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PUD/GERD Drugs

pharmacology exam 4

QuestionAnswer
What is the H2 receptor antagonists prototype drug? Zantac
How does H2 receptor antagonist Zantac work? blocks the h2 receptors in the stomach to decrease acid production
What are the most common side effects with h2 receptor antagonists? they are uncommon and mild
What are some nursing measures or teaching methods used with h2 receptor antagonists zantac? no antacids within 1 hour, administer after meals, monitor liver and renal function
What are contraindications of h2 receptor antagonists zantac? hypersensivity to h2 receptors, acute porphyria, OTC not approved in patients under 12 yrs old
Are there drug interactions with h2 receptor antagonists? yes, may reduce absorption of -zole drugs, smoking decreases effectiveness
What is the prototype drug for proton pump inhibitors? prilosec
How does prilosec, proton pump inhibitor work? reduces acid secretion in the stomach, used short term 4-8 weeks for GERD and PUD, takes 2 hours to reach therapy level but lasts for 72 hours
What are side effects of prilosec, proton pump inhibitor? headache, nausea, vomiting and diarrhea
What are some nursing measures to consider when administering proton pump inhibitors like prilosec? administer before breakfast on an empty stomach, may be administered with antacids, do not chew, crush or divide
What are some contraindications when using proton pump inhibitors like prilosec? hypersensitivity to drug, OTC not approved in patients younger than 18 yrs old
Are there drug interactions with Prilosec? yes, diazepam, phenytoin, CNS depressants may cause elevated blood levels, warafin increases bleeding
What is the prototype drug for antibiotics when dealing with h. pylori? Amoxil
How does the drug Amoxil work? inhibits bacterial growth on cell wall synthesis
What are the side effects of Amoxil? GI disturbances, headache
What are the nursing considerations when administering Amoxil? continue antibiotic for full course, space doses evenly, take with food if GI upset occurs, hold meds if rash or diarrhea present
What are the contraindications with Amoxil? hypersensitivity to penicillin, patients with active mono infection
Are there drug interactions with Amoxil? yes, birth control, it may decrease the effectiveness
What is a miscellaneous agent for treatment with PUD or GERD? carafate
How does carafate work? protects damaged mucosa from further destruction by absorbing gastric acid, pepsin and bile salts
What are the side effects of carafate? constipation
What are the nursing considerations when administering carafate? it is taken 4 times a day, administer 1 hour before meals and at bedtime, may be crushed and dissolved in water, avoid antacids within 30 minutes of taking carafate
Are there contraindications to carafate? no
What drugs interact with carafate? antacids
Created by: bkgrota
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