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Pharmacology
Q | A |
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Young's rule | Age of a child/Age of a child+12X Average adult dose = child's dose |
Clark's rule | Weight of a child in pounds/150 X Average adult dose= Child's dose |
Fried's Rule | Age in mo/150 X average adult dose = Child's dose |
Body surface area | SA(m2)/1.73Xadult dose = Child's dose |
Bronchodilators | Bronchodilators are medicines that help open the bronchial tubes (airways) of the lungs, allowing more air to flow through them. |
What are the example of Bronchodilators | Theodur, Theophylin, Isuprel; albuterol (Proventil, Ventolin), epinephrine (Primatene), ipratropium (Atrovent), metaproterenol (Alupent, Metaprel), and terbutaline (Brethine). |
Pharmacology | The study of drugs and their actions in the living body. |
Absorption | Occurs when the active ingredients of the drug enters the body fluid |
What is liver function | inactivates and metabolizes drug |
pharmacokinetic phase | The pharmacokinetic phase of drug therapy considers whether the drug is getting to the site of action, and how long it is staying there to have an effect. |
3 General route for body to absorb drugs | 1. Enteral 2.Parentenal 3.Parental |
Enteral routes | 1.P.o, 2. Tubal=NGT,GT, 3. Jejunostomy tube C. Suppository,=rectum, vagina,urethra, and 4. Enema. |
Parental route: | 1. IM sa antibiotics, narcotics 2. SQ.sa insulin, flushots & tetanus3. ID sa. TB 4. IV. within the vein. |
Drugs can be excreeted trhu? | Urine, feces, sweat, tears, breast milk or expired air |
Cumulative effect | A drug that build up in the body which can lead to toxic (harmful) or even lethal (deadly) effects. |
CCS Chemotherapeutic drugs | Cytosar(Cytarabine),adrucil(fluopouracil),mexate(Methotrexate),purinethal(B-6 Mercaptopurine) |
corticosteroids | are anti-inflammatory medications often prescribed for asthma and other lung diseases, arthritis, allergies and blood cancer. |
Vincristine | is a vinca alkaloid from the Madagascar periwinkle (Catharanthus roseus, formerly Vinca rosea and hence its name). It is used in cancer chemotherapy. |
L-asparaginase | is an enzyme which is used to treat acute lymphoblastic leukemia (ALL). It is marketed under the brand name ElsparĀ®. It can be given intramuscularly or intravenously. |
Corticosteroid, Vincristine, L-asparaginase | Watch for fluid retention |
What is the S/s of hypersensitivity to any drug, including anti-body: | Petechial rash, slight swelling of any part in the body |
Coumadin | Warfarin (Coumadin) is a blood-thinning medication (anticoagulant) used to treat and prevent blood clots. For most people with a single episode of deep vein thrombosis (DVT), treatment with full-dose blood thinners is usually for only a limited time. |
What does heparin do to the body | inhibits the formation of clots. |
Pentobarbital | Never inject w/ IM, Pentobarbital's FDA approved human uses include treatment of seizures and preoperative (and other) sedation; it is also approved as a short-term hypnotic.[3] |
Pentobarbital | Pentobarbital is used to treat insomnia (for up to 2 weeks) and to induce sleep before surgery. |
Norvasc/amlodipine | Antihypertensive (calcium channel blockers) |
Tenormin (atenolol) | Antihypertensive (beta blocker) |
Capoten | Antihypertensive (ACE inhibitor) |
Vasotec | Antihypertensive |
Lasix (furosemide) | Antihypertensive (loop diuretics) |
Apresoline | Antihypertensive |
Aldomet | Antihypertensive |
Aldoril | Antihypertensive |
Lopressor (metoprolol tartrate) | Antihypertensive |
Minipress | Antihypertensive |
Aldactone | Antihypertensive |
soptin SR | Antihypertensive |
Diuril | Antihypertensive |
HCTZ (Hydrodiuril) | Antihypertensive (diuretic)--thiazid |
Dilantin (phenytoin) | Anticunvulsant |
Depakote | Anticonvulsants |
A combination of drugs is usually used for chemotheraphy to delay the emergence of ------ | resistance |
When drugs are usually used to relieve symptoms, they are said to have ..... effects. | palliative |
Administering dilantin | NGT, GT or peg 1 hour prior or after adm must turn off, PO with hold food 1 hr prior and after adm. |
Syringe that is calibrated in units? | Insulin syringe are calibrated in unit others are in CC's |
TB syringe is calibrated in what size? | in 1 CC which is fr 0.1 - 1 cc |
which area of the body is for IM in adult? | Dorsogulated (buttock area) the most used, Ventrogluteal (iliac), and Deltoid (upper arm) |
Adrenal costicosteroid medicine | Prednisone, decadrone, solu-medrol, aristocort, cortef, cortone, florinef |
Most important side effects of Lasix | Loss of K+ |
Most important side effects of Lanoxin | Brady cardia. If Hr < 60 stop. |
Most important side effects of Coumadin | Bleeding |
Most important side effects of MSO4 or any narcotic? | Respiratory depression |
Most important side effects of streptokinase | Tarry stool |
When codein, morphin and demoral administered and respiration get depressed what do you give? | Narcan ( naloxone ). |
PCA is | A drug delivery system that allow pt. to administer analgesic whenever needed |
What is the requirement for a pt. to use PCA | Pt must be Alert and able to follow simple direction. |
What is Theophylin? ( theodur) | Theophylline is used to prevent and treat wheezing, shortness of breath, and difficulty breathing caused by asthma, chronic bronchitis, emphysema, and other lung diseases. It relaxes and opens air passages in the lungs, making it easier to breathe. |
what happen in def. of vit A | Night blindness |
what happen in def. of vit D? | Rickets in children and osteomalacia in adults which are both related to defects in bone. |
what happen in def. of vit k | a tendency for spontaneous bleeding or in prolonged and excessive bleeding with trauma or injury. |
parentenal route | other than GI route s.a. Needle uises. |
The most common hypoglycemia med is | sulfonilureas |
Allergic reaction, for example, poison ivy are treated with .......theraphy | Corticosteroid |
When mixing insulin whcih one to draw first | draw regular insulin into the syringe first. |
The antidote for bleeding complication during coumarin theraphy is? | Vit K |
The antidote for serious bleeding during heparin theraphy is? | Protamine |
Digitalis is called ----- because of its action to the heart | Cardiotonic |
When MD ordered versed 3 mg IM preoperatively, while on hand are vials labeled 5 mg/ml. What does it mean? | = D/H X Q =3/5 X 1= 0.6 ml |