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PUD/GERD Drugs
pharmacology exam 4
| Question | Answer |
|---|---|
| What is the H2 receptor antagonists prototype drug? | Zantac |
| How does H2 receptor antagonist Zantac work? | blocks the h2 receptors in the stomach to decrease acid production |
| What are the most common side effects with h2 receptor antagonists? | they are uncommon and mild |
| What are some nursing measures or teaching methods used with h2 receptor antagonists zantac? | no antacids within 1 hour, administer after meals, monitor liver and renal function |
| What are contraindications of h2 receptor antagonists zantac? | hypersensivity to h2 receptors, acute porphyria, OTC not approved in patients under 12 yrs old |
| Are there drug interactions with h2 receptor antagonists? | yes, may reduce absorption of -zole drugs, smoking decreases effectiveness |
| What is the prototype drug for proton pump inhibitors? | prilosec |
| How does prilosec, proton pump inhibitor work? | reduces acid secretion in the stomach, used short term 4-8 weeks for GERD and PUD, takes 2 hours to reach therapy level but lasts for 72 hours |
| What are side effects of prilosec, proton pump inhibitor? | headache, nausea, vomiting and diarrhea |
| What are some nursing measures to consider when administering proton pump inhibitors like prilosec? | administer before breakfast on an empty stomach, may be administered with antacids, do not chew, crush or divide |
| What are some contraindications when using proton pump inhibitors like prilosec? | hypersensitivity to drug, OTC not approved in patients younger than 18 yrs old |
| Are there drug interactions with Prilosec? | yes, diazepam, phenytoin, CNS depressants may cause elevated blood levels, warafin increases bleeding |
| What is the prototype drug for antibiotics when dealing with h. pylori? | Amoxil |
| How does the drug Amoxil work? | inhibits bacterial growth on cell wall synthesis |
| What are the side effects of Amoxil? | GI disturbances, headache |
| What are the nursing considerations when administering Amoxil? | continue antibiotic for full course, space doses evenly, take with food if GI upset occurs, hold meds if rash or diarrhea present |
| What are the contraindications with Amoxil? | hypersensitivity to penicillin, patients with active mono infection |
| Are there drug interactions with Amoxil? | yes, birth control, it may decrease the effectiveness |
| What is a miscellaneous agent for treatment with PUD or GERD? | carafate |
| How does carafate work? | protects damaged mucosa from further destruction by absorbing gastric acid, pepsin and bile salts |
| What are the side effects of carafate? | constipation |
| What are the nursing considerations when administering carafate? | it is taken 4 times a day, administer 1 hour before meals and at bedtime, may be crushed and dissolved in water, avoid antacids within 30 minutes of taking carafate |
| Are there contraindications to carafate? | no |
| What drugs interact with carafate? | antacids |