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Skills Final Exam
Brand and generic
| generic | brand | Class | MOA |
|---|---|---|---|
| Amoxicillin Trihydrate | Amoxil | Aminopenicillian designed for Gram (-) | Inhibition of cell wall synthesis (peptidoglycan) synthesis via inhibition of transpeptidase via ester linkage (D-alanyl-D-alanine) |
| Amoxicillin Trihydrnate/Claulanate potassium | Augmentin | Aminopenicillin, designed for Gram (-), also anaerobic and has Beta lactamase inhibior | Inhibition of cell wall synthesis (peptidoglycan) synthesis via inhibition of transpeptidase via ester linkage (D-alanyl-D-alanine) |
| Ampicillin | Principen | Aminopenicillin designed for Gram (-) | Inhibition of cell wall synthesis (peptidoglycan) synthesis via inhibition of transpeptidase via ester linkage (D-alanyl-D-alanine) |
| Ampicillin/sulbactam | Unasyn | Aminopenicillin, designed for Gram (-),have anaerobic, Gram (+), and Beta lactamase inhibior | Inhibition of cell wall synthesis (peptidoglycan) synthesis via inhibition of transpeptidase via ester linkage (D-alanyl-D-alanine) |
| Azithromycin Dihydrate | Zithromax | Macrolide, Gram + (not MRSA), Gram (-), excellent atypical | Reversibly bind the 50s ribosomal subunit and inhibit translation. |
| Cephalexin | Keflex | First generation Cephlosporin, Gram (+) | Inhibition of cell wall synthesis (peptidoglycan) synthesis via inhibition of transpeptidase via ester linkage (D-alanyl-D-alanine) |
| Cefazolin | Ancef | First Generation Cephalosporin, Gram (+) | Inhibition of cell wall synthesis (peptidoglycan) synthesis via inhibition of transpeptidase via ester linkage (D-alanyl-D-alanine) |
| Cefepime | Maxipime | Forth generation cephalosporin, Excellent gram (-) pseudomonas, and gram (+) | Inhibition of cell wall synthesis (peptidoglycan) synthesis via inhibition of transpeptidase via ester linkage (D-alanyl-D-alanine) |
| Cefprozil | Cefzil | Second generation cephalosporin, Gram + and Gram (-) | Inhibition of cell wall synthesis (peptidoglycan) synthesis via inhibition of transpeptidase via ester linkage (D-alanyl-D-alanine) |
| Ceftazidine | Fortaz | Forth generation cephalosporin, Excellent Gram (-). Pseudomonas activity! | Inhibition of cell wall synthesis (peptidoglycan) synthesis via inhibition of transpeptidase via ester linkage (D-alanyl-D-alanine) |
| Ceftidoren | Spectracef | Third generation cephalosporin,(PO) Gram (-) excellent | Inhibition of cell wall synthesis (peptidoglycan) synthesis via inhibition of transpeptidase via ester linkage (D-alanyl-D-alanine) |
| Ceftriaxone | Rocephin | Third generation cephalospoin, (IV)Gram (-) but this is the gold standard for Staph and Strep infections. Hepatic clearance | Inhibition of cell wall synthesis (peptidoglycan) synthesis via inhibition of transpeptidase via ester linkage (D-alanyl-D-alanine) |
| Cefuroxime Axetil | Ceftin | Second generation cephalosporin, (PO) Gram (+)> gram (-). | Inhibition of cell wall synthesis (peptidoglycan) synthesis via inhibition of transpeptidase via ester linkage (D-alanyl-D-alanine) |
| Ciprofloxacin | Cipro | Fluoroquinolone, (IV and PO), Gram (-) excellent, Gram (+), atypical | Inhibition of Topo II (gram-)DNA gyrase preventingunwinding of DNA and Topo IV (gram +) segration of daughter chromosomes. |
| Clarithromycin | Biaxin | Macrolide, Gram (+) not MRSA, Gram (-) and excellent atypical | Binds to the 50s ribosomal subunit to inhibit translation. |
| Daptomycin | Cubicin | Cyclic lipopeptide, Gram (+) | Calcium dependant insertion into lipid tail and depolarizes cell membrane (punch hole) |
| Doxycycline Hyclate | Vibramycin, Vibra-tabs | Tetracycline, Gram (+)MRSA , Gram (-), rickesseta, yersina, tuleremia | Bind the 30s ribosome and block aminoacyl-tRNA thus elongation is inhibited. |
| Ertapenem | Invanz | Carbapenems, Have broadest spectrum of activity. Excellent Overall: Gram(+), Gram(-)imipenem & meropenem better, anaerobic | Inhibition of cell wall synthesis (peptidoglycan) synthesis via inhibition of transpeptidase via ester linkage (D-alanyl-D-alanine) |
| Gatifloxacin | Tequin | Discontinued Fluoroquinolone, Gram (-)no pseudomonias, Gram (+)no MRSA, atypical Caused glucose abnormalities | Inhibits Topo II (gram -) which uncoils the DNA and Topo IV (gram +) which helps seperate into sister chromosomes |
| Imipenem/cilastatin | Primaxin | Carbapenem, Broadest spectrum class. Gram (+) no MRSA, Gram (-) pseudomonas, anaerobic. Watch CNS-seizure via GABA-ergic | Inhibition of cell wall synthesis (peptidoglycan) synthesis via inhibition of transpeptidase via ester linkage (D-alanyl-D-alanine) |
| Levofloxacin | Levaquin | Fluoroquinolone, Excellent Gram (-)pseudomonas, Gram (+) not MRSA, and Atypical | Inhibits Topo II (gram -) which prevents uncoiling of DNA and Topo IV (Gram +) which prevents sister chromosomes from forming. |
| Linezolid | Zyvox | Oxazolidinones, (IV and PO) Excellent Gram (+) MRSA, atypical (TB) | Binds the 50s and 30s ribosomal subunit preventing the 70s subunit to form inhibiting protein synthesis. |
| Meropenem | Merrem | Carbapenem antibiotic, Greatest spectrum of activity. Gram (+) not MRSA, Gram (+) pseudomonas, anaerobic | Inhibit peptidoglycan synthesis via transpeptidase inhibition preventing cross linking of peptides in cell wall. |
| Metronidazole | Flagyl | Anaerobic Gram (+)clostridium diff. and Gram (-) | Reductive activation of nitro-group by pyruvate(ferridoxin oxidoreductase) to form ROS which kills bacteria. |
| Minocycline HCl | Minocin | Tetracycline, Gram (+) MRSA, Gram (-), rickettsa, yersina, tulremia | Bind the 30s ribosome and block aminoacyl-tRNA thus elongation is inhibited. |
