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wcc immunity
various immunity terms / desc
| Term | description |
|---|---|
| T-lymphocytes | cell mediate immunity; killers, helpers, suppressors |
| B-lymphocytes | antibody production/Ig production; plasma and memory cells |
| Natural Killer | do not require an antigen to become active |
| Leukocytes | white cells |
| neutrophils | clear, granulocytes |
| eosinophils | red, granulocytes |
| basophiles | blue/purple, granulocytes |
| monocytes | agranulocytes, contain vacuoles which don't stain |
| lympocytes | agranulocytes, huge nucleus |
| lymphocytes | NK, T-Killer, B, |
| macrophage | monocytes to macrophage |
| phargocytosis | macrophages, momocytes, and neutrophils |
| interferon | prod when cell is infected |
| complement | enzymes that work together to lyse membrane of foreign cells |
| specific immunity | aimed at specific antigens, b cells |
| cell mediate immunity | T cells |
| cytotoxic T cell | attach to antigen and kills |
| helper t cell | lymphokines, attract other immune cells |
| suppressor t cells | negative feedback, inhibit b cell (plasma) |
| Humoral Immunity | B cell production, specific antigen |
| Plasma cell (b) | produces Ab |
| Memory (b) | clones the original b cell, quick immune response |
| IgM | 1st responder |
| IgG | chronic exposure, 2nd responder, good immune response |
| IgA | mucosal linings (aakkk) |
| IgE | attached to mast cells |
| Natural passive imm | colostrum, limited |
| natural active imm | development of antibodies during disease process |
| artificial passive imm | antiserum containing antibodies from another host |
| artificial active imm | vaccination |
| attenuated | strain is mixed with an adjuvant |
| adjuvant | aggravates the skin to increase response |
| feline fibrosarcoma | tumor at injection site |
| MLV | fever, lethargry from Modified live |
| anaphylactic | type 1 |
| granulomas | type 4 |
| Type 1 | immediate, IgE |
| Type 2 | cytotoxic; AIHA (autoimmune hemolytic anemia) |
| type 3 | immune complex; rheumatoid arthritis, arthus reaction, glomerulonephritis |
| type 4 | delayed; granulomas, TB testing, AIHA, Autoimmune skin disorders, myasthenia gravis, lupus keratitis sicca |
| AIHA | auto immune hemolytic anemia, type 2, coombs test; Tx predinisone etc. |
| Myasthenia gravis | canines, connections between nerves and muscles leading to muscle wasting |
| Glomerulonephritis | Type 3, vaccine assoc. |
| Lupus | type 2 and 3, inflammation of variety of tissues |
| Autoimmune thyroiditis | type 2 and 4; destruction of thyroid |
| keratoconjunctivitis sicca AKA Keratitis sicca | type 4; immune attack of lacrimal gland (eye) |
| Elisa test | specific antibody test |
| IFA (indirect flourescent antibody) | Fluorescence of the antibody/antigen when ex under microscope |
| CELISA | same as ELISA/gives semi-quantitative results |
| Latex Agglutination | latex particles are coated with antibody and suspended in water, |
| titer | measure of the quantity of a specific antibodies (IgG) |
| Wester Blot | (blank) |
| Polymerase Chain REaction (PCR) | (blank) |
| Serologic Tests | (blank) |
Created by:
wccvettech
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