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Random Psych
| Question | Answer |
|---|---|
| Types of Schizophrenia | Paranoid Catatonic Undifferentiated Residual Disorganized |
| Typical antipsychotic MOA | block postsynaptic dopamine-2 receptors (anticholinergic, antihistamine, and alpha-blocking properties) |
| Fluphenazine PO to IM dosing (decanoate) | 1mg PO = 1.25mg IM q2wks |
| Haloperidol PO to IM dosing (decanoate) | 1mg PO = 10mg IM q4wks |
| Abilify MOA | partial agonist of D2 receptor |
| Typical antipsychotics | Crazy (chlorpromazine) Typical (thioridazine) People (perphenazine) Follow (fluphenazine) Hitler (haloperidol) |
| Dystonic reaction treatment | benztropine 1-2mg IM or diphenhydramine 25-50mg IM q30 mins |
| akathisia (def & tx) | restless legs, can't sit still treat with lipophillic BBs (propranolol), BZDs, clinidine, anticholinergics |
| Neuroleptic Malignant Syndrome presentation | rapid (<24hrs) body temp >104 lead-pipe rigidity HTN diaphoresis inc HR incontinence inc. LFT, CPK, WBC |
| dopamine agonist for NMS treatment | bromocriptine (Parlodel) |
| smooth muscle relaxant for NMS treatment | dantrolene (Dantrium) |
| thioridazine BBW | QT prolongation (metabolite is more potent) |
| thioridazine AE not with others | pigmentary retinopathy at doses >800mg/day |
| clozapine monitoring criteria | Weekly WBC w/ diff (D/C if WBC <3,500 or ANC <2,000) 6 months stable = biweekly dosage 12 months stable = q4wks dosage |
| DOPA and prolactin | dopamine is anti-prolactin block DOPA = increase prolactin |
| Smoking and antipsychotics | smoking nicotine binds to alpha7 nicotinic receptor and gives some psychotic relief. Smoking may require increased dose of antipsychotic |
| atypical psychotic with cataract risk | quetiapine (Seroquel) |
| lithium levels | draw 2-8hrs after dose acute=0.6-1.2 mEq/L maintenance=0.8-1.0 mEq/L |
| lithium labs | thyroid (may cause hypothyroidism) SCr&BUN (100% renally eliminated) CBC (may cause leukocytosis and reactivate leukemia) electrolytes (hyponatremia can cause Li toxicity) ECG (flat or invert T waves, reversible) Lithium level pregnancy Category D |
| VPA BBW | hepatotoxicity |
| lithium | Mood stablizer Bipolar maintenance Bipolar acute mania |
| valproic acid (Depakote) | Mood stabilizer&Anticonvulsant Bipolar acute mania Migraine pxs Absence szr simple&complex Partial szr complex |
| carbamazepine () | Anticonvulsant FDA: Epilepsy, Trigeminal Neuralgia, Bipolar NonFDA: |
| DSM-IV dignostic for depression | *At least 5 symptoms mostly every day for 2-wk period *Must represent a change from previous fxning *At least 1 symptom must be depressed mood or anhedonia CAGEPISS |
| DMS-IV for schizophrenia | *2+ symptoms for at least 1 month: hallucinations, delusions, disorganized speech, grossly disorganized or catatonic behavior, negative symptoms, anhedonia, flat affect, avolition *Significant social disturbances continuous and persist for 6 months |
| SSRI for OCD | fluvoxamine (Luvox) |
| TCA for enuresis | imipramine |
| TCA for anxiety | doxepin (Sinequan) |
| TCA for OCD | clomipramine (Anafranil) |
Created by:
psugirl033
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