| Moxifloxacin | Avelox | Fluoroquinolone, Gram (+),Gram (-), atypical, excellent including pseudomonas. The only one with anaerobic activity. | Binds to Topo II (gram -) preventing uncoiling of DNA and Topo IV (gram +) preventing formation of sister chromosomes. |
| mupirocin-ointment or nasal | Bactroban | Topical antibiotic (Impetigo) : Gram + including MRSA | Inhibits bacterial protein synthesis by reversibly and specifically binding to bacterial isoleucyl transfer-RNA synthetase. |
| Nafcillin | Nafcil | Penicillnase resistant PCN. Designed to over come B-lactamase resistance. They are Gram (+) MSSA | Inhibition of cell wall synthesis (peptidoglycan) synthesis via inhibition of transpeptidase via ester linkage (D-alanyl-D-alanine) |
| Nitrofurantoin | Macrobid (macrocrystalline/monohydrate= slower absorption), Macrodantin (macrocrystal) | Nitro moiety= Gram (+) Strep A, B, pneumonia, MSSA, VRE, Gram (-) n.gonorrheae, KEEP, low resistance | Bacteria reduce to reactive metabolite which then inhibit TCA cycle & DNA synthesis of bacteria |
| Penicliin G (IV) | Pfizerpen | Natural PCN- Mainly Gram (+) streptococci, and good on Gram(-) neisseria, and anerobes | Inhibition of cell wall synthesis (peptidoglycan) synthesis via inhibition of transpeptidase via ester linkage (D-alanyl-D-alanine) |
| Penicillin V | Veetids | Natural PCN: Mainly Gram (+) streptococci, and Ok on Gram(-), and anerobes. Used in dental procedures (bacteroides fragillis) | Inhibition of cell wall synthesis (peptidoglycan) synthesis via inhibition of transpeptidase via ester linkage (D-alanyl-D-alanine) |
| Piperacillin/tazobactam | Zosyn | Extended spectrum PCN- Uredopenicillins. Gram (+)no MRSA, Gram (-) pseudomonas and anaerobic. Have beta lactamase inhibitor tazobactam | Inhibition of cell wall synthesis (peptidoglycan) synthesis via inhibition of transpeptidase via ester linkage (D-alanyl-D-alanine) |
| Quinupristin/Dalfopristin | Synercid | Streptogramin, Narrow spectrum: Gram (+) MRSA, VRE | Acts at ribosome 50s interfering with peptidyl transferase inhibition elongation |
| Sulfamethoxazole/Trimethoprim | Bactrium | Sulfaabtibiotic- Broad spectrum: Gram (+ and - ), Atypical , Fungi, and Plasmodium (malaria) | Structural analog of PABA they binds to dihydropteroate synthase which is the first step in dihydrofolic acid synthesis preventing cell wall synthesis. |
| Vancomycin | Vancocin | Gram (+) MRSA- ZERO Gram (-) large molecule cannot penetrate outer membrane. | Binds D-alanyl D alanine terminus of cell wall precursor preventing peptidoglycan synthesis |
| Desogestrel and Ethinyl Estradiol | Mircette | Oral contraception: | Desogestrol a progestin inhibits ovulation via negative feedback of the hypothalamis leadig to less GnRH released thus inhibiting the surge of FSH and LH that normally triggers ovulation. |
| Levonorgestrel and Ethinyl Estradiol | Alesse or Triphasil | Oral contraception | Levonorgestrol a progestin inhibits ovulation via negative feedback of the hypothalamis leadig to less GnRH released thus inhibiting the surge of FSH and LH that normally triggers ovulation. |
| Norethindrone and Ethinyl Estradiol | Ortho-Novum | Oral contraceptive | Norethindrone a progestin inhibits ovulation via negative feedback of the hypothalamis leadig to less GnRH released thus inhibiting the surge of FSH and LH that normally triggers ovulation. |
| Norgestimate and Ethinyl Estradiol | Ortho-Cyclen | Oral contraception | a progestin inhibits ovulation via negative feedback of the hypothalamis leadig to less GnRH released thus inhibiting the surge of FSH and LH that normally triggers ovulation. |
| Conjugated Estrogen | Premarin | Equine estrogens | Acts to increase hormone levels ( menopausal ovaries release no estrogen & progestin) this inhibits pitutary secretion of LH and FSH. |
| Conjugated Estrogens and Medroxyprogesterone acetate | Prempro | Equine estrogen + protestogen | Acts to increase hormone levels ( menopausal ovaries release no estrogen & progestin) this inhibits pitutary secretion of LH and FSH. The progestogen prevents endometrial hyperplasia. |
| Estradiol tablet, cream & Patch | Estrace(tablet & cream), Climara (weekly-patch), Vagifem(vaginal-tablet) , Vivelle (biweek-patch). Estring (vaginal-ring) Femring (vaginal-ring) | Etrogen replacement | Acts to increase hormone levels ( menopausal ovaries release no estrogen & progestin) this inhibits pitutary secretion of LH and FSH. |
| Esterified Estrogens and Methyltesterone | Estratest | Estrogen & androgen replacement | Acts to increase hormone levels ( menopausal ovaries release no estrogen & progestin) this inhibits pitutary secretion of LH and FSH. The androgen (progestrone) prevents endrometrial hyperplasia. |
| Medroxyprogesterone Acetate | Provera | Progestin-Androgen | Acts to increase hormone levels ( menopausal ovaries release no estrogen & progestin) this inhibits pitutary secretion of LH and FSH. And promotes growth of mammary tissues. |
| Alendronate | Fosamax | Anti-resorptive agent | Inhibits bone reabsorption via binding osteoclast and killing. |
| Calcitonin-salmon | Micalcin-nasal 200IU- 1 spray a day | Anti-resorptive (Refrigation) | Similar to human calcitonin, thus it directly inhibits the osteoclast bone reabsorption. Increases the secretion of calcium, phosphate, sodium. |
| Ibandronate | Boniva | Anti-resorptive agent | Inhibits bone reabsorption via binding osteoclasts killing the cell. |
| Raloxifene HCL | Evista | Selective Estrogen Receptor Modulator (SERM) mixed agonist-antagonist | It blocks estrogen receptor and is an agonist to prevent bone loss and improve lipid profile (LDL). |
