click below
click below
Normal Size Small Size show me how
Pharm cardio
Cardiac drugs Scott
| Question | Answer |
|---|---|
| Drugs that affect the CVS | Cardiac Glycosides Antihypertensive Anticoagulant |
| Cardiac Glycosides | effects the tuning of the heart help control the ventricular response to atrial fibbrillation |
| Anithypertensive Drugs | effect blood pressure |
| Anticoagulant Drugs | Blood thinning |
| Cardiac Glycosides Action on contractions | Increase force of myocardial contractions and then slows rates |
| Cardiac Glycoside Action on heart size | Decreases |
| Cardiac Glycoside action on cardiac output | Increases Cardiac Output |
| What are cardiac gylcosides used in treatment of? | Atrial fibrillation and congested heart failure |
| Name two types of cardiac glycosides | Digoxin (Lanoxin) Digotoxin (Crystogdigin) |
| Digoxin onset is ______? Digotoxin onset is _______? | Digoxin - slow onset, slow elimination Digotoxin - Rapid onset, short duration |
| Digitalizing Dose | Stronger initial dose |
| Maintenance Dose | Lowered does to stay on for life |
| Toxic effects of Cardiac Glycosides | HA, fatigue, seizures, dysrhythmia, colored vision, anorexia, nausea, vomitting and diarhea |
| Therpeutic window of cardiac glycosides | Narrow. very small amount that can be toxic from pt to pt |
| Nursing Implications for cardiac glycosides - when to notify physician | Pulse <60 or >120 check pulse rate before giving weight gain of more than 2lbs per day |
| Nursing Implications for cardiac glycosides | Antacids or milk products 2 hours before or after med Eat foods high in K+ Take at the same time everyday Anorexia is an early sign of toxicity Do not withdraw abrubtly |
| Antihypertensive Vasodilators | Nitroglycerin |
| Nitroglycerin Actions | treatment of prevention of Angina pain dilates collateral cardiac vessels redistribution of blood flow to ischemic ares in endocardium |
| Nitroblycerin methods of Administration | Sublingual Transdermal Patch Aerosol - under tongue |
| Prophylactic use of Nitroglycerin | Topical ointment or trans dermal patch. Tolerance may occur, so take off at night and back on in the morning Oral route |
| Acute use of Nitroglycerin | Sublingual, Aerosol, IV |
| Sublingual Nitroglycerin | Place under tongue, let dissolve, then swallow |
| Sublingual Nitroglycerin starts to take action when? | 1-3 minutes |
| Sublingual Nitroglycerin - How many patients have releif? | 90% |
| Sublingual Nitroglycerin Maximum dose | 3 in 15 minutes |
| Sublingual Nitroglycerin - what may occur with taking this medicine? | HA and hypertension slowly change positions |
| How long is a sublingual tab good for? How to store container? | 3 months Avoid heat, light and moisture |
| How to tell if sublingual nitro tab is still potent? | It will sting when placed under the tongue |
| Is a sublingual nitro tab safe to take before a stressful event? | Yes |
| Antihypertensive drugs | Diuretics, ACE inhibitors, Calcium Channel Blockers, Beta Blockers |
| Becuase subgroups of Diuretics exist, what must be known about a particular diuretic? | The mechanism of action |
| What does a diuretic do? | Decreases plasma and extracellular fluid volume |
| Will the amount of urine produced by the kidney increase of decrease with a diuretic? | Increase because diuretic relieves excess sodium and water retention |
| Does a diuretic increase or decrease preload, cardiac output, and total peripheral resistance? | Decrease, thus reducing the workload of the heart |
| Give an example of a diuretic | Lasix |
| Nursing Implications for pt's on diuretics | Daily weight to monitor water/sodium retention 2-3 Liters of fluid a day Take early in the morning High K+ diet (citrus fruit, dried fruit, banana, nuts) |
| When do you contact a doctor when a pt is on a diuretic? | Dizziness, muscle cramps or weakness presents |
| ACE inhibitor actions | Block the conversion of angiotension I to angiotension II (a vasoconstrictor) Reduces the release of aldosterone from adrenal cortex Contributes to loss of sodium and water Reduces BP |
| What does ACE stand for? | Angiotensin-converting Enzyme |
| Give an example of an ACE inhibitor? | Lisinopril |
| How do the actions of an ACE inhibitor treat heart failure? | They prevent sodium and water reabsorbtion, which decrease blood volume and blood return to the heart. This decrease the preload and work required of the heart. |
| What does a Beta Blocker do? | Lowers B/P by blocking the effects of catecholamine's on the beta 1 receptors in the heart Reduces contractibility and CO Slows heart rate |
| How do Beta Blockers work? | They reduce or block the sns stimulation to the heart and the heart's conduction. |
| What are the results of taking a Beta Blocker? | reduced heart rate delayed AV node connection reduced myocardial contractility decreased myocardial automaticity |
| Give an example of a Beta Blocker | Carvedilol (Coreg) |
| Calcium Channel Blockers | Decrease the force of smooth muscle contractions results in lower b/p and peripheral resistance |
| What may initially happen when taking an antihypertensive drug? | dizziness |
| What meds should an pt on antihypertensive drugs avoid? | OTC that cause vasoconstriction |
| Should you abruptly withdraw from an antihypertensive med? | NO |
| Avoid what kinds of food when on antihypertensive meds? | foods high in sodium |
| What electrolyte needs to be increased when on a hypertensive med? | K+ |
| What do anti-coagulants do? | inhibit the action or formation of clots |
| What are the actions of Heparin | Interferes with conversion of prothrombin to thrombin Prevents conversion of fibrinogen to fibrin |
| How can Heparin be given? | Sub Q or IV |
| What is the half life of Heparin? | 1-2 hours |
| What should you not do when and after administering Heparin? | Do not aspirate or massage into abdomen |
| What two lab tests are needed to determine if therapeutic level of Heparin is reached? | Activated partial prothrombin time (aPTT) Activated clotting time (ACT) |
| What is the antidote to Heparin? | Protamine Sulfate |
| What is the action of Coumadin? | Interfere's with clotting by interfering with Vit K dependant clotting factors |
| Is Coumadin given orally or IV? | Orally |
| What is the half life and duration of Coumadin? | 0.5-3 days half life 2-5 days duration |
| What are the lab tests associated with Coumadin? | Protime (P.T.) International Normalized Ratio (INR) |
| What is the antidote for Coumadin? | Vitamin K |
| What are the nursing implications for pts on anti-coagulants? | monitor labs closely check labels of OTC drugs shave only with electric razor avoid rough sports any bleeding lasting longer than 10 minutes with pressure is a concern brush teeth with soft bristles avoid foodwith Vit K (fish, banana's, leafy vegs,t |
| Antiplatelet Agents actions | prevent platelet plugs from forming beneficial in defending body against MI or strok |
| Give an example of an antiplatelet agent? | ASA - aspirin |
| What are the actions of a thrombolytic drug? | anticoagulant that breaks down or lyse preformed clots in vessels streptokinase (an enzyme that can break down a formed clot) |