphabetic by generic name Not bias Moderately expensive Updated 1/year; CD 4/year Dental implications, brief
PDR Alphabetic by manufacturer's name; within that list alphabetic by trade name Bias Moderately expensive 1/year; 4 year; CD=4/year Package insert, not often updated, contains selected drugs
F&C Therapeutic class Not bias Most expensive 1/year; 12/year (paper); CD=4/year Has many tables; includes most prescription and OTC drugs
AHFS Alphabetic by pharmacologic class Not bias Expensive 1/year; CD=4 year Detailed coverage; useful to anser specific questions
USP DI Alphabetic by pharmacologic class Not bias Expensive 1/year; 12/year; CD=4/year Extensive list of properties of drugs
a. Before
a.c. Before meals
A.D. Right ear
A.L. Left ear
b.i.d. Twice a day
gtt. Drop
h. Hour
h.s. Bedtime
o.u. Each eye
o.d. Right eye
o.s. Left eye
p.o. By mouth
p.c. After meals
p.r. By rectum
p.r.n. As needed
q.d. Once a day
q.i.d. Four times a day
q.o.d. Every other day
q6h Every six hours
sl Sublingual
Supp. Suppository
t.i.d. Three times a day
u.d. As directed
Created by: nayray
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