| Risedronate | Actonel | Anti resorptive | Binds the osteoclast killing the cell preventing bone reabsoption. |
| Doxazosin Mesylate | Cardura | Alpha 1 antagonist- BP effects QD dosing | Binds alpha 1 receptor resulting in vasodialation, of veins and arterioles decreasing PVR. Also relaxes smooth muscle tone of the bladder neck improving urine flow. |
| Tamsulosin HCL | Flomax | Alpha 1A antagonist- (QD dosing) No BP effects | Relaxes smooth muscle tone on the prostrate improving urine flow and decrease BPH symptoms. |
| Terazosin HCL | Hytrin | Alpha 1 antagonist - BP effects | Binds apha 1 receptor to dilate veins & arterioles decreasing PVR and relaxes smooth muscle tone of the bladder neck to improve urine flow. |
| Dutasteride | Avodart | 5 Alpha reductase inhibitor. Pregnant women should avoid pills, patient cannot donate blood for 6 months post D/C of medication. | Inhibition of the conversion of testosterone to dihydrotestosterone a more potent androgen. This prevents the prostrate enlargement. |
| Finasteride | Proscar | 5 alpha reductase inhibitor. Pregnant women should not handle medication. Patient cannot donate blood 6 months post D/C of medication. | Inhibition of the conversion of testosterone to dihydrotestosterone a more potent androgen. This prevents the prostrate enlargement. |
| Sidenadil citrate | Viagra | PDE-5 inhibitor | Increase in NO via inhibiting the degradation of cyclic guanosine monophosphate (degrades NO) leading to smooth muscle relaxation and inflow if blood into the corpus cavernosum. |
| Dicyclomine HCL | Bentyl | Anti-muscaranic agent | Antispasmotic agent, works blockade of the M1 receptor to prolong gastric emptying. Decrease gastric spasms aka IBS diarrhea. |
| Oxybutynin Chloride | Ditropan, this is the immediate release given BID-TID | Anticholinergic-muscaranic for overactive bladder. | Decrease detrussor contraction and increase bladder capacity via M1 receptor. |
| Tolterodine tartrate | Detrol, 1-2mg BID | Anti-cholinergic-muscaranic-For Over active bladder. Non-Selective for M1, M3 | Inhibits bladder contraction and promotes bladder relaxation (filling) by inhibiting the M1 & M3 receptor. |
| Clomtrimazole and betamethasone dipropionate | Lotrisone | Topical Antifungal + steroid | Clotriamazole an imidazole antifungal agent, inhibit 14-α-demethylation of lanosterol in fungi by binding to one of the cytochrome P-450 enzymes. This leads to the accumulation of 14-α- methylsterols and reduced concentrations of ergosterol |
| Mometasone furoate | Elcon-topical or Nasonex-nasal | Topical steroid | May depress the formation,release of mediators of inflamation (kinins, HIS, PG) and inhibits margination & cell migration to area of injury. |
| Acyclovir | Zovirax- oral(200-800mg) , topical, IV | Antiviral | Inhibits viral DNA synthesis and replication by competing with deoxyguanosine triphosphate. |
| Ganciclovir | Cytovene-capsule, implant, IV | Antiviral-CMV retinitis (1000mg TID) | It is phosphorylated to a substance that s binds to deoxyguanosine triphosphate & DNA polymerase resulting in inhibition of viral DNA synthesis. |
| Oseltamavir | Tamiflu | Antiviral agent, neuraminidase inhibitor | A prodrug, it is hydrolyzed and inibits viral neuraminidase altering particle aggregation and release. |
| Rimantadine | Flumadine | Antiviral agent (Amandidine-Symmetrel) | Inhibits the uncoating process of virus. |
| Valgancyclovir | Valcyte-tablet 450mg BID | Antiviral- CMV retinitis | Converted to ganciclovir in the body, it is phosphorylated which competes with the binding of deoxyguanosine triphosphate/DNA polymerase results in inhibition of viral DNA synthesis. |
| Valacyclovir | Valtrex | Antivital- herpes zoster, HSV1 and HSV2 | Converted to acyclovir monophosphate then triphosphate and inhibits DNA synthesis by competing with deoxyguanosine triphosphate for viral DNA polymerase and incorporated into viral DNA. |
| Ampotercin B | Amphocin (conventional) | Polyene-Anti-fungal | Binds to ergosterol altering cell membrane permeability in susceptible fungi and causing leakage of cell components. |
| Ampotercin B liposomal | AmBisome | Polyene- Anti-fungal agent | Binds to ergosterol altering cell membrane permeability in susceptible fungi causing leakage of cell components. |
| Amphotericin B lipid complex | Abelcet | Polyene-Anti-fungal | Binds to ergosterol altering cell membrane permeability in susceptible fungi causing cell membrane leakage. |
| Caspofungin | Cancidas | Echinocandin-Anti-fungal | Inhibits the synthesis of beta 1,3-D-glucan an essential component of the cell wall of susceptible fungi. Mammal's do no have this! |
| Clotrimazole | Gyne-Lotrium (OTC), Lotrium AF (OTC), Mycelex Troche | Azole-Anti-fungal agent | Inhibits 1, 4-α-demethylation of lanosterol in fungi by binding to one of the cytochrome P-450 enzymes. This leads to the accumulation of 14-α- methylsterols and reduced concentrations of ergosterol |
| Fluconazole | Diflucan-oral | Anti-fungal | inhibit 1, 4-α-demethylation of lanosterol in fungi by binding to one of the cytochrome P-450 enzymes. This leads to the accumulation of 14-α- methylsterols and reduced concentrations of ergosterol |
| Griseofluvin | Grifulvin 5 | ||
| Ketoconazole | Nizoral | Anti-fungal | Inhibits 14-α-demethylation of lanosterol in fungi by binding to one of the cytochrome P-450 enzymes. This leads to the accumulation of 14-α- methylsterols and reduced concentrations of ergosterol |
| Nystatin | Mycostain | Polyene- Anti-fungal | Binds to ergosterol in fungal cell membrane changing the cell wall permeability leading to leakage of intracellular components. |
| Voriconazole | Vfend (IV and PO) | Azole- anti-fungal agent | Inhibits 1,4-α-demethylation of lanosterol in fungi by binding to one of the cytochrome P-450 enzymes. This leads to the accumulation of 14-α- methylsterols and reduced concentrations of ergosterol |
| Metformin | Glucophage | Biguanide-oral antidiabetic | Inhibits hepatic glucose production, decreases intestinal absorption of glucose, improves insulin sensitivity, & uptake into the cell. |
| Glipizide | Glucotrol | Sulfonylurea, anti diabetic | Stimulates the insulin release from the beta cells of the pancrease |
| Glipizide and Metformin | Metaglip | Oral anti-diabetic combination | Glipizide will stimulate the beta cells to release insulin and metformin will decrease the production of glucose from liver and improve glucose uptake into the cell. |
| Glimepiride | Amaryl | Sulfonyurea antidiabetic agent | It stimulates the beta cells to release insulin. |
| Glyburide | Micronase | Sulfonylureas antidiabetic agents | It stimulates the beta cells to release insulin. |
| Glyburide and metformin | Glucovance | Sulfonylureas antidiabetic agents | It stimulates the beta cells to release insulin. |
| Pioglitazone | Actos | Thiazolidinesdiones antidiabetic agent | Peroxisome proliferators-activated receptor-gamma (PPARy) which influences glucose and lipid metabolism- Increase in GLUT4 to increase glucose uptake and suppress hepatic and lipolysis. AKA-insulin sensitizer! |
| Rosiglitazone | Avandia | TZD | Peroxisome proliferators-activated receptor-gamma (PPARy) which influences glucose and lipid metabolism- Increase in GLUT4 to increase glucose uptake and suppress hepatic and lipolysis. AKA-insulin sensitizer! |
| Rosiglitazone and metformin | Avandamet | ||
| Insulin Lispro | Humalog | Rapid acting insulin | Mimic endegenous insulin |
| Insulin Aspart | Novolog | Rapid Acting insulin | Mimics endogenous insulin |
| Insulin Regular | Humulin R or Novolin R | Regular Insulin | Onset is 30 minutes and lasts from 3-7 hours. |
| Insulin NPH | Humin N or Novolin N | Mixture of regular insulin and NPH (neutral protamine hagedorn) insulin | Mimic insulin and has NPH which delays effect. |
| Insulin glargine | Lantus | Long acting insulin- mimic basal insulin | Mimics endogenous insulin. Forms a precipitates at physiological pH. The depot slowly releases insulin over 24 hours. Do not mix with rapid acting agents. |
| Insulin detemit | Levemir | Long acting insulin- | Forms a liquid depot that binds albumin and is slowly released. Should not be mixed with rapid acting insulins. |
| exenitide | Byetta | An Incretin mimetic. GLP1 (Incretin) mimetic from the Glia monster | GLP1 increase glucose dependant insulin secretion from the B-cells and suppress glucagons secretion |
| Pramlintide | Symlin | Amlyin agonist | Amylin is a peptide hormone that is co-secreted with insulin. It inhibits post-prandial rise in glucagons & delay gastric emptying & satiey agent. |
| hydrocodone/APAP | Vicodin, Norco, Lorcet HD | Narcotic agonist- CS III | Bind the mu receptor to mimic endogenous opioids |
| atorvastatin | Lipitor | Dyslipidemia agent | It ihibits 5 HMG CoA the rate limiting step of cholesterol synthesis. |
| lisinopril | Prinvil | ACE inhibitor | Competive inhibitor of conversion of angiotension I to II conversion. Result, decreased production of :renin, aldosterone and dialtion of afferent arteriole |
| atenolol | Tenormin | Antihypertensive- Selective B1 Blocker | Block B1 receptor on myocardium & kidney |
| azithromycin | Zithromax | Macrolide antibiotic | Bind 50s ribosome to inhibit elongation thus translation Gram (+ ): Staph & Strep (not MRSA) Gram ( - ): Moderate N.gonorrhoeae, M.catarrhalis, H. influenzae Atypical: DOC for legionella, chlamyda, Mycoplasma |
| furosemide | Lasix | Loop diuretic | Inhibits the Na/K/CL cotransporter on the ascending loop of henle |
| alprazolam | Xanax | Benzodiaziapine (BID) | Bind GABAa and g2 subunit opening Cl channel-hyperpolarization which stabilizes the membrance and reduces neural excitability. |
| metoprolol XL | Toprol XL | Antihypertensive Beta-1 Selective Blocker | Binds beta 1 receptors on the myocardium and kidney. |
| albuterol | ProAir, Proventil | Beta 2 agonist | Bind beta2 receptors in bronchial passage to relax smooth muscle. |
| amlodipine | Norvasc | Antihypertensive- Dihydropyridine calcium channel blocker | Inhibits the calcium voltage gates channels in the myocardium (coronary vasodialation) and vasular smooth muscle (more in DHP) |
| levothyroxine | Levoxyl, Synthroid | Thyroid hormone | Mimics T3 in the body |
| sertaline | Zoloft | SSRI antidepressant | Inhibit the reuptake of presynaptic 5HT. MAO-contra,Caution triptains, phenothiazines |
| escitalopram | Lexapro | SSRI antidepressant | Inhibits the reuptake of presynaptic 5HT. This has very few drug interactions. |
| cephalexin | Keflex | First generation cephalosporin Gram( +) Beta lactamase: Streptococci, staphylocci, cellulitis | Inhibition of cell wall synthesis (peptidoglycan) synthesis via inhibition of transpeptidase |
| zolipidem | Ambien | Non BZD | Binds to adjacent GABAa and prolong chloride into cell promoting membrane stabilization. |
| esomeprazole | Nexium | Proton Pump Inhibitor | Irreversible inhibition of H/K ATPase on the parietal cells |
| triamterene/HCTZ | Dyazide, Maxzide | Aldosterone antagonist and thiazide diuretic | At the distal and collecting duct amiloride & triamterene act directly on area to disrupt Na/K exchange, increasing loss of bicarbonate. And HCTZ- at the distal tubule inhibits Na/CL- symporter. |
| propoxyphene N/APAP | Darvocet-N | Narcotic CS IV | Weakly binding agonist to the opioid receptor on the ascending pain pathway. |
| simvastatin | Zocor | HMG-COA inhibitor, Statin | Inhibits HMG CoA which is the rate limiting step of cholesterol synthesis. |
| montelukast | Singular | Leukotriene receptor antagonist | Inhibits the leukotriene receptor to improve smooth muscle relaxation, decrease inflammation. |
| lasnoprazole | Prevacid | Proton pump inhibitor | Irreversible inhibitor of the H+/K+ ATPase on the parietal cells. |
| metoprolol tartarate | Lopressor | Selective Beta-1 Blocker | Inhibits Beta 1 receptor on myocardium and kidney to decrease BP and HR |
| fluoxetine | Prozac | SSRI | Inhibits the reuptake of 5HT. More of an activating SSRI, it also has the longest half life. |
| lorazepam | Ativan | BZD | Binds the GABA a receptor to increase chloride and promote membrane stabilization. Intermediate half life of about 10 hours. It is metabolized outside of the liver. |
| clopidogrel | Plavix | Antiplatelet agent | Inhibits adenosine diphosphate (ADP)receptor preventing fibrogen binding reducing platelet adhesion and aggregation. |
| oxycodone/APAP | Percocet, Rixicet, Tyelox | Narcotic CS II | Acts as an opioid receptor agonist to inhibit ascending pain. |
| amoxicillin/clavulanate | Augmentin | Aminopenicillins: Designed for Gram (-) excellent with - H. Influenza, Gram (+), anaerobic. Have beta-lactamase inhibitor clavulanate,sulbactam. | Inhibition of cell wall synthesis (peptidoglycan) synthesis via inhibition of transpeptidase via ester linkage (D-alanyl-D-alanine) |
| salmeterol/fluticasone | Advair Diskus | Long acting Beta 2 agonist with steroid- Moderate persistant (symptoms daily or night/week) | Relax bronchial smooth muscle and steroid to prevent inflammation |
| alendronate | Fosamax | Anti-reabsorptive, Bisphosphonate | They bind the osteoclast and kill preventing bone reabsorption. |
| venlafaxine | Effexor XR | SNRI, depression, GAD, SAD, peripheral neuropathy, vasomotor hot flashes | Norephinephrine reuptake inhibitor and weakly 5HT and DA |
| warfarin | Coumadin | Anticoagulant, Coumarin derivative | Inhibits the hepatic synthesis of Vitamin K dependent coagulation factors II, VII, IX, X |
| paroxetine | Paxil | SSRI, antidepressant, OCD, GAD, SAD, PTSD, vasomotor symptoms | A selective 5HT inhibitor. Considered more sedating of the SSRI. SSRI are given QD |
| clonazepam | Klonipin | BZD, treats GAD, SAD, (NOT PTSD, OCD) Usually 0.25-2mg BID | Binds GABAa receptor in CNS causing increase in chloride leading to hyperpolarization and membrane stabilization. This drug must be TAPERED off due to relapse |
| cetirizine | Zyrtec | Second Generation antihistamine. Given 5-10mg QD | Histamine 1 receptor inhibitor |
| pantoprazole | Protonix | Proton Pump Inhibior | Inhibits the H/K ATPase in the parietal cells |
| potassium chloride | Klor-Con | Electrolyte supplement | Mimic endegenous potassium - essential for nerve conduction, myocardial and smooth muscle contraction, acid-base balance, renal function, carbohydrate metabolism and gastric acid secretion. |
| trimethoprim/sulfamethoxazole | Bactrium, Septra | Sulfa Antibiotic- Broad spectrum: Gram (+ and - ), Atypical , Fungi, and Plasmodium (malaria) | Structural analog of PABA they binds to dihydropteroate synthase which is the first step in dihydrofolic acid synthesis preventing cell wall synthesis. |
| gabapentin | Neurontin | Anticonvulsant, peripheral neuropathy | Unknown but thought to enhance GABA |
| conjugated estrogens | Premarin | Equine estrogen- Vasomotor symptoms | Mimic endogenous estrogen |
| fluticasone | Flonase-nasal, Flovent-inhalant | Nasal steroid-allergic rhinitis (1 spray per nostril daily-50mcg/spray), Asthma-inhalanet(50-100mcg BID) | Three MOA: 1. Anti-inflammatory activity 2. immunosuppresive property 3. Antiproliferative |
| trazodone | Desryl | SNRI antidepressant, off label sleep aid. Given 50-200mg TID for depression, for sleep aid 75-150mg QHs | Inhibits the reuptake of 5HT, Histamine 1, and alpha adrenergic receptors |
| cyclobenzaprine | Flexeril | Skeletal muscle relaxant, anti-muscaranic Given 5-10mg TID | Reduces somatic tone influencing the alpha and gamma motor neuron |
| amitriptyline | Elavil | TCA, anticholinergic -Depression, peripheral neuropathy. 50-300mg QHs | Increase synaptic concentration of 5HT and NE in the CNS. |
| levofloxacin | Levaquin | Fluroquinolone antibiotic, Gram ( - ) Excellent= enterobacteriacae, haemophilus, moraxella, neisseria , P.aeruginosa Gram ( + ) Does NOT Cover MRSA Atypicals: All excellent | TOPO II- DNA gyrase of Gram( -) organisms cannot coil or uncoil DNA TOPO IV- Gram (+) cannot separate into daughter chromosomes |
| tramadol | Ultram | Non-narcotic, analgesic (Risk of seizure with TCA, SSRI, MAO) 50-100mg Q4-6 hrs NTE 400mg/day | Bind to the mu receptor in the CNS causing inhibition to the ascending pain pathway, also inhibits the reuptake of 5HT and NE |
| amlodipine/benazepril | Lotrel | Combination CCB-dihydropyridine & ACE | amlodipine- CCB inhibits the voltage gate calcium channels producing relaxation of coronary smooth muscle & coronary vasodilation. benzapril- Inhibits angiotension converting enzyme decreasing the conversion of AT-I to AT-II thus decreasing RAS |
| fexofenadine | Allegra | Second generation antihistamine (OK with narrow angle glaucoma) Given 60mg BID or 180mg Qd | Block the Histamine 1 receptor thus inhibit the release of mediator from mast cells, eosinophil chemotaxis, endothelial activation |
| valsartan | Diovan | ARB, anti-hypertensive | Inhibits the binding of Angiotension II to AT-1 receptor preventing release of Aldosterone |
| enalapril | Vasotec | ACE inhibitor, anti-hypertensive | Inhibits angiotension converting enzyme decreasing the conversion of AT-I to AT-II thus decreasing RAS |
| diazepam | Valium | BZD, GAD, SAD (Not OCD, PTSD) sleep aid | Binds the GABAa receptor increasing chloride leading to a hyperpolarized membrane and stabilization of membrane. |
| naproxen | Naprosyn | ||
| fluconazole | Diflucan | ||
| lisinopril/HCTZ | Zestoretic | Combination anti-hypertensive | Lisinopril=Inhibits angiotension converting enzyme decreasing the conversion of AT-I to AT-II thus decreasing RAS. HCTZ=inhibits the Na/Cl symporter on DCT |
| ramipril | Altace | ACE inhibitor, Anti-hypertensive | Inhibits angiotension converting enzyme decreasing the conversion of AT-I to AT-II thus decreasing RAS |
| celecoxib | Celebrex | ||
| sidenafil citrate | Viagra | ||
| doxycycline | Vibramycin | ||
| ezetimibe | Zetia | ||
| rosiglitazone | Avandia | ||
| lovastatin | Mevacor | ||
| valsartan/HCTZ | Diovan HCT | ||
| carisoprodol | Soma | ||
| drospiereonon/ethinyl estradiol | Yasmin 28 | ||
| pioglitazone | Actos | ||
| pravastatin | Pravachol | ||
| risedronate | Actonel | ||
| norelgestomin/ethinyl estradiol | Ortho Evra | ||
| citalopram | Celexa | ||
| verapamil | Calan | ||
| amphetamine mixed salts | Adderall XR | ||
| mometasone | Elocon, Nasonex | ||
| folic acid | Folacin, Pteroylglutamic acid | ||
| quetiapine | Seroquel | ||
| losartan | Cozzar | ||
| fenofibrate | Tricor | ||
| carvedilol | Coreg | ||
| methyphenidate XR | Concerta, Ritalin, | ||
| ezetimibe/simvastatin | Vytorin | ||
| insulin glargine | Lantus | ||
| promethazine | Phenergan | ||
| meloxicam | Mobic | ||
| tamulosin | Flomax | ||
| rosuvastatin | Crestor | ||
| glipizide ER | Glucotrol | ||
| norgestimate/ethyinyl estradiol | Trinessa, Ortho Tri-Cyclen, | ||
| temazepam | Restoril | ||
| omeprazole | Prilosec | ||
| cefdinir | Omnicef | ||
| albuterol nebulzer solution | AccuNeb, Proventil | ||
| risperidone | Risperdal | ||
| rabeprazole | Aciphex | ||
| digoxin | Lanoxin,Digitek | ||
| spironolactone | Aldactone | ||
| valacyclovir | Valtrex | ||
| lantoprost | Xalatan | ||
| metformin ER | Glucophage EF | ||
| losartan/HCTZ | Hyazzar | ||
| quinapril | Accupril | ||
| clindamycin | Cleocin | ||
| metronidazole | Flagyl, Metrogel | ||
| tramcinolone | Aristocort, Nasocort | ||
| topiramate | Topamax | ||
| ipratropium/albuterol | Combivent DuoNeb | ||
| ipratropium | Atrovent | ||
| benzapril | Lotensin | ||
| gemfibrozil | Lopid | ||
| irbesartan | Avapro | ||
| glimepiride | Amaryl | ||
| hydroxyzine | Vistaril | ||
| metoclopramide | Reglan | ||
| fexofenadine/pseudophedrine | Allegra-D | ||
| doxazosin | Cardura | ||
| warfarin | Coumadin | ||
| diclofenac | Voltarin | ||
| raloxifene | Evista | ||
| diltiazem | Cardizem | ||
| tolterodine | Detrol LA | ||
| meclizine | Dramamine | ||
| glyburide/metformin | Glucovance | ||
| atomoxetine | Strattera | ||
| duloxetine | Cymbalta | ||
| nitrofurantoin | Macrobid, Macrodantin | ||
| promethazine/codeine | Phenergan with codeine | ||
| olmesartan | Benicar | ||
| mirtazapine | Remeron | ||
| bisoprolol/HCTZ | Ziac | ||
| desloratadine | Clarinex | ||
| oxycodone | Oxycontin | ||
| minocycline | Minocin | ||
| sumatriptan | Imitrex | ||
| nabumetone | Relafen | ||
| olanzapine | Zyprexia | ||
| lamotrigine | Lamictal | ||
| polyethylene glycol 3350 | Glycolax | ||
| acyclovir | Zovirac | ||
| propranolol | Inderal | ||
| dozepezil | Aricept | ||
| butalbital/APAP/caffeine | Fioricet | ||
| niacin | B3, Niaspan | ||
| divalproex | Depakote | ||
| buspirone | Buspar | ||
| methotrexate | Rheumatrex | ||
| budesonide | Rhinocort Aqua | ||
| olmesartan/ HCTZ | Benicar HCT | ||
| terazosin | Hytrin | ||
| metaxalone | Skelaxin | ||
| clotrimazole/betamethasone | Lotrisone | ||
| tadaladil | Cialis | ||
| irbesartan/HCTZ | Avalide | ||
| benzonate | Tessalon | ||
| olopatadine | Patanol | ||
| levonorgestrel/ ethinyl estradiol | Aviane | ||
| famotidine | Pepcid | ||
| nifedipine | Aldalat | ||
| nortriptyline | Pamelor | ||
| hydrocodone/ chlorpheniramine | Tussionex | ||
| nitroglycerin | Nitrostat,Nitroquick | ||
| phenytoin | Dilatin | ||
| fosphenytoin | Cerebyx | ||
| etodolac | Lotine | ||
| atenolol/chlorthalidone | Tenoretic | ||
| phentermine | Adipex-P | ||
| tramadol/APAP | Ultracet | ||
| tizanidine | Zanaflex | ||
| mesalamine | Ascol, Casana, Rowesa | ||
| meprobamate | Miltown | ||
| Atenolol | Tenormin | ||
| Betaxolol | Kerlone | ||
| Bisoprolol | Zebeta | ||
| Metoprolol tarate | Lopressor | ||
| Metoprolol succinate | Toprol XL | ||
| Nadolol | Corgard | ||
| Propranolol | Inderal | ||
| Propranolol long acting | Inderal LA, InnoPran LA | ||
| Timolol | Blocardren | ||
| Acebutolol | Sectral | ||
| Carteolol | Cartrol | ||
| Penbutolol | Levaol | ||
| Pindolol | Visken | ||
| Carvedilol | Coreg | ||
| Labetalol | Normodyne,Trandate | ||
| amoldipine | Norvasc | ||
| felodipine | Plendil | ||
| isradipine IR | DynaCirc | ||
| isradipine CR | DynaCir CR | ||
| nicardipine IR | Cardene | ||
| nicardipine SR | Cardene SR | ||
| nifedipine SR | Procardia Xl, Adalat CC | ||
| nisoldipine ER | Sular | ||
| diltiazem IR | Cardizem | ||
| diltiazem SR | Cardizem SR,Dilacor XR,Cardizem LA,Cardizem CR | ||
| verapamil IR | Calan | ||
| verapamil SR | Calan SR | ||
| verapamil SR | Verelan | ||
| verapamil controlled onset ER | Covera HS | ||
| verapamil chronotherapeutic | Verelan HS | ||
| benzazepril | Lotensin | ||
| captopril | Capoten | ||
| enalapril | Vasotec | ||
| fosinopril | Monopril | ||
| lisinopril | Prinvil,Zestril | ||
| moexipril | Univasc | ||
| perindopril | Aceton | ||
| quinapril | Accupril | ||
| ramipril | Altace | ||
| trandolapril | Mavik | ||
| candesartan | Atacand | ||
| eprosartan | Teveten | ||
| irbesartan | Avapro | ||
| losartan | Cozzar | ||
| olmesartan | Benicar | ||
| temisartan | Micardis | ||
| valsartan | Diovan | ||
| Chlorthalidone | Hygroton | ||
| Indapamide | Lozol | ||
| Metolazone | Zaroxolyn | ||
| bumetanide | Bumux | ||
| ethacrinic acid | Edecrin | ||
| furosemide | Lasix | ||
| torsemide | Demadex | ||
| Amiloride | Midamor | ||
| triamterene | Dyrenium | ||
| triamterene/HCTZ | Maxide Dyazide | ||
| spironolactone/HCTZ | Aldactazide | ||
| Amiloride/HCTZ | Moduretic | ||
| alprazolam (cs-iv) | Xanax | ||
| clonazepam (cs-iv) | Klonapin | ||
| clorazepate (cs-iv) | Tranxene | ||
| diazepam (cs-iv) | Valium | ||
| flurazepam (cs-iv) | Dalmane | ||
| estazolam (cs-iv) | ProSom | ||
| lorazepam (cs-iv) | Ativan | ||
| oxazepam (cs-iv) | Serax | ||
| temazepam (cs-iv) | Restoril | ||
| triazolam (cs-iv) | Halcion | ||
| buspirone | Buspar | ||
| Chlorodiazepoxide (CS-IV) | Librium | ||
| zaleplon (cs-iv) | Sonata | ||
| zolpidem and CR (cs-iv) | Ambien | ||
| eszopiclone (cs-iv) | Lunesta | ||
| ramelteon | Rozerem | ||
| chloral hydrate (cs-iv) | Somonote | ||
| Amobarbital (cs-II) | Amytal | ||
| butabarbital (cs-II) | Butisol | ||
| secobarbital (cs-II) | Seconal | ||
| cephalexin (po) | Keflex | ||
| cephradine (po) | Velosef | ||
| cefadroxil (po) | Duracef | ||
| cephalothin (iv) | Keflin | ||
| cefazolin (iv) | Ancef | ||
| cefaclor (po) | Ceclor | ||
| loracarbef (po) | Lorabid | ||
| cefprozil (po) | Cefzil | ||
| cefuroxime axetil (po) | Ceftin | ||
| cefuroxime (iv) | Zinacef | ||
| cefoxitin (iv) | Mefoxin | ||
| cefotetan (iv) | Cefotan | ||
| cefpodoxime (po) | Vantin | ||
| cefdinir (po) | Omnicef | ||
| cefditoren (po) | Spectrcef | ||
| cefotaxime (po) | Claforan | ||
| ceftriaxone (iv) | Rocephin | ||
| ceftazidime (iv) | Fortaz | ||
| cefepime (iv) | Maxipime | ||
| Penicillin G (benzylpenicillin) (iv) | Bicillin LA | ||
| Penicillin V (po) | Veetids | ||
| coxacilin (po) | Cloxapen | ||
| dicloxacillin (po) | Dynapen | ||
| nafcillin (iv) | Novaplus Nafcillin | ||
| oxacilin (iv) | Bactocill | ||
| Ampicillin (po and iv) | Principen | ||
| Ampicillin/subactam (iv) | Unasyn | ||
| Amoxicillin | Amoxil, Trimox, Moxilin | ||
| Amoxicillin/clavulanic acid (po) | Augmentin | ||
| ciprofloxacin (po or iv) | Cipro | ||
| levofloxacin (po or iv) | Levaquin | ||
| gemfloxacin (po) | Factive | ||
| moxifloxacin (po or iv) | Avelox | ||
| tobramycin (iv) | Nebcin | ||
| neomycin (po) | Neo-Fradin | ||
| gentamicin (iv) | Garamycin | ||
| amikacin (iv) | Amikin | ||
| vancomycin (iv and po) | Vancocin (PO) | ||
| sulfisoxazole | Gantrisin | ||
| sulfamethoxazole/TMP | Bactrim, Septra | ||
| Sulfadoxine/pyrimethamine | Fansidar | ||
| sulfasalazine | Azulfidine | ||
| sulfacetamide silver | Silvasene | ||
| sulfacetamide | Sulfamylon | ||
| erythromycin | Erythacin, Ery-PED | ||
| clarithromycin | Biaxin | ||
| azithromycin | Z-PAC,TRI-PAK | ||
| telithromycin | Ketek | ||
| clindamycin | Cleocin | ||
| metronidizone | Flagyl | ||
| oxytetracycline (IM) | Terramycin IM | ||
| demeclocycline (po) | Declomycin | ||
| doxycycline | Vibramycin, Monodox, Doryx, Peristat, Doxy-100 (iv) | ||
| minocycline(po and iv) | Minocycin Dynacin | ||
| tigecycline (iv) | Tygacil | ||
| rifampin | Rifadin | ||
| nitrofurantion | Macrobid, Macroantin | ||
| chloramphenicol | Chloromycetin | ||
| quinupristin/dalfopristin ( iv ) | Synercid | ||
| linezolid ( iv and po) | Zyvox | ||
| daptomycin | Cubicin | ||
| aspirin | Ascripitin,Bufferin, Ecotrin | ||
| choline salicylate | Arthropan | ||
| choline mg trisalicylate | Trilisate | ||
| salsalate | Disalcid | ||
| diflunisal | Dolobid | ||
| diclofenac | Voltaren | ||
| diclofenac & misoprostal | Arthrotec | ||
| etodolac | Lodine | ||
| indomethacin | Indocin | ||
| sulindac | Clinoril | ||
| tolmetin | Tolectin | ||
| ketorlac (iv) | Toradol | ||
| fenoprofen | Nalfon | ||
| flurbiprofen | Ansaid | ||
| ibuprofen | Motrin, Nuprin, Advil | ||
| ketoprofen | Orudis | ||
| naproxen | Naprosyn, Aleve, Anaprox | ||
| oxaprozin | Daypro | ||
| meclofenamate | Meclomen | ||
| mefenamic acid | Ponstel | ||
| piroxicam | Feldene | ||
| meloxicam | Mobic | ||
| nabumetone | Relafen | ||
| celecoxib | Celebrex | ||
| cimetidine | Tagament | ||
| famotidine | Pepcid | ||
| nizatidine | Axid | ||
| ranitidine | Zantac | ||
| misoprostol | Cytotec | ||
| esomeprazole | Nexum | ||
| lansoprazole | Prevacid | ||
| omeprazole | Prilosec | ||
| pantoprazole | Protonix | ||
| rabeprazole | Aciphex | ||
| esomeprazole | Nexum | ||
| lansoprazole | Prevacid | ||
| omeprazole | Prilosec | ||
| pantoprazole | Protonix | ||
| rabeprazole | Aciphex | ||
| abacavir | Ziagen | ||
| didanosine | Videx | ||
| emtricitabine | Emtriva | ||
| lamivudine | Epivir | ||
| stavudine | Zerit | ||
| tenofovir | Viread | ||
| zalcitabine | Hivid | ||
| zidovudine | Retrovir-AZT | ||
| delaviripine (can boost protease inhibitors) | Rescriptor | ||
| efavirenz | Sustiva | ||
| nevirapine | Viramune | ||
| fos-amprinavir | Lexiva | ||
| atazanavir | Reyataz | ||
| darunavir/ritonavir | Prezista | ||
| indinavir | Crixivan | ||
| lopinavir/ritonavir | Kaletra | ||
| nelfinavir | Viracept | ||
| ritonavir | Norvir | ||
| saquanavir/ritonavir | Invirase, Fortovase | ||
| tipranavir/ritonavir | Aptivus | ||
| enfuvirtide-SUB -Q | Fuzeon | ||
| maraviroc | Selzentry | ||
| raltegravir | Isentress | ||
| abacavir, lamivudine, zidovudine | Trizivir | ||
| emtricitabine, tenofovir | Truvada | ||
| lamivudine, zidovudine | Combivir | ||
| abacavir, lamivudine | Epzicom | ||
| lopinavir, ritonavir | Kaletra | ||
| efavirenz, tenofovir, emtricitabine | Atripla | ||
| tolbutamide | Orinase | ||
| tolazamide | Tolinase | ||
| chlorpropamide | Diabinese | ||
| glimepiride | Amaryl | ||
| Glipizide | Glucotrol | ||
| Glipizide XL | Glucotrol XL | ||
| Glyburide | Micronase,Diabeta | ||
| repaglinide | Prandin | ||
| nataglinide | Starlix | ||
| metformin | Glucophage | ||
| rosiglitazone | Avandia | ||
| pioglitazone | Actos | ||
| acarbose | Precose | ||
| migitol | Glycet | ||
| pramlintide Sub-Q | Symlin | ||
| exenatide- Sub Q | Byetta | ||
| sitagliptin (po) | Januvia | ||
| atorvastatin | Lipitor | ||
| fluvastatin | Lescol | ||
| lovastatin | Mevacor | ||
| pravastatin | Pravacol | ||
| rosuvastatin | Crestor | ||
| simvastatin | Zocor | ||
| fenofibrate | Tricor | ||
| colestipol | Colestid | ||
| niacin ER | Niaspan | ||
| niacin SR | Nitrobid, Niacin | ||
| ezetimibe | Zetia | ||
| ezetimibe + simvastatin | Vytorin | ||
| niacin + lovastatin | Advicor | ||
| solifenacin | Vesicare 5-10mg QD | Anti-cholinergic-muscaranic M3 selective- For overactive bladder | Antagonist to the M3 receptor decreasing bladder spasms and promoting filling of the bladder. |
| darifenacin | Enablex 7.5-15mg QD | Anticholinergic-muscaranic- M3 selective for overactive bladder | Antagonist to the M3 receptor relaxed bladder smooth muscle decreasing spasms and promoting bladder filling. |
| selegline | Emsam patch | MAO (6-12mg Q24hr) antidepressant | Inhibits monoamine oxidase |
| trihexyphenidyl HCl | Artane | Antispasmotic agent, Antichoninergic | relaxing effect on smooth musculature; exerted both directly upon the muscle tissue itself and indirectly through an inhibitory effect upon the parasympathetic nervous system. |
| imipramine | Tofranil | TCA antidepressant or childhood enuresis | Inhibit the reuptake of NE and 5HT 25mg TID |
| methimazole | Tapazole | Hyperthyroid agent | inhibits the synthesis of thyroid hormones and thus is effective in the treatment of hyperthyroidism. |
| Bismuth Subsalicylate/metronidazole/tetracycline hydrochloride) | Helidac | Antibiotic with GI agent | These agents are effective on H. pylori |
| cotisone acetate | Cortone | Steroid glucocorticoid | Antiinflammatory and replacement steroid |
| sulindac | Clinoril | NSAID | Non-selective COX1 and COX2 inhibitors |
| docusate | Colase, Ex-lax stool softner | Emollent Laxative | Emollients are anionic surfactants. |
| pyrazinamide | Terbrazid | Antitubercular agent (TB) | Converted to pyrazinoic acid by strains of mycobacterium which lowers pH |
| pyridoxine | Aminoxin (B6) | Vitamin or Antidote | Given with isonaizid to decrease peripheral neuropathy and hepatotoxicity |
| atovaquone | Mepron | Antiprotozal | may inhibit electron transport chain in mitochondria, effective on primary prophylaxis of PCP (or Bactrium DS) |
| allopurinol | Zyloprim | Antigout | Xanthase oxidase inhibitor reduces amount of uric acid produced |
| eplerenone | Inspra | Selective Aldosterone inhibitor | Binds the mineralcorticoid receptors in kidney, brain, heart, blood vessels- Less gynomastica and more selective than spironolactone |
| colesevelam | Welchol | Bile acid sequestrant | Prevents the absorption of cholesterol in the brush border. Does not cause chelation. |
| quinidine | Cardioquin | Class 1A antiarrhythmic | Inhibits Na channel increasing ERP |
| procainamide | Pronestyl | Class 1A antiarrhythmic | Inhibits Na channels increasing ERP |
| disopyramide | Norpace | Class 1A antiarrhythmic | Inhibits the Na channels increasing the ERP |
| lidocaine | Xylocaine | Class 1B antiarrhythmic | Inhibits the Na channels with no effect on ERP |
| mexiletine | Mexitil | Class 1B antiarrhythmic | Inhibits the Na channels with no effect on ERP |
| propafenone | Rythmol | Class 1C antiarrhythmic | Inhibits the Na channels and increases the ERP |
| flecainide | Tambocor | Class 1C antiarrhythmic | Inhibits the Na channel and increases the ERP |
| metoprolol | Toprol XL | Class II antiarrhythmic | Inhibits CCA and decrease SA and AV conduction |
| propranolol | Inderal | Class II antiarrhythmic | Inhibits CCA's to decrease SA and AV conduction |
| esmolol | Brevibloc | Class II antiarrhythmic | Inhibits CCA's to decrease SA and AV conduction |
| amiodarone | Cordarone | Class III, antiarrhythmic | Inhibits the potassium channel to increase ERP |
| dofetilide | Tikosyn | Class III, antiarrhythmic | Inhibits the potassium channel to increase the ERP |
| Ibutilide | Corvert | Class III, antiarrhythmic | Inhibits the potassium channel to increase the ERP |
| sotalol | Betapace | Class III, antiarrhythmic | Inhibits the potassium channel to increase the ERP |
| verapamil | Calan, Covera | Class IV, antiarrhythmic | Inhibits the Ca channels to increase EPR and decrease AV conduction |
| diltiazem | Cardizem | Class IV, antiarrhythmic | Inhibit the L-Ca channels to increase ERP and decreaser AV conduction |
| adenosine | Adenocard | Miscellaneous antiarrhythmic | Inhibits SA and AV conduction and promotes potassium channel activation to shorten AP |
| digoxin | Lanoxin | Miscellaneous antiarrhythmic | Stimulates vagal (parasympathetic) activates potassium channel to shorten AP. |
| doxepin | Sinequan | TCA | Inibits the reuptake of NE and 5HT |
| pentamidine | Nebupent | Sulfa antibiotic | Used for PCP or Leishmaniasis, may involve reactions with ubiquitin |
| desipramine | Norpramin | TCA | inhibits the reuptake of NE and 5HT |
Created by:
liza001
Popular Pharmacology